Navigation Links
New analysis shows that patients with Type 2 diabetes and mild renal impairment had similar improvement in blood sugar control and experienced less hypoglycemia with JANUVIA (sitagliptin) compared to sulfonylurea
Date:6/22/2013

WHITEHOUSE STATION, N.J., June 22, 2013 Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced results from a post-hoc pooled analysis showing patients with type 2 diabetes and mild renal impairment treated with JANUVIA (sitagliptin) 100 mg once-daily achieved similar blood sugar reductions as those treated with the sulfonylureas glipizide or glimepiride, with significantly fewer events of hypoglycemia (low blood sugar), and with weight loss instead of weight gain. Results were presented at the American Diabetes Association 73rd Scientific Sessions.

"Chronic renal disease is, unfortunately, an increasingly common problem in patients with type 2 diabetesand one which can complicate physicians' management of their patients' blood sugar control," said Peter Stein, vice president of Clinical Research for diabetes and endocrinology, Merck Research Laboratories. "Treatments which can help patients with diabetes and renal insufficiency get to improved glycemic control, without increasing the risk of hypoglycemia, may be very useful."

Patients taking JANUVIA 100 mg once-daily achieved similar blood sugar reductions (-0.62 LS mean A1Ci reduction from a baseline of 7.6%) as patients taking a sulfonylurea (-0.68 LS mean A1C reduction from a baseline of 7.6%).

Of the patients taking JANUVIA (sitagliptin), 6.8 percent experienced one or more episodes of symptomatic hypoglycemia, compared to 26.2 percent of patients taking a sulfonylurea (p<0.001). Patients taking JANUVIA also experienced weight loss (-0.9 kg or approximately 2 lbs.) compared to weight gain (+1.4 kg or approximately 3 lbs.) with a sulfonylurea (p<0.001).

JANUVIA is indicated, as an adjunct to diet and exercise, to improve glycemic control in adults with type 2 diabetes mellitus. JANUVIA should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis. JANUVIA has not been studied in patients wit
'/>"/>

Contact: Pam Eisele
908-423-5042

Kim Hamilton
908-423-6831
908-391-0131

Carol Ferguson
908-423-4465

Merck


Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. New Avalere Analysis: Top Five Medicare Part D Plans with the Lowest Average Premiums Have Preferred Pharmacy Networks
2. Novel Drug Delivery Systems Market (NDDS): Formulations (Oral & Injectable) Analysis in Research Report at RnRMarketResearch.com
3. China Animal Vaccine Market Analysis to 2017 in New Research Report at ReportsnReports.com
4. Fulgent Therapeutics Announces Their Comprehensive Hereditary Cancer Test Including BRCA1 and BRCA2 Analysis
5. PET medical image analysis improved in order to optimize radiotherapy treatments
6. Laboratory Automation Market: 2017 Equipment & Software, Drug Discovery, Clinical Diagnostics, Genomics & Proteomics Analysis in New Research Reports at RnRMarketResearch
7. BenefitMall Launches New Health Care Reform Compliance Analysis Tool, allCheck
8. Market for U.S. Disposable Syringe & BRICS General & Specialized Syringes Analysis in New Research Report at ReportsnReports.com
9. General Laboratory Equipment Market Analysis and 2017 Forecast in New Research Report at ReportsnReports.com
10. US Drug Watchdog Now Urges All US Citizens with a Metal Hip Implant to get Blood Tests for Cobalt & Chromium and They Now Offer a No Cost Analysis to Check for a Failure
11. Attention Deficit Hyperactivity Disorder Market (ADHD) Analysis & 2018 Forecasts in New Research Report at RnRMarketResearch.com
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... As reported by the Frederick News Post in the ... (8/17), a graduate of the Frederick County Drug Treatment Court has ... with the program. The graduate, Korey Shorb, put together a race ... walk. He plans to donate the proceeds of the event to ... helped him. Shorb, who graduated in 2008, admitted that he would ...
(Date:8/29/2014)... 30, 2014 Market Research Report ... is a professional and in-depth market survey on ... firstly reviews the basic information of Glass microfiber ... report then explores global and China’s top manufacturers ... Production value, and market share etc. , The ...
(Date:8/29/2014)... (PRWEB) August 29, 2014 Healthpointe is ... G. Rodas. Dr. Rodas will be practicing out of ... As a member of Healthpointe’s orthopedic team, ... internal medicine, and board-certified in occupational medicine. , ... title as Medical Director of Raytheon, the world-class defense ...
(Date:8/29/2014)... 2014 Dr. Parsa Mohebi M.D. has developed ... loss achieve great results in hair transplantation. One of ... , an FUE method that harvests facial hair for transplanting ... lets patients whose hair loss classification is 5 and above ... a great alternative for those advanced hair loss patients who ...
(Date:8/29/2014)... (PRWEB) August 29, 2014 Healthpointe ... Chapman University Physical Therapy students via Clinical Rotations. ... University will be shadowing Healthpointe providers and specialists ... them to develop clinical experience and learn professional ... students will gain insight into several patient care ...
Breaking Medicine News(10 mins):Health News:Drug Court Grad Brings More Life to Drug Court Program 2Health News:Drug Court Grad Brings More Life to Drug Court Program 3Health News:Global and Chinese Glass Microfiber Industry Forecasts to 2019 in New Research Report Available at ReportsnReports.com 2Health News:Global and Chinese Glass Microfiber Industry Forecasts to 2019 in New Research Report Available at ReportsnReports.com 3Health News:Global and Chinese Glass Microfiber Industry Forecasts to 2019 in New Research Report Available at ReportsnReports.com 4Health News:Dr. Anthony G. Rodas Joins Healthpointe Team at LAX Office 2Health News:Advanced Hair Loss Patients Can Now Qualify for Hair Transplants Using Facial Donor Hair 2Health News:Healthpointe is Now Offering Clinical Rotations for Chapman University Physical Therapy Students 2
... A large, national multi-center study of thousands of children ... has found that most of those with normal computed ... observation. Of the more than 13,500 children included ... abnormal CT scans or MRIs and none required neurosurgical ...
... than white Americans, even when they have some ... is so, researchers at Columbia University,s Mailman School ... Medicine, surveyed African American adults with recent oral ... findings provide insights into why disparities persist even ...
... DALLAS June 16, 2011 UT Southwestern Medical ... anesthetic drug ketamine produces a fast-acting antidepressant response in ... robust effect at low doses as a fast-acting antidepressant ... "Ketamine produces a very sharp increase that ...
... esophagus may have a lower risk of esophageal cancer ... published online June 16 in the Journal of ... a premalignant condition, and patients who have it are ... signs of esophageal adenocarcinoma, the most common kind of ...
... -- The risk of cancer associated with the condition ... thought, according to a new long-term study. ... undergo routine endoscopies to screen for esophageal adenocarcinoma, a ... a long, thin tube with a camera at the ...
... Louis Children,s Hospital in the summer of 2010 near death ... lungs. Washington University physicians and surgeons at St. Louis ... his life. They collaborated to make several strategic and innovative ... artificial lung in a toddler. Their efforts are reported ...
Cached Medicine News:Health News:Hospitalizing children with normal CT scans after blunt head trauma is not necessary 2Health News:Hospitalizing children with normal CT scans after blunt head trauma is not necessary 3Health News:Why disparities in dental care persist for African-Americans even when they have insurance coverage 2Health News:Why disparities in dental care persist for African-Americans even when they have insurance coverage 3Health News:Barrett's esophagus carries lower risk of malignancy than previously reported 2Health News:Cancer Risk With Barrett's Esophagus May Be Lower Than Thought 2Health News:Washington University surgeons successfully use artificial lung in toddler 2Health News:Washington University surgeons successfully use artificial lung in toddler 3Health News:Washington University surgeons successfully use artificial lung in toddler 4
(Date:8/29/2014)... 29, 2014 According to ... by Extraction type (SFE, Cold Pressed, Organic Solvent, & ... Pharmaceutical, Food Supplements, Fragrance, & Others) - Global Trends ... and segments the Amaranth Seed Oil Market with ... in terms of value. The Amaranth Seed Oil ...
(Date:8/29/2014)... 2014 Research and Markets has ... Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018" ... and Development Trend Forecast of Pharmaceutical Equipment Market in ... China,s pharmaceutical equipment industry in the ... landscape, and business performance of domestic major enterprises, as ...
(Date:8/29/2014)... Aug. 29, 2014   Vittamed Corporation , a neurodiagnostics ... announced today that T. (Teo) Forcht Dagi , MD, ... Board of Directors. " Teo Forcht Dagi ... neurosurgery, medical innovation and venture capital," said Remis Bistras ... to add his clinical, strategic, and entrepreneurial expertise to our ...
Breaking Medicine Technology:Amaranth Seed Oil Market worth $700.6 Million by 2019 2Amaranth Seed Oil Market worth $700.6 Million by 2019 3Amaranth Seed Oil Market worth $700.6 Million by 2019 4Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2Vittamed Adds Prominent Neurosurgeon and Venture Capitalist T. Forcht Dagi to Board of Directors 2
... Organogenesis, Inc. announced that its Apligraf® bilayered living cellular construct ... and other chronic wounds by the Saudi Food and Drug ... a living cell based product used by physicians to heal ... world. "With diabetes being a widespread and growing ...
... 28 Boston Scientific Corporation (NYSE: BSX ... long-term data from the MADIT II clinical trial in ... demonstrates that the life-saving benefits of implantable cardioverter defibrillator ... the first time that long-term data regarding the benefits ...
Cached Medicine Technology:Apligraf® Approved by Saudi Food and Drug Authority for Treatment of Chronic Wounds 2Boston Scientific Welcomes Publication of Analysis Demonstrating Long-Term Survival Benefit for ICD Therapy 2Boston Scientific Welcomes Publication of Analysis Demonstrating Long-Term Survival Benefit for ICD Therapy 3
... important part of managing the disease state ... mean delivering the aerosolized medication to the ... medication waste. Aerosol delivery with the Salter ... including the new NebuTech® HDN®, helps to ...
Wire-wave tongs...
Tongs...
... vitro Nucleic Acid Hybridization Assay ... Chemiluminescence for the Qualitative Detection ... 6,11,16,18,31,33,35,39,42,43,44,45,51,52,56,58,59 and 68 and Analysis ... Groups in Cervical Specimens: HPV ...
Medicine Products: