Navigation Links
New anti-cancer components of extra-virgin olive oil revealed
Date:12/17/2008

Good quality extra-virgin olive oil contains health-relevant chemicals, 'phytochemicals', that can trigger cancer cell death. New research published in the open access journal BMC Cancer sheds more light on the suspected association between olive oil-rich Mediterranean diets and reductions in breast cancer risk.

Javier Menendez from the Catalan Institute of Oncology and Antonio Segura-Carretero from the University of Granada in Spain led a team of researchers who set out to investigate which parts of olive oil were most active against cancer. Menendez said, "Our findings reveal for the first time that all the major complex phenols present in extra-virgin olive oil drastically suppress overexpression of the cancer gene HER2 in human breast cancer cells".

Extra-virgin olive oil is the oil that results from pressing olives without the use of heat or chemical treatments. It contains phytochemicals that are otherwise lost in the refining process. Menendez and colleagues separated the oil into fractions and tested these against breast cancer cells in lab experiments. All the fractions containing the major extra-virgin phytochemical polyphenols (lignans and secoiridoids) were found to effectively inhibit HER2.

Although these findings provide new insights on the mechanisms by which good quality oil, i.e. polyphenol-rich extra-virgin olive oil, might contribute to a lowering of breast cancer risk in a HER2-dependent manner, extreme caution must be applied when applying the lab results to the human situation. As the authors point out, "The active phytochemicals (i.e. lignans and secoiridoids) exhibited tumoricidal effects against cultured breast cancer cells at concentrations that are unlikely to be achieved in real life by consuming olive oil".

Nevertheless, and according to the authors, "These findings, together with the fact that that humans have safely been ingesting significant amounts of lignans and secoiridoids as long as they have been consuming olives and extra-virgin oil, strongly suggest that these polyphenols might provide an excellent and safe platform for the design of new anti breast-cancer drugs".


'/>"/>

Contact: Graeme Baldwin
graeme.baldwin@biomedcentral.com
44-079-205-86437
BioMed Central
Source:Eurekalert

Related medicine news :

1. Experimental anti-cancer drug made from corn lillies kills brain tumor stem cells
2. Discovery of widespread tumor growth gene holds promise for effective anti-cancer treatment
3. Aida Granted Additional Anti-Cancer Patent
4. A Chinese medicine compound has satisfactory anti-cancer effects on hepatocellular carcinoma
5. Telomerase enzyme structure provides significant new target for anti-cancer therapies
6. Scientific evidence of the significant anti-cancer effect of milk thistle
7. Carbon monoxide counteracts one side-effect of an anti-cancer drug
8. Synthesis of natural molecule could lead to better anti-cancer drugs
9. Anti-cancer drug damages brain vessels
10. Lixte Biotechnology Holdings, Inc. Announces Further Developments Regarding the Anti-Cancer Activity of Its Patent-Pending Proprietary Compounds
11. Abbott, Genentech and WEHI Collaborate to Research and Develop New Anti-Cancer Drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2017)... ... May 28, 2017 , ... ... proud to announce that Sheldon K. Cho, MD, has joined its Winter Haven ... specialty that concentrates on minimally invasive techniques to treat and manage many types ...
(Date:5/27/2017)... ... May 26, 2017 , ... A May 8 article ... doctor for colds or respiratory issues that are not responsive to antibiotics nevertheless obtain ... doctors may be largely responsible for the problem both in Canada and the United ...
(Date:5/27/2017)... ... May 27, 2017 , ... In any business, follow up is ... of your dental team at presenting treatment, there will always be some patients who ... time and money on best practices when it comes to presenting treatment. After ...
(Date:5/27/2017)... ... , ... Most us are familiar with the sound of occasional popping joints ... Initiative shows that certain people who experience consistent joint popping, grating and grinding ... the opportunity to treat patients before the problem becomes pronounced, potentially hedging off more ...
(Date:5/26/2017)... ... May 26, 2017 , ... The American Parkinson ... more than eighty-nine grant submissions all vying for nearly $1,000,000 in funding that ... field.     , The American Parkinson Disease Association (APDA) is focused on advancing scientific ...
Breaking Medicine News(10 mins):
(Date:5/9/2017)... PORTLAND, Ore. , May 9, 2017 /PRNewswire/ ... company that provides technology solutions to improve the ... reported financial results for the first quarter ended ... that our products enable our customers to identify ... them to intervene before events like heart attacks ...
(Date:5/8/2017)... -- Diplomat Pharmacy, Inc. (NYSE: DPLO)., has completed its acquisition ... care service center company based in Chantilly, ... management programs for leading pharmaceutical manufacturers and health care ... will join Envoy Health Management, LLC , as ... firms, and other service companies. Together, WRB and EnvoyHealth ...
(Date:5/6/2017)... is Stroke Awareness Month and Omron Healthcare is reminding ... prevent a stroke: monitor and manage your blood pressure. ... undetected and uncontrolled hypertension is a leading risk factor ... personal heart health technology, recently evolved its mission to ... and is advancing a national public education effort to ...
Breaking Medicine Technology: