Navigation Links
New blood analysis chip could lead to disease diagnosis in minutes
Date:3/18/2011

a traditional lab. They note, for example, that the sediment in red wine that usually takes days to years to settle can occur in mere seconds on the microscale.

The SIMBAS biochip uses trenches patterned underneath microfluidic channels that are about the width of a human hair. When whole blood is dropped onto the chip's inlets, the relatively heavy red and white blood cells settle down into the trenches, separating from the clear blood plasma. The blood moves through the chip in a process called degas-driven flow.

For degas-driven flow, air molecules inside the porous polymeric device are removed by placing the device in a vacuum-sealed package. When the seal is broken, the device is brought to atmospheric conditions, and air molecules are reabsorbed into the device material. This generates a pressure difference, which drives the blood fluid flow in the chip.

In experiments, the researchers were able to capture more than 99 percent of the blood cells in the trenches and selectively separate plasma using this method.

"This prep work of separating the blood components for analysis is done with gravity, so samples are naturally absorbed and propelled into the chip without the need for external power," said Dimov.

The team demonstrated the proof-of-concept of SIMBAS by placing into the chip's inlet a 5-microliter sample of whole blood that contained biotin (vitamin B7) at a concentration of about 1 part per 40 billion.

"That can be roughly thought of as finding a fine grain of sand in a 1700-gallon sand pile," said Dimov.

The biodetectors in the SIMBAS chip provided a readout of the biotin levels in 10 minutes.

"Imagine if you had something as cheap and as easy to use as a pregnancy test, but that could quickly diagnose HIV and TB," said Benjamin Ross, a UC Berkeley graduate student in bioengineering and study co-author. "That would be a real game-changer. It could save millions of lives."
'/>"/>

Contact: Sarah Yang
scyang@berkeley.edu
510-643-7741
University of California - Berkeley
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. High Blood Pressure Linked to Drop in Walking Speed, Study Finds
2. New device holds promise of making blood glucose testing easier for patients with diabetes
3. Simple blood test detects early emphysema in smokers before symptoms appear
4. Scientists identify molecule that can increase blood flow in vascular disease
5. Blood Pressure Drug Delays Kidney Disease in Diabetics
6. Blood Pressure Drug Does Not Help Those With Atrial Fibrillation
7. Redefining normal blood pressure
8. University of South Florida researchers find blood-brain barrier damaged by disease
9. Transplanting umbilical cord and menstrual blood-derived stem cells offer hope for disorders
10. OHSU physician explores method to reduce blood-clot risk in trauma patients
11. University of Nevada, Reno, teams with IMMY to make new life-saving blood test
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New blood analysis chip could lead to disease diagnosis in minutes
(Date:7/23/2014)... (PRWEB) July 23, 2014 Texas Physical ... physical therapists from their Westlake, Westgate, Liberty Hill, Parmer, ... the professional designation of Orthopaedic Certified Specialist (OCS) ... June. Adriana Juarez, PT, DPT, OCS, Tony Lauretta, PT, ... PT, DPT, OCS, Joseph Leech, PT, DPT, OCS, and ...
(Date:7/23/2014)... Ticket Down is reliable source for cheap ... at the Cotton Bowl. The 2014 Guinness International Champions Cup ... and Canada beginning on July 24. The tournament features teams ... A, English Premier League, and Superleague Greece. Among the teams ... Milan, Liverpool, AS Roma, and Real Madrid. The latter two ...
(Date:7/23/2014)... July 23, 2014 In his latest ... and drug treatment facility CEO Per Wickstrom explains why ... tells you that she or he has never failed ... out lying,” commented Per Wickstrom. “Failure is not the ... compliment to success, because it reveals opportunities and shifts ...
(Date:7/23/2014)... WEDNESDAY, July 23, 2014 (HealthDay News) -- Children and teens ... an early death in adulthood, a new study suggests. ... had a 50 percent greater risk of death during the ... of a parent, according to the report. Although the ... child,s later risk of premature death, it wasn,t designed to ...
(Date:7/23/2014)... AidJoy is delighted to announce that it ... on September 5, 2014 from 7:00 to 11:00 p.m. ... expected to attend this semi-formal event. , "We are elated ... six years," says Jess Dennis, Director of Operations and organizer ... this moment in AidJoy’s history before we launch into our ...
Breaking Medicine News(10 mins):Health News:Texas Physical Therapy Specialists Congratulates New Board Certified Specialists 2Health News:Texas Physical Therapy Specialists Congratulates New Board Certified Specialists 3Health News:Real Madrid vs. AS Roma Tickets Cotton Bowl Dallas, TX: Ticket Down Slashes Ticket Prices on all AS Roma vs. Real Madrid International Champions Cup Tickets 2Health News:Real Madrid vs. AS Roma Tickets Cotton Bowl Dallas, TX: Ticket Down Slashes Ticket Prices on all AS Roma vs. Real Madrid International Champions Cup Tickets 3Health News:Per Wickstrom’s Latest Blog Post Explains why Entrepreneurs Should Plan for Failure 2Health News:Parent's Death May Raise Risk of Early Death for Grown Children, Study Suggests 2Health News:AidJoy’s Inaugural Gala to be Held September 5, 2014 2
... antidepressant Lexapro permitted by Food and Drug Administration, U.S.// ... FDA to sell escitalopram, a generic immitator of the oral ... drug are retained by the Forest Labs till March 2012 ... This copyright is illogical as per Teva. ,Lundbeck, ...
... that volunteers distributing condoms in the province would no longer ... rates of teenage pregnancies//. The trust said that only authorized ... protection measure. ,"My concern is that child ... commented Dr Dean Marshall, deputy chairman of the BMA's Scottish ...
... statement has said that drug maker Cipla Ltd. has ... nevirapine// that is to be marketed in a tablet ... similar approval for ondansetron in the injection form. ... following chemotherapy or radiation therapy for cancer. The drug ...
... increased blood pressure. But according to a recent study ... in giving them an uninterrupted sleep at the same ... results were presented at the American Thoracic Society International ... person's physical health, and this study shows once again ...
... presented at the American Thoracic Society International Conference, it was ... in lower lung function. The study of 2,112 adolescents ages ... of vitamin D, the recommended amount for this age group. ... low dietary intake of vitamin D (157 IU or less ...
... it was found that amino acid, l-cysteine can prevent ... of the cancers occur// in the mouth, pharynx and ... drinking. This results in a strong exposure of the ... research group of Professor Mikko Salaspuro, University of Helsinki ...
Cached Medicine News:Health News:Sleep Apnea Patients Benefit from Breathing Mask 2Health News:Decreased Vitamin D Intake among Teens Results in Decreased Lung Function 2Health News:Finnish research: Cysteine Chewing Gum as a cure for cancers of the mouth 2
(Date:7/23/2014)...  MiMedx Group, Inc.  (NASDAQ: MDXG ... patent-protected regenerative biomaterials and bioimplants processed from human ... initial Investigational New Drug ("IND") application with the ... The IND submission, which was filed yesterday, July ... certain indications of its micronized allografts towards targeted ...
(Date:7/23/2014)... 2014  Dompe, a leader in R&D for new therapeutic ... (Recombinant Human Nerve Growth Factor) has been designated as an ... The candidate drug, developed by the research ... the treatment of neurotrophic keratitis, a degenerative corneal disease that ... is currently without a cure. This is the second orphan ...
(Date:7/23/2014)... , July 23, 2014 Research ... the "Prepackaged Medical Kits and Trays - ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... for Prepackaged Medical Kits and Trays in US$ ... Trays, Ophthalmic Custom Trays, Custom Basin Kits, Custom ...
Breaking Medicine Technology:MiMedx Files Its Initial Investigational New Drug Application 2MiMedx Files Its Initial Investigational New Drug Application 3Dompe announces the Food and Drug Administration (FDA) has granted orphan drug designation to its rhNGF-based treatment for neurotrophic keratitis 2Dompe announces the Food and Drug Administration (FDA) has granted orphan drug designation to its rhNGF-based treatment for neurotrophic keratitis 3Dompe announces the Food and Drug Administration (FDA) has granted orphan drug designation to its rhNGF-based treatment for neurotrophic keratitis 4Prepackaged Medical Kits and Trays - Global Strategic Business Report: Updated 2014 Report 2
... Sept. 30, 2011 Haemonetics Corporation (NYSE: ... quarter of its 2012 fiscal year on October 31, ... hold a webcast to discuss and answer questions about ... 31, 2011. Webcast Link: http://phx.corporate-ir.net/phoenix.zhtml?p=irol-eventDetails&c=72118&eventID=4204617 ...
... Sept. 29, 2011 Boston Scientific Corporation (NYSE: ... ( NE ural C ardiac T her A ... a prospective, randomized, international clinical feasibility study designed to assess ... heart failure patients.  The study will evaluate 96 patients with ...
Cached Medicine Technology:Boston Scientific Begins Enrollment in NECTAR-HF Clinical Trial 2Boston Scientific Begins Enrollment in NECTAR-HF Clinical Trial 3Boston Scientific Begins Enrollment in NECTAR-HF Clinical Trial 4
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: