Navigation Links
New antiviral drug shows promise for dramatic improvement in hepatitis C treatment
Date:8/9/2010

INDIANAPOLIS Adding a direct acting anti-viral drug to the standard treatment regimen for hepatitis C significantly increases the cure rate in the most difficult to treat patients, according to a research report published Monday in the online edition of the journal The Lancet.

The research team, led by Paul Kwo, M.D., of Indiana University School of Medicine, reported that adding the drug nearly doubled the treatment's effectiveness when given for 48 weeks in one treatment arm of the study.

An estimated 3.2 million Americans and 170 million people worldwide are infected with the hepatitis C virus, but many do not know it. In the United States, 70 percent of affected individuals are infected with genotype 1 hepatitis C, the most difficult to treat. Although there may be no symptoms for years, long-term infection can cause cirrhosis and the disease is a leading cause of liver cancer and liver transplantation. Hepatitis C infections occur mainly through transmission of infected blood, such as via injection drug use, and there is no vaccine.

Currently fewer than half of patients with genotype 1 hepatitis C are treated effectively by the standard combination of two drugs, peginterferon alfa-2b plus ribavirin, which is typically given for 48 weeks. The treatment can be difficult for some patients due to anemia and other side effects.

Adding the drug boceprevir increased the cure rate to as high as 75 percent in those who received 48 weeks of the three-drug combination therapy, compared to 38 percent of those in the control group, who received the standard two-drug treatment for 48 weeks, said Dr. Kwo, associate professor of medicine at the IU School of Medicine. The two-year phase 2 trial was conducted at 67 sites with 520 patients in the U.S., Canada and Europe.

In the boceprevir study, known as the SPRINT-1 trial, researchers tested several different options to evaluate the effectiveness of the combination ther
'/>"/>

Contact: Eric Schoch
eschoch@iupui.edu
317-274-7722
Indiana University School of Medicine
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Longer Antiviral Therapy Reduces Lung Transplant Complications
2. Antiviral therapy during compensated cirrhosis most cost-effective approach
3. New Study: Improved Immune System with Gene-Eden, a Natural Antiviral Supplement that Targets Chronic Viruses
4. New anti-viral drug shows promise for dramatic improvement in hepatitis C treatment
5. Surgery better than radiation, hormone treatments for some prostate cancer, study shows
6. Women Can Safely Get Pregnant Right After Miscarriage, Study Shows
7. Study shows splitting bowel preparation dosage is most effective cleansing method before colonoscopy
8. Epilepsy Drugs Dont Raise Suicide Risk, Study Shows
9. Iron-regulating protein is strong predictor of breast cancer prognosis, study shows
10. Brain study shows that thinking about God reduces distress -- but only for believers
11. Survey of coastal residents shows Gulf oil spill has significant impact on families
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New antiviral drug shows promise for dramatic improvement in hepatitis C treatment
(Date:8/29/2014)... 2014 A recent article discusses ... a Tokyo clothing store for men with gynecomastia, or male ... or diminishing their problem. Board-certified plastic surgeon Dr. Chasan is ... While many people only associate male breasts with men who ... among men of all ages, often starting in adolescence. Men ...
(Date:8/29/2014)... Aug. 29, 2014 (HealthDay News) -- Astronauts may ... appears to disrupt human immune systems, a new study ... any long missions to asteroids, the moon and Mars ... flu while in space can be dangerous, NASA researchers ... cells in the blood of International Space Station crew ...
(Date:8/29/2014)... TX (PRWEB) August 29, 2014 Carson ... website to provide hearing health care tips to local ... established blog section will offer weekly articles from the ... of topics including the latest advances in hearing restoration ... asked questions. The audiologists plan to write a new ...
(Date:8/29/2014)... trials based on administering antidepressants for acute and ... trials are needed to determine whether these drugs ... regular basis., Dr. Ian Gilron, a professor and ... of Anesthesiology, and his team of seven researchers ... of antidepressants for pain relief post-surgery would work ...
(Date:8/29/2014)... August 29, 2014 The family of ... a series of dialysis treatments has filed a GranuFlo ... was the result of Fresenius Medical Care’s GranuFlo and ... lawsuit, which was file d in Alameda County Superior ... of the products resulted in metabolic alkalosis, a ...
Breaking Medicine News(10 mins):Health News:New Bra Created for Men with Gynecomastia, But Will It Work? 2Health News:New Bra Created for Men with Gynecomastia, But Will It Work? 3Health News:Spaceflight Might Weaken Astronauts' Immune Systems 2Health News:Fort Worth Hearing Aid Leader, Carson Hearing Care, Creates Expert Blog to Discuss Important Hearing Healthcare Topics 2Health News:Fort Worth Hearing Aid Leader, Carson Hearing Care, Creates Expert Blog to Discuss Important Hearing Healthcare Topics 3Health News:Antidepressants show potential for postoperative pain 2Health News:GranuFlo Lawsuit News: Family Alleges Woman’s Death Following Dialysis Was Caused by GranuFlo and NaturaLyte, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuit News: Family Alleges Woman’s Death Following Dialysis Was Caused by GranuFlo and NaturaLyte, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuit News: Family Alleges Woman’s Death Following Dialysis Was Caused by GranuFlo and NaturaLyte, Bernstein Liebhard LLP Reports 4
... first National Women and Girls HIV/AIDS Awareness Day today. ... of the National Institute of Allergy and Infectious Diseases ... said in a press release, “This day of recognition ... HIV/AIDS on women and girls in the United States ...
... a zone in Torun, in northern Poland on the bank of ... Polish vets confirmed the presence of the H5N1 bird flu virus ... the German border but the vets did not confirm whether the ... put by Tadeusz Wijaszka, director of the national laboratory in Pulawy, ...
... WHO, narrowing of the breathing passage, which results due ... biggest killer by 2020. // ,Called ... specific health problems: chronic-obstructive bronchitis and emphysema of the ... narrow due to swelling of the mucous membrane and ...
... denied by the NHS to victims who are suffering the ... saved their day by pitching in. // ,Bupa, ... almost 100 women, who have been diagnosed in the early ... 30 such cases. ,It is estimated that a ...
... not in favor of the rise in Medicare bulk billing, ... // Federal Health Minister Tony Abbott released some alarming statistics ... 75% nationally. ,According to Dr Kim Bulwinkel, from ... to seeing more patients, in order to make it a ...
... Health (OIE) said that the risk of the H5N1 strain ... reported this to the French parliamentary commission on the disease ... risk category. ,It said that the avian flu ... But the Government's chief vet Gardner Murray has rejected the ...
Cached Medicine News:
(Date:8/29/2014)... -- Research and Markets  has announced the addition of ... report to their offering. The Central Nervous ... largest segments of pharmaceuticals industry. The numbers of CNS disorders ... were unable to meet the market requirements. There has been ... especially over the past two decades. The market for CNS ...
(Date:8/29/2014)... SILVER SPRING, Md. , Aug. 29, 2014 /PRNewswire/ ... today that the U.S. District Court for the District ... in its favor in the company,s case against Sandoz, ... opinion, Judge Peter Sheridan ruled that U.S. ... Sandoz, Inc., and enjoined Sandoz from marketing its generic ...
(Date:8/29/2014)... -- Unilife Corporation ("Unilife" or "Company") (NASDAQ: UNIS ... release its financial results for the fiscal 2014 fourth ... trading ends on Tuesday, September 9, 2014. ... p.m. U.S. EDT on Tuesday, September 9, 2014 (Wednesday, ... Company,s financial results, commercial partnerships, and future outlook.  The ...
Breaking Medicine Technology:US CNS Disorders Drug Pipeline Insight 2014 2District Court Decision Received In Remodulin Patent Case 2Unilife Corporation to Announce Financial Results for Fiscal Year 2014 Fourth Quarter and Year End on Tuesday, September 9, 2014 2
... Design for Unparalleled Comfort Pick one of ... balance. Notice the trigger and ejector positionsright where ... our pipettors are ergonomically designed to help avoid ... pipetting. Productivity In The Palm Of Your ...
... Design for Unparalleled Comfort Pick one of ... balance. Notice the trigger and ejector positionsright where ... our pipettors are ergonomically designed to help avoid ... pipetting. Productivity In The Palm Of Your ...
... Finnpipette BioControl multichannel has the ... single channel model. The same ... multichannel and five single channel ... have a recharge and storage ...
... and best value in high performance electronic ... ultra lightweight design reduce hand fatigue and ... lever tip ejector , Color coding for ... or for greater performance use Hamilton AdvanTip ...
Medicine Products: