Navigation Links
New blood test may help in the fight against lung cancer

A new blood test could increase the success of a popular lung cancer drug called erlotinib by allowing doctors select which patients will react positively to the drug.

Currently, patients with non-small cell lung cancer receive erlotinib after chemotherapy and other drugs have failed. But erlotinib will only shrink the tumour about 10 per cent of the time.

"This is a step in the right direction that will allow us to eventually personalize a patient's treatment," says Queen's University Oncology professor Lesley Seymour, who was the coordinating physician on the study. "At the moment, we give drugs to patients and if they respond, we are happy and continue the treatment. If they don't, we move on to another drug."

In addition to helping doctors select the best drug treatment for patients, tests such as these will reduce exposure to medical side effects like rash and diarrhea caused by erlotinib, and eliminate financial burdens for a drug that may not benefit the patient. Newer drugs such as erlotinib can cost thousands of dollars for a month of treatment.

The current research is a follow-up to an erlotinib clinical trial between 2001 and 2005 at the Queen's University-based National Cancer Institute of Canada Clinical Trials Group (NCIC CTG), which led to the approval of erlotinib in the treatment of non-small cell lung cancer.

In addition, blood and tissue samples collected in the original trials were used by David Carbone of the Vanderbilt-Ingram Cancer Center in Nashville to validate the blood tests. NCIC CTG and Queen's researchers also did the statistical analysis.

Professor Carbone presented his results on April 30 at the European Society for Medical Oncology Conference in Geneva, Switzerland.

Lung cancer is by far the deadliest form of cancer. There are 24,000 new cases of lung cancer diagnosed every year in Canada and 21,000 deaths.


Contact: Michael Onesi
Queen's University

Page: 1

Related medicine news :

1. Despite tests, high blood pressure hard to recognize in children
2. Blood test may identify lung cancer patients likely to respond to erlotinib
3. Watch Your Cholesterol, Your Blood Pressure ... and This Enzyme?
4. Tight Blood Sugar Control May Not Harm Diabetics
5. Study examines global availability of treatment involving transplantation of blood stem cells
6. Low blood oxygen may lead to heart defects in children with sickle cell disease
7. InBoundMarketingPR: Cord Blood America Newest Inbound Marketing Client
8. USPack Courier Brings Tracking Precision to Medical and Blood Shipments
9. MDS, a blood cancer, strikes nearly 5 times more Americans than previously thought
10. Recommends Confidential Blood Testing During Sexually Transmitted Disease (STD) Awareness Month (April)
11. Knowledge is power in Penn State blood pressure study
Post Your Comments:
(Date:12/1/2015)... ... 01, 2015 , ... Trustify is proud to announce the success of the ... an organization dedicated to ending domestic violence. , Trustify and Becky’s Fund have joined ... survivors of domestic violence. Trustify is also proud to announce the launch of the ...
(Date:12/1/2015)... ... December 01, 2015 , ... Henderson, a town of ... Gigabit Internet through a partnership this year with Aeneas Internet and Telephone. , ... attractive destination for entrepreneurs who want to build a business. Whether startups or ...
(Date:12/1/2015)... Angeles, CA (PRWEB) , ... December 01, 2015 , ... ... coalition of obesity groups has filed a discrimination claim against the U.S. Department of ... coverage in their Affordable Care Act (ACA) plans are breaking the clause in the ...
(Date:12/1/2015)... ... December 01, 2015 , ... Speech and physical therapies are ... innovative technologies and under the right circumstances, these practices can be merged. ... dual-approach to his or her therapeutic sessions, as well as gives the physical ...
(Date:12/1/2015)... , ... December 01, 2015 , ... It’s official: Tattoo ... tattoo — a number even greater among Millennials (a whopping one in three aged ... and more people who are dissatisfied with their ink. In fact, RealSelf , ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... --> --> ... by Type of Drug (Monoclonal Antibodies, Interferon-Alpha, Interleukins, Vaccines, (Therapeutic ... Analysis - Global Forecast to 2020", published by MarketsandMarkets, the ... Million by 2020 from USD 40,281.6 Million in 2015, at ... Browse 37 market data T ...
(Date:12/1/2015)... 2015 Assurex Health, Inc. today announced ... healthcare providers an expanded range of options in ... from depression, anxiety, bipolar disorder, posttraumatic stress disorder ... i .   --> ... addition of two new drug classes, 17 FDA-approved ...
(Date:12/1/2015)... , Dec. 1, 2015  Six months of adjunctive metformin ... type 1 diabetes, according to new research from T1D ... it may have a beneficial effect on measures of obesity, ... issue of the Journal of the American Medical Association ... the effect of metformin on overweight and obese adolescents with ...
Breaking Medicine Technology: