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New book explores stem cell therapies for heart disease
Date:5/17/2011

n. "From heart failure, to atrioventricular nodal dysfunction (heart arrhythmia), the young but promising field of cell therapy is likely to play a significant role in developing a cure."

Gaudette is an expert on the mechanical aspects of cardiac function. His lab is exploring ways to coax bone marrowderived stem cells to regenerate cardiac muscle and improve the heart's ability to pump blood. Cohen, an expert on the electrical signals that regulate heart rhythms, is using bone marrowderived stem cells to develop an implantable biological pacemaker that could treat cardiac arrhythmias. In addition to editing the book, Cohen and Gaudette contributed chapters based on their own expertise.

The book is organized into four sections: boosting the heart's mechanical function, restoring normal heart rhythms, regenerating specific heart tissues like valves and blood vessels, and the emerging techniques being developed to deliver and assess various stem cells therapies for the heart. It includes chapters from three other WPI faculty members: Tanja Dominko, associate professor of biology and biotechnology, and Raymond Page and Marsha Rolle, assistant professors of biomedical engineering, wrote about work in their labs exploring various elements of tissue regeneration.

"We have learned greatly from the preparation of this text," Gaudette and Cohen write. "We thank the authors for their fine contributions and hope that [this book] contributes to the education of newly committed and veteran stem cells researchers alike."


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Contact: Michael Cohen
mcohen@wpi.edu
508-868-4778
Worcester Polytechnic Institute
Source:Eurekalert  

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