Navigation Links
New anti-viral drug shows promise for dramatic improvement in hepatitis C treatment
Date:8/8/2010

INDIANAPOLIS Adding a direct acting anti-viral drug to the standard treatment regimen for hepatitis C significantly increases the cure rate in the most difficult to treat patients, according to a research report published Monday in the online edition of the journal The Lancet.

The research team, led by Paul Kwo, M.D., of Indiana University School of Medicine, reported that adding the drug nearly doubled the treatment's effectiveness when given for 48 weeks in one treatment arm of the study.

An estimated 3.2 million Americans and 170 million people worldwide are infected with the hepatitis C virus, but many do not know it. In the United States, 70 percent of affected individuals are infected with genotype 1 hepatitis C, the most difficult to treat. Although there may be no symptoms for years, long-term infection can cause cirrhosis and the disease is a leading cause of liver cancer and liver transplantation. Hepatitis C infections occur mainly through transmission of infected blood, such as via injection drug use, and there is no vaccine.

Currently fewer than half of patients with genotype 1 hepatitis C are treated effectively by the standard combination of two drugs, peginterferon alfa-2b plus ribavirin, which is typically given for 48 weeks. The treatment can be difficult for some patients due to anemia and other side effects.

Adding the drug boceprevir increased the cure rate to as high as 75 percent in those who received 48 weeks of the three-drug combination therapy, compared to 38 percent of those in the control group, who received the standard two-drug treatment for 48 weeks, said Dr. Kwo, associate professor of medicine at the IU School of Medicine. The two-year phase 2 trial was conducted at 67 sites with 520 patients in the U.S., Canada and Europe.

In the boceprevir study, known as the SPRINT-1 trial, researchers tested several different options to evaluate the effectiveness of the combination ther
'/>"/>

Contact: Eric Schoch
eschoch@iupui.edu
317-274-7722
Indiana University School of Medicine
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Surgery better than radiation, hormone treatments for some prostate cancer, study shows
2. Women Can Safely Get Pregnant Right After Miscarriage, Study Shows
3. Study shows splitting bowel preparation dosage is most effective cleansing method before colonoscopy
4. Epilepsy Drugs Dont Raise Suicide Risk, Study Shows
5. Iron-regulating protein is strong predictor of breast cancer prognosis, study shows
6. Brain study shows that thinking about God reduces distress -- but only for believers
7. Survey of coastal residents shows Gulf oil spill has significant impact on families
8. Vaccine Shows Some Promise Against Advanced Cancers
9. Women attracted to men in red, research shows
10. Most youth hockey injuries caused by accidents, not checking, UB study shows
11. Most Men With Low-Risk Prostate Cancer Treated Aggressively, Study Shows
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New anti-viral drug shows promise for dramatic improvement in hepatitis C treatment
(Date:9/23/2014)... By Kathleen Doheny ... -- For babies born at very low birth weights, breast ... to a potentially dangerous infection known as cytomegalovirus (CMV), a ... very low birth weight infants -- all of whom weighed ... mothers with a history of CMV infection, to see whether ...
(Date:9/23/2014)... medicine is rapidly developing, bringing with its advances ... optimize prevention and treatment interventions. Genetic tests ... virus (HIV) and hepatitis c virus (HPC), and ... used to screen for an individual,s susceptibility to ... for addiction. , While there appear to be ...
(Date:9/23/2014)... (PRWEB) September 23, 2014 What: ... Manhattan’s Upper West Side that embodies the inclusion ... Eden: Christians, Scripture and the Ecological Crisis, a ... B. Rhodes Professor Emerita of Old Testament at ... for ancient wisdom that lends insight into current ...
(Date:9/23/2014)... Men who are already obese as teenagers could grow ... their peers of normal weight. So says Petter Lundborg ... Dan-olof Rooth of Linneas University and Lund University, all ... the United Kingdom and the United States, and the ... , The researchers analyzed large-scale data of 145,193 ...
(Date:9/23/2014)... Mission Viejo, California (PRWEB) September 23, 2014 ... in the Oracle services market. Included are ... Oracle Resource Augmentation. Trevera supports all versions of ... and associated point releases. , Trevera has ... specifically for organizations that need help with their ...
Breaking Medicine News(10 mins):Health News:Breast Milk a Risk for Spreading Common Virus to Preemies, Study Finds 2Health News:Breast Milk a Risk for Spreading Common Virus to Preemies, Study Finds 3Health News:NYU-Mount Sinai Beth Israel study explores drug users' opinions on genetic testing 2Health News:Inhabiting Eden: Christians, Scripture, and the Ecological Crisis – Public Lecture to Discuss Faith-Based Environmentalism 2Health News:Note to young men: Fat doesn't pay 2Health News:Trevera, Inc adds Management Support to Services 2Health News:Trevera, Inc adds Management Support to Services 3
... the latest salvo in the pay-for-performance medicine, one of the ... plan to rate physicians on its network based on the ... means that patients will be allowed to choose the doctor ... patients. Naturally, doctors are not amused by this idea. United ...
... New Zealand President Murray Dear is not happy with the ... The statistics show that only 60% of diabetic patients // ... diabetics, which is a state, funded program. , ,The ... to the people that diabetics is not properly monitored it ...
... mats spread across the walls of a patient's room ... skin diseases, hypertension and rheumatic complaints, a study says.//,A ... said patients kept in medicated rooms were cured in ... ,The study involved 36 patients, of whom 19 ...
... to chill Chilling can result in bring on common cold ... also approves ratifies the conventional wisdom of mothers about cold. ... without a hat or with wet hair. Since the early ... the online edition of ABC News. , ,Ron Eccles, ...
... overcome from the crisis if a possible epidemic strikes ... flu strikes Japan it could cause more than 64,000 ... have a cabinet meeting next week to discuss various ... cabinet ministers to prepare preventive measures and emergency measures ...
... has attacked the health profession for complacency in its preparations ... a “biological inevitability”. //, ,Last week Donaldson called together ... colleges, to emphasize that the disease could kill between 50,000 ... joke. , He is planning to issue a “protect ...
Cached Medicine News:Health News:Now medicated coir to cure ailments 2Health News:Doctors attacked for complacency against pandemic threat 2
(Date:9/23/2014)... Nuclear medicine market is estimated to ... Nuclear are drugs that contain radionuclide-emitting ionization radiation, ... and treat diseases. Increasing incidences of ... and ready availability of radiopharmaceuticals are the major ... awareness and use of SPECT and PET also ...
(Date:9/23/2014)...   LabStyle Innovations Corp . (OTCQB: DRIO), ... announced that it has closed a $4.2 million ... stock and warrants.  No placement agent was used ... expects to secure net proceeds of approximately $4.1 ... intends to use the net proceeds from the ...
(Date:9/23/2014)... YORK , September 23, 2014 /PRNewswire/ ... solution Face2Gene améliorée lors d,une série de ... ), pionnier dans le domaine de l,analyse ... sa solution au stand n° 1035 lors de ... San Diego , en ...
Breaking Medicine Technology:Global Nuclear Medicine Market - Growth, Trends & Forecasts (2014-2019) 2LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 2LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 3LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 4LabStyle Innovations Closes $4.2 Million Non-Brokered Private Placement Financing 5FDNA exposera sa solution Face2Gene intégrée en ligne avec London Medical Databases (LMD) à l'ASHG 2014 2FDNA exposera sa solution Face2Gene intégrée en ligne avec London Medical Databases (LMD) à l'ASHG 2014 3
... Potential of microRNAs as,Novel Cancer Drug Targets, REHOVOT, ... 2007,/PRNewswire-FirstCall/ -- Rosetta Genomics Ltd , a leading ... Cell by scientists from the Weizmann Institute of ... potential for a,specific, single microRNA (miR-34a) to be ...
... endpoint achieved -- , LAINATE, Italy - July ... positive preliminary results from its,phase II/III study with ... a broad spectrum, semi-synthetic,antibiotic that is not absorbed ... Cosmo's MMX(tm) technology, which delivers the active,ingredient into ...
Cached Medicine Technology:Rosetta Genomics and Weizmann Institute Scientists Identify Role of,microRNA in Cancer Suppression 2Rosetta Genomics and Weizmann Institute Scientists Identify Role of,microRNA in Cancer Suppression 3Rosetta Genomics and Weizmann Institute Scientists Identify Role of,microRNA in Cancer Suppression 4Rosetta Genomics and Weizmann Institute Scientists Identify Role of,microRNA in Cancer Suppression 5Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III,Data with Rifamycin MMX in Infectious Diarrhea 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: