Navigation Links
New advances in lipid genetics lead to better detection and prevention of major diseases
Date:5/29/2011

increased levels of LDL and triglycerides and decreased levels of HDL, important risk factors for cardiovascular disease", says Dr. Willems.

The researchers used risk scores from these genetic variants to test the hypothesis that their cumulative effects were associated with cardiovascular disease. For this purpose they used genetic data from more than 8000 individuals from the population-based Rotterdam Study and more than 2000 individuals participating in the Dutch family-based Erasmus Rucphen Family study.

They found an association between the LDL risk score and arterial wall thickness, and a strong association of this risk score with carotid plaque. These conditions can cause arterial blockage which leads to stroke. The same risk score was also associated with coronary heart disease.

"Our findings show that an accumulation of common genetic variants with small effects on lipid levels can have a significant effect on clinical and sub-clinical outcomes", says Dr. Aaron Isaacs, who led the project. "In the future, as our knowledge of genetic variation increases, effective pre-clinical genetic screening tools may be able to enhance the prediction and prevention of diseases such as cardiovascular disease."

New genetic variants influencing lipid levels are being identified all the time, the researchers say. "As new variants are discovered, we would like to be able to continue to test them, both singly and combined, for association with cardiovascular disease. The cost of these diseases to individuals, families, society and healthcare systems is immense", says Dr. Willems.

"Cardiovascular disease is the main cause of death in Europe, killing over 4 million people per year. It also represents 23% of the total disease burden (illness and death) across the continent. Managing cholesterol levels is important for prevention. This can be done early in life by effective treatment. We hope that our study, showing that common gen
'/>"/>

Contact: Mary Rice
mary.rice@riceconseil.eu
European Society of Human Genetics
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Led by advances in chemical synthesis, scientists find natural product shows pain-killing properties
2. Society of Interventional Radiology addresses radiation safety, advances best practices
3. Experts to discuss advances in dental sleep medicine treatments for sleep-disordered breathing
4. UT Southwestern research advances fight against kidney cancer
5. Research presented at 2011 GU Cancers Symposium highlights advances in treatment of prostate cancer
6. RIC study suggests researchers are entering a new era of advances in brain research
7. Long-shot discovery may lead to advances in treating anxiety, memory disorders
8. Roundup: 2010 Advances in Heart Disease and Stroke Care
9. Ovarian cancer advances when genes are silenced
10. Blood Cancer Advances May Improve Survival
11. ASHs 52nd Annual Meeting and Exposition showcases the latest advances in the field
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... 2014 Fancyflyingfox.com, the popular online supplier ... has unveiled a new collection of 2014 military ... launched a promotion for these trendy and elegant products. ... launches the special offer to show its appreciation to ... released military ball outfits are provided with deeply discounted ...
(Date:8/20/2014)... PAINWeek, the National Conference on ... Nadelmann, JD, PhD, will deliver the Keynote Address ... and executive director of the Drug Policy Alliance, ... alternatives to the war on drugs. As a ... and internationally, he has played a pivotal role ...
(Date:8/20/2014)... Recently, UWDress.com, the distinguished wedding dress ... birthday party dresses for girls . According to ... and exquisitely handmade by experienced specialists. Now, they are ... , The company’s new items come in various styles: ... length frocks, long elegant backless gowns and so on. ...
(Date:8/20/2014)... An Elle Magazine online report dated August 13, ... Young at Every Age,” offers a set of recommendations to ... These recommendations are offered as a preventative skincare plan. ... and beyond. The first group of recommendations can be universally ... using sunscreen religiously, getting sufficient exercise and sleep, and eating ...
(Date:8/20/2014)... 2014 Today, Zane Benefits, the ... of a new eBook, Affordable Care Act 101. ... owners feel uncertain about how the ACA impacts ... bottom line. , The new eBook outlines key ... navigate their upcoming health insurance decisions. , Read ...
Breaking Medicine News(10 mins):Health News:2014 Military Ball Gowns Offered At Popular Online Store Fancyflyingfox.com 2Health News:PAINWeek Welcomes Ethan Nadelmann, JD, PhD, as Keynote Speaker at 2014 Conference 2Health News:Cheap Birthday Party Dresses for Girls Now Available at UWDress.com 2Health News:Simon Ourian, Kim Kardashian’s Doctor, On Healthy Skin Suggestions for Every Age 2
... study at Duke Univ. has shown that the surgical outcome ... as in non-diabetics. The results were published Aug. 15, 2005, ... In the largest analysis of its kind, Duke University Medical ... surgery for ankle fractures have significantly higher rates of complications ...
... research report presented in the latest BMJ said that ... motivational interviewing by midwives to help pregnant smokers quit ... the smoking habits of the mothers//. ,A third ... they should be offered intensive support to help them ...
... Aug 15. The best single predictor of happiness is ... status only follow health as per a recent study//. ... graduate student Laura Tach from Harvard University measured the ... using analysis from the 1972-2002 General Social Survey. ...
... be on constant rise, though the floodwaters seem to be receding ... Mumbai and Thane district and now the death toll stands ... the Maharashtra Directorate of Health services sources on Monday. ... persons were admitted to various hospitals in Mumbai with complaints of ...
... Bath, UK has found that Cannabinoids derived from Cannabis ... inflammatory bowel diseases like Crohn’s disease and //ulcerative colitis.,"The ... present and functioning in the lining of the gut," ... Bath, explained to Reuters Health. "There is an increased ...
... and the American Academy of Pediatrics (AAP) had recommended ... sports activity in order to prevent //mouth injuries. ... under are injured while playing sports or participating in ... and the AAP annual back-to-school health promotion, when some ...
Cached Medicine News:Health News:Ankle Fracture Surgery – Diabetics fare worse than non-diabetics 2Health News:Ankle Fracture Surgery – Diabetics fare worse than non-diabetics 3Health News:Trained Counselors Counseling Pregnant Smokers To Quit May Not Work 2Health News:Rich are happier then Poor 2Health News:233 Dead in Mumbai and Thane due to Water Borne Diseases 2Health News:Dentists Recommend Kids Use Mouthguard To Protect Them When Doing Sports 2
(Date:8/20/2014)... LAKE CITY , Aug. 20, 2014 ... revolutionary mobile diagnostic platform during a special event at ... Utah , on September 5, 2014. The event, ... LiveStreamed on the ApolloDx website, www.apollodx.com .    ... transform diagnostic testing," said Jared Bauer , Co-Founder ...
(Date:8/20/2014)... LAKE WORTH, Fla. , Aug. 20, 2014  Glades ... Florida , is proud to announce its expansion into ... , which will feature an 8,000-square-foot office space and ... is currently accepting applications for 100 open positions for the ... located at 4560 Lantana Road will serve as the chain,s ...
(Date:8/20/2014)... Aug. 20, 2014   Easy Breathe , the fastest growing ... " Easy Blog " - has received more than 4.5 million ... "We are thrilled that so many people are finding our ... of Easy Breathe. "We,re committed to making sleep apnea more widely ... stay informed about sleep apnea news , troubleshooting advice ...
Breaking Medicine Technology:Glades Drugs Moves to New Corporate Headquarters, 100 Open Positions 2Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 2Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 3Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 4
... Virtual Radiologic (vRad), a technology-enabled national radiology ... Illinois-based radiology practice serving Champaign/Urbana, Effingham, Danville ... a strategic alliance, merging Lakeland with an ... will be called Lakeland Radiology Alliance, and ...
... electromagnetic applications in the healthcare industry, HFSS™ software from ... now provide proof that a biomedical device transmitter design ... that will enable medical device developers to cut development ... (Logo: http://photos.prnewswire.com/prnh/20110127/MM38081LOGO) The FCC ruled in February ...
Cached Medicine Technology:Virtual Radiologic and Lakeland Radiologists Partner to Create Lakeland Radiology Alliance 2Virtual Radiologic and Lakeland Radiologists Partner to Create Lakeland Radiology Alliance 3FCC Approval of Finite Element Method for Biomedical Transmitters Puts ANSYS Software in the Spotlight 2FCC Approval of Finite Element Method for Biomedical Transmitters Puts ANSYS Software in the Spotlight 3FCC Approval of Finite Element Method for Biomedical Transmitters Puts ANSYS Software in the Spotlight 4
... is the most common cause ... 5% of pediatric visits and ... under 5 years. ImmunoSTAT! Rotatvirus ... rule in or rule out ...
The CdTOX A OIA gets the results you need without specimen extraction or instrumentation. Results are available in minutes vs hours or days for EIA or other methods. The combination of performance, ...
... and nerve block procedures, Cadwells disposable ... a precisely machined Trocar (beveled) tip ... 61-cm (24-in) lead wire. Needle is ... use only. A starter kit includes ...
... Back Relief Apron has standard ... the weight from the shoulders ... aid of a 6" wide ... strap keeps apron snug. Belts ...
Medicine Products: