Navigation Links
New approaches to protecting transplanted organs make first steps toward patients
Date:12/3/2008

f HLA-G dimer. Now they'll look at more patients to see if the finding holds true and look at IDO levels as well to see how they correlate with transplant success.

They'll also look for novel biomarkers of transplant rejection. An Austrian group already has documented increased IDO activity as a prelude to a rejection episode, said Dr. Mellor, noting that in this scenario IDO could be rallying like firefighters to battle rejection. "It's a potential early marker of a problem that transplant physicians will want to deal with," he said, noting that IDO's role may differ in immediate acute rejections and more chronic rejection episodes.

By the end of three-year grant, MCG researchers in collaboration with Dr. Alan D. Kirk, scientific director of the Emory Transplant Center and GRA Eminent Scholar in Transplantation Immunology, want to move to the next step: to see if IDO can protect kidney transplants in non-human primates. If the promised potential holds up, the following step would involve transplant patients at MCG and Emory.

An MCG research team led by Drs. Mellor and David Munn found a decade ago that IDO was a primary mechanism for localized immune tolerance. Since then, they have explored the potential of increasing IDO expression to combat autoimmune disease such as type 1 diabetes and help transplanted organs survive and, conversely, turning IDO off to help kill tumors and attack infections such as HIV. Drs. Mellor and Munn co-direct a new Immuno Discovery Institute in the MCG School of Medicine which will help strengthen this type of translational science.


'/>"/>

Contact: Toni Baker
tbaker@mcg.edu
706-721-4421
Medical College of Georgia
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Employers “Vote” on Presidential Candidates' Health Care Platforms: Prefer Middle Ground Between the Two Approaches
2. Presidential candidates health plans offer divergent approaches to health system reform
3. Ingenious Med Continues Record Customer Growth and Approaches Key Milestones
4. Studies test new approaches to islet transplantation
5. Retooling Talent Management Approaches to Find, Grow & Retain Tomorrows Leaders
6. New report highlights variations in approaches to thoracic surgery in the United Kingdom and Ireland
7. Routinely used diagnostic approaches: only limited diagnostic sensitivity for bile duct cancer?
8. Mathematical modeling offers new approaches to fight dual-resistant hospital infections
9. Doctors uncertain about approaches to care for heart failure patients, SLU study finds
10. Research Highlights New Approaches to Management of Blood Clotting and Bleeding Disorders
11. Pediatricians Awarded for Innovative Approaches to Combat Childhood Obesity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New approaches to protecting transplanted organs make first steps toward patients
(Date:9/2/2014)... patients recover from cancer surgery may be influenced ... operations themselves. Family conflicts and other non-medical problems ... Mayo Clinic study has found. Addressing such quality-of-life ... speed their recoveries and save health care dollars, ... colon cancer patients, and found that patients with ...
(Date:9/2/2014)... According to a new report ... global authority in medical device market research, the ... to grow to over €2 billion in 2020. ... the number of procedures for the treatment of ... includes TURP devices, laser BPH devices, brachytherapy, urinary ...
(Date:9/2/2014)... On Saturday, September 6, 2014, The Concilio will present its ... Get Up! Get Moving!®. This event promotes Hispanic family physical ... people of all ages and all sizes. The event, which ... at Kiest Park Recreation Center, 3080 S. Hampton Road, in ... 2007, we have partnered with National Alliance for Hispanic Health ...
(Date:9/2/2014)... Shrewsbury, MA (PRWEB) September 02, 2014 ... the launch of a Free-Tuition Guarantee for its ICD-10 ... is to bring the highest level of confidence to ... as a medical coder, but are faced with the ... delay the implementation of ICD-10 until October 1st, 2015. ...
(Date:9/2/2014)... Amy Norton HealthDay Reporter ... who want to lose weight and boost their heart health, ... fat, a new study suggests. In a small clinical ... follow a low-carbohydrate diet lost more weight over a year ... had bigger improvements in their cholesterol and triglyceride levels, the ...
Breaking Medicine News(10 mins):Health News:Family conflicts, other non-physical worries before cancer surgery raise patients' complication risk 2Health News:European Urological Device Market Is Expected to Grow to over €2 billion by 2020: Led by Coloplast, Wellspect HealthCare, Teleflex, C. R. Bard and Olympus 2Health News:European Urological Device Market Is Expected to Grow to over €2 billion by 2020: Led by Coloplast, Wellspect HealthCare, Teleflex, C. R. Bard and Olympus 3Health News:The Concilio Presents Eighth Annual ¡Vive Tu Vida! Get Up! Get Moving!® Event 2Health News:The Concilio Presents Eighth Annual ¡Vive Tu Vida! Get Up! Get Moving!® Event 3Health News:The Concilio Presents Eighth Annual ¡Vive Tu Vida! Get Up! Get Moving!® Event 4Health News:American Healthcare Documentation Professionals Group (AHDPG) Launches Free-Tuition Guarantee for Its ICD-10 Medical Coding Bridge Program 2Health News:American Healthcare Documentation Professionals Group (AHDPG) Launches Free-Tuition Guarantee for Its ICD-10 Medical Coding Bridge Program 3Health News:Low-Carb Beats Low-Fat for Weight Loss, Heart Health: Study 2Health News:Low-Carb Beats Low-Fat for Weight Loss, Heart Health: Study 3
... that the nerve cells of the brain remain the same throughout ... a human body most of the organs go through a continuous ... liver take an approximate of two years to be totally replaced ... that the cells of the brain do not go through this ...
... in the journal Nature Clinical Practice Endocrinology and ... high calorie,// low fat western diet to be ... a Pediatrician at the Children's Hospital of the ... current western food environment has become highly insulinogenic, ...
... tendency of waning as we age, but this can be ... ,The positive influence of exercise on cognitive abilities, as ... substantiated by scientists, who also say that even moderate physical ... dementia in later life. ,While some studies ...
... for the heart as red, says a new study.// ... were good for the heart. ,Grape skins are ... skins are separated for preparing white wine. A group of American ... or equal amounts of grape pulp extract, or grape skin extract ...
... from mouse embryos or adult mice to behave like ... details appear// in an immediate early publication of the ... "induced pluripotent stem cells" (iPS) behaved physically and genetically ... might be used to treat a host of diseases, ...
... of drug users who completed the treatment for drug addiction, has ... people enrolling// for the treatment in this period. Drug users were ... coerced into it by the criminal justice system than if they ... study of the outcome of treatment for drug addiction, published today ...
Cached Medicine News:Health News:Studies Show That Brain Cells Do Not Regenerate But Remain The Same Throughout 2Health News:Only A Few Differentiating Factors Between Adult And Stem Cells 2
(Date:9/2/2014)... and ,S-HERTOGENBOSCH, the Netherlands , Sept. ... has expanded its North American operations through its subsidiary ... warehousing, fulfillment and order to cash services for medical ... utilizing our global ERP platform. Building on ... customers in Europe with customer ...
(Date:9/2/2014)... , Sept. 2, 2014 /PRNewswire-iReach/ -- The ... by universal healthcare coverage and good access to ... population and its associated disease burden, well-defined regulatory ... introduction of a new manufacturing policy will drive ... However, a focus on generic substitution and price ...
(Date:9/2/2014)... Sept. 2, 2014  Based on its recent ... market, Frost & Sullivan recognizes Novian Health, Inc. ... Award for Technology Innovation Leadership. Novian Health has ... malignant tumors with its proprietary technology, Novilase ® ... reliable, accurate, and easy-to-control ultrasound-guided thermo ablation device ...
Breaking Medicine Technology:HealthLink Europe opens North American medical warehouse operation 2Australia Medical Devices Market worth $10.4 billion by 2020 Says a New Report Available at MarketOptimizer.org 2Australia Medical Devices Market worth $10.4 billion by 2020 Says a New Report Available at MarketOptimizer.org 3Australia Medical Devices Market worth $10.4 billion by 2020 Says a New Report Available at MarketOptimizer.org 4Australia Medical Devices Market worth $10.4 billion by 2020 Says a New Report Available at MarketOptimizer.org 5Novian Health Wins Acclaim from Frost & Sullivan for Novilase Interstitial Laser Ablation Therapy for Early-Stage Malignant Breast Tumors 2Novian Health Wins Acclaim from Frost & Sullivan for Novilase Interstitial Laser Ablation Therapy for Early-Stage Malignant Breast Tumors 3Novian Health Wins Acclaim from Frost & Sullivan for Novilase Interstitial Laser Ablation Therapy for Early-Stage Malignant Breast Tumors 4Novian Health Wins Acclaim from Frost & Sullivan for Novilase Interstitial Laser Ablation Therapy for Early-Stage Malignant Breast Tumors 5
Used for access and catheterization procedures. Double flexible tipped design permits alternative use of both ends of wire guide depending upon procedural needs. Supplied sterile in peel-open package...
Used for access and catheterization procedures. Double flexible tipped design permits alternative use of both ends of wire guide depending upon procedural needs. Supplied sterile in peel-open package...
... System is Guidant's first in a new ... is stronger and more radiopaque than stainless ... have similar strength and visibility as a ... are only .0032" thick. Thinner struts make ...
Stent delivery with extra rail support...
Medicine Products: