Navigation Links
New approaches to testing cancer drugs needed -- ESMO press commentary
Date:9/30/2013

Lugano, Switzerland, 28th September -- Research institutes, regulators and the pharmaceutical industry are urged to cooperate to develop new approaches to testing cancer drugs, in order to bring the revolution in personalised medicine to patients across Europe, says the European Society for Medical Oncology.

It has become clear in recent years that each patient's cancer has individual characteristics that are potentially amenable to "personalised" treatments that target those characteristics. But there is still a great deal of work to be done to ensure patients benefit from these developments as quickly as possible.

"We are approaching a time when it will be possible to analyse the tumours of many patients to help us select the most appropriate treatment and to personalize treatment," said ESMO spokesperson Marina Garassino of the Division of Medical Oncology at the Italian National Institute of Cancer.

Selecting drugs for individual patients helps avoid useless treatments, minimise toxicity and reduce costs for society. In an ideal situation, oncologists would like to be able to use such methods to ensure every single patient is treated with the best possible drugs, Garassino said.

A major challenge facing researchers is that it is not always feasible to perform the kind of large clinical trials that regulators have demanded in the past to prove the value of new treatments.

"We are used to comparing different treatments using large phase III trials, where thousands of patients are randomized," Garassino explained.

"This is feasible when the disease is frequent but not when we are working with small groups of patients who have particular tumour characteristics. In those cases, we need to work closely with statisticians to develop new methodological approaches."

"Regulatory agencies must take into consideration that these kinds of studies can provide important, reliable information about these new
'/>"/>

Contact: ESMO Press Office
media@esmo.org
European Society for Medical Oncology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Scripps Florida scientists awarded nearly $1.5 million to develop new approaches to treat cancer
2. GWU consensus report outlines new approaches for evaluating benefits and risks of obesity drugs
3. NIH awards $7.8 million for innovative HIV vaccine approaches
4. As painkiller overdoses mount, researchers outline effective approaches to curb epidemic
5. Cutting-edge approaches to ensuring biologic drug quality focus of forum on bioassays
6. Jan 31 W-2 1099 Form Mailing Deadline Approaches: EzW2 Software Helps Small Businesses Get Form Ready in Time
7. Common Sense Approaches May Stem ICU Delirium
8. Daily-use HIV prevention approaches prove ineffective among women in NIH study
9. New approaches in treating complicated childhood polycystic kidney disease
10. As Summer Approaches, Experts Offer Tips on Preventing Skin Cancer
11. Imprelis Lawsuit News: Minnesota Property Owners Report Imprelis Tree Damage as June 28 Deadline to Opt Out of Imprelis Lawsuit Settlement Approaches, Reports Wright & Schulte
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... Mellon University, working with high-throughput data generated by ... have devised a computational method to determine how ... turn malignant and as they respond to potential ... genes interact with each other in laboratory-grown cells ... the online journal PLOS Computational Biology . ...
(Date:7/24/2014)... Denver, CO (PRWEB) July 24, 2014 In ... the United States has officially put an end to criminal ... legislation marks a new era for marijuana reform in Washington ... in America. The new law replaces criminal penalties for possession ... fine. Growing, selling and the possession of more than an ...
(Date:7/24/2014)... from Penn Medicine shows that incisionless transcatheter aortic ... stay by 30 percent and has no impact ... conventional transfemoral TAVR, which requires an incision in ... the current issue of Circulation: Cardiovascular Interventions ... aortic valve without a traditional open-heart surgical approach. ...
(Date:7/24/2014)... Lynn E. Taylor, M.D., director of The ... the July, 2014 Rhode Island Medical Journal ... eliminating hepatitis c virus infection (hep c or ... capacity to address other health challenges, and improve ... the United States, Taylor says, include lack of ...
(Date:7/24/2014)... 2014 On October 24-25th, 2014, hundreds of ... the Embassy Suites LAX North for DiabetesSisters’ power-packed weekend conference. ... the first time it has convened Los Angeles, CA area. ... to open the entire event to both women with diabetes ... its kind worldwide for women with diabetes, the event offers ...
Breaking Medicine News(10 mins):Health News:Gene changes in breast cancer cells pinpointed with new computational method 2Health News:Gene changes in breast cancer cells pinpointed with new computational method 3Health News:Washington D.C. Decriminalizes Marijuana 2Health News:Penn study: Incisionless transcatheter aortic valve replacement surgery cuts hospital length of stay 2Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 2Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 3Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 4Health News:DiabetesSisters Brings Conference for Women with Diabetes Los Angeles for the First Time 2Health News:DiabetesSisters Brings Conference for Women with Diabetes Los Angeles for the First Time 3
... If you want to lose the kilos you,ve put on over ... to appetite play an important role in your likelihood of regaining ... highest levels of leptin and lowest levels of ghrelin are more ... Doctors often have to deal with patients who, after sticking to ...
... that a bacterium inside the worm acts as a ,disguise, ... it in an ineffective way. The bacteria protect the ... are removed with antibiotics, the immune system responds appropriately, releasing ... Antibiotics are successful against the parasite, but the long treatment ...
... HealthDay Reporter , TUESDAY, Jan. 11 (HealthDay News) -- ... and Advil, can raise the risk of heart ... suggests. Swiss researchers analyzed the results of 31 ... medications are called, and concluded that cardiovascular risk needs ...
... HealthDay Reporter , TUESDAY, Jan. 11 (HealthDay ... cancer surgery experience urinary incontinence afterward, but new research ... problems for a significant number of them. After ... pelvic exercises and bladder control techniques -- the researchers ...
... , TUESDAY, Jan. 11 (HealthDay News) -- The steady, ... and there has been an alarming increase in the number ... The abortion rate in 2008 was 19.6 per 1,000 women ... peak of 29.3 per 1,000 women, according to the nonprofit ...
... Launched on December 2, 2010, Healthy People 2020 ... health of all Americans. A key component, Education for ... People 2020 goals. Formulated by the Healthy People Curriculum ... objectives provides a vehicle for promoting the discussion and ...
Cached Medicine News:Health News:'Yo-yo' effect of slimming diets explained 2Health News:Study sheds new light on river blindness parasite 2Health News:Certain Painkillers Appear to Boost Odds for Heart Attack 2Health News:Certain Painkillers Appear to Boost Odds for Heart Attack 3Health News:Therapy May Help Cut Incontinence After Prostate Surgery 2Health News:Therapy May Help Cut Incontinence After Prostate Surgery 3Health News:Decline in U.S. Abortion Rate Stalls, Report Finds 2Health News:10-year roadmap for reaching public health education goals 2Health News:10-year roadmap for reaching public health education goals 3Health News:10-year roadmap for reaching public health education goals 4
(Date:7/24/2014)...  Lazarus Effect, a medical device company focused ... facilitate removal of blood clots, announced today that ... issued a new patent (U.S. Patent Number 8,795,305) ... TM and ReCover TM devices. ... stent-retriever (stentriever) with an integrated, novel, cover-based protection ...
(Date:7/24/2014)... , July 24, 2014 Consolidated Net ... Business Highlights   , India Business grew ... by 9.33% to Rs. 4,886.70 Mn Rest of World ... Europe Formulations Business grew by 34.53% to Rs. 977.26 Mn ... , Glenmark Pharmaceuticals Limited, the research-led global ...
(Date:7/24/2014)... -- In any given hospital in the country at any ... one hospital-acquired infection, according to the Centers of Disease ... prove fatal. And as increased surveillance has shown that ... per year, infection control efforts have drifted to the ... stronger emphasis is being placed upon innovative and comprehensive ...
Breaking Medicine Technology:Lazarus Effect Receives Notice of Allowance for New US Patent Covering Core Protection Technology 2Glenmark's Consolidated Revenue Increases by 20.08% to Rs. 14,869.40 Mn for Q1 FY 14 - 15 2Glenmark's Consolidated Revenue Increases by 20.08% to Rs. 14,869.40 Mn for Q1 FY 14 - 15 3Glenmark's Consolidated Revenue Increases by 20.08% to Rs. 14,869.40 Mn for Q1 FY 14 - 15 4Employees, Equipment and the Environment: Top Infection Prevention Focuses in Hospitals 2Employees, Equipment and the Environment: Top Infection Prevention Focuses in Hospitals 3
...  Medtronic, Inc, one of the world,s largest medical device ... U.S. Department of Justice (DOJ), the Office of the ... Services, and four relators in a qui tam suit ... in the U.S., including pacemakers and implantable cardioverter defibrillators ...
... A three-drug combination treatment for the blood cancer multiple myeloma ... patients, according to a multi-center study led by Andrzej ... the multiple myeloma program at the University of Chicago Medical ... of the phase I-II study on Dec. 12, 2011, ...
Cached Medicine Technology:Settlement Announced in Medtronic Qui Tam Case 2Drug Combination Highly Effective for Newly Diagnosed Myeloma Patients, Study Finds 2Drug Combination Highly Effective for Newly Diagnosed Myeloma Patients, Study Finds 3
Reliable and Affordable. The Schuco 3000 Nebulizer by Allied has been designed to offer a compact style that provides worry-free affordable nebulizer therapy....
... CNBT technology, which relieves the practitioner of the ... HOPE allows you the ability to mix medications ... be easier, with a length of oxygen tubing ... the HOPE nebulizer into an inexpensive alternative to ...
... utilizing Vibrating Mesh Technology to efficiently ... from Asthma, COPD or other respiratory ... size and handy carrying case that ... them. Powerful delivery comparable to table-top ...
... dilution nebulizer allows the clinician to deliver up ... into the side port for precise high flow ... for normal flow patients, delivers 8-12 lpm in ... side port. For your high flow needs, DHD ...
Medicine Products: