Navigation Links
New advances in lipid genetics lead to better detection and prevention of major diseases
Date:5/29/2011

Amsterdam, The Netherlands: Studying the genetic make-up of different varieties of lipids (fatty molecules) in the blood plasma of an individual can lead to a better and earlier prediction of diseases such as diabetes, atherosclerosis, and heart disease, two researchers will tell the annual conference of the European Society of Human Genetics today (Monday 30 May). In the first study, Dr. Joanne Curran from the Texas Biomedical Research Institute, San Antonio, USA, will tell the conference that lipidomic profiling will become a more reliable early indicator of individuals likely to develop diabetes than the more commonly used predictors such as blood glucose and insulin levels.

Dr. Curran and colleagues from the US and Australia measured 356 different lipid varieties from about 1100 Mexican American members of large extended families who were part of the San Antonio Family Heart Study. The Mexican American population is at high risk of diabetes with about 25% of this population ultimately becoming diabetic. At the start of the research, 861 of the individuals studied did not have diabetes. However, over the 10 year follow-up examined in the study, 110 individuals did develop the disease.

The scientists were able to isolate 128 different varieties of lipids that predicted the progression to diabetes by measuring the the lipidomic profiles of each individual at multiple timepoints during the follow-up period. "The single best predictor we found was a novel component called dihydroceramide (dhCer). This was substantially increased in people with diabetes. It is also heritable, and appears to be an independent risk factor unconnected to blood sugar and insulin levels," says Dr. Curran.

After uncovering the link between dhCer and diabetes, the team searched the genome to find locations that harboured genes that influence dhCer levels. They identified a region on chromosome 3 that appeared to contain a gene with substantial im
'/>"/>

Contact: Mary Rice
mary.rice@riceconseil.eu
European Society of Human Genetics
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Led by advances in chemical synthesis, scientists find natural product shows pain-killing properties
2. Society of Interventional Radiology addresses radiation safety, advances best practices
3. Experts to discuss advances in dental sleep medicine treatments for sleep-disordered breathing
4. UT Southwestern research advances fight against kidney cancer
5. Research presented at 2011 GU Cancers Symposium highlights advances in treatment of prostate cancer
6. RIC study suggests researchers are entering a new era of advances in brain research
7. Long-shot discovery may lead to advances in treating anxiety, memory disorders
8. Roundup: 2010 Advances in Heart Disease and Stroke Care
9. Ovarian cancer advances when genes are silenced
10. Blood Cancer Advances May Improve Survival
11. ASHs 52nd Annual Meeting and Exposition showcases the latest advances in the field
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... findings from Fox Chase Cancer Center paint a relatively ... of breast cancers that have spread to the chest ... that grow into the skin, regardless of size and ... as stage III and called "locally advanced" tumors, ... cancer, often with poor survival. Locally advanced breast cancers ...
(Date:7/9/2014)... used in policing injection drug users in Russia ... , A study, conducted by researchers from ... in collaboration with St. Petersburg Pavlov State University, ... on the health outcomes of a cohort of ... , Those who were arrested by police were ...
(Date:7/9/2014)... N.Y. Although feelings are personal and subjective, ... code that objectively represents emotions across different senses, ... by Cornell University neuroscientist Adam Anderson. , "We ... the orbitofrontal cortex, an area of the brain ... code which captures an individual,s subjective feeling," says ...
(Date:7/9/2014)... There has been a sharp increase in the number ... MyChart, the online, interactive service that allows patients to ... providers, schedule appointments, and renew prescriptions. , Over a ... MyChart each year increased five-fold, while the number ... according to a study by Dr. David Gerber ...
(Date:7/9/2014)... world have been linked to an emerging fungal ... National Institute for Mathematical and Biological Synthesis (NIMBioS) ... , In a series of mathematical models, ... of internal organs in frogs, could cause extinction ... are exposed to the virus every few years, ...
Breaking Medicine News(10 mins):Health News:Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses 2Health News:Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses 3Health News:BU researchers relate arrests with HIV risk environment 2Health News:Study cracks how the brain processes emotions 2Health News:MyChart use skyrocketing among cancer patients, UT Southwestern study finds 2Health News:MyChart use skyrocketing among cancer patients, UT Southwestern study finds 3Health News:Study predicts ranavirus as potential new culprit in amphibian extinctions 2
... ... appear to continue to resist calling for routine brain monitoring to avoid over medication, especially ... preclude ASA advocating greater patient safety. , ... Newport Beach (PRWEB) February 2, 2010 -- The NFL is giving $1 million ...
... Feb. 1 The Long Beach Library Foundation announces the 9th ... Soloist – A Lost Dream, An Unlikely Friendship, and the Redemptive ... for all ages, are scheduled throughout Long Beach from ... OPENING PUBLIC EVENT - An Evening With Steve Lopez – will take ...
... According ... most common negative patterns in a relationship. Angry individuals may be aware of their problem, ... , ... 1, 2010 -- Personal Power Path announces the launch of an anger management app for ...
... 1 President Obama,s budget, transmitted to Congress this ... Initiative.  Based on projections to continue supporting robust U.S. programs ... -- $16.4 billion is required in FY2011.   ... has an opportunity and must work to get the Obama ...
... , , , DES MOINES, ... lawsuit filed by the Connecticut attorney general, it is ... they need to ensure that they are HIPAA compliant. It is ... the small and medium health care providers, ranging from the local ...
... New research from the University of Pennsylvania School ... resolution by helping them quit smoking. Extended use of a ... recommended by manufacturers boosts the number of smokers who ... backslide into the habit while wearing the patch, according to ...
Cached Medicine News:Health News:Brain Damage: NFL ‘Gets It,' American Society of Anesthesiologists Still Appears ‘Asleep' 2Health News:Brain Damage: NFL ‘Gets It,' American Society of Anesthesiologists Still Appears ‘Asleep' 3Health News:Long Beach Reads One Book 'The Soloist' by Steve Lopez 2Health News:President's Budget for Global Health Far Short of What's Needed - Congress Must Fix 2Health News:President's Budget for Global Health Far Short of What's Needed - Congress Must Fix 3Health News:President's Budget for Global Health Far Short of What's Needed - Congress Must Fix 4Health News:Palisade Systems Comments on the HITECH Lawsuit Filed by the Connecticut Attorney General 2Health News:More smokers kick the habit with extended nicotine patch therapy, Penn research shows 2Health News:More smokers kick the habit with extended nicotine patch therapy, Penn research shows 3
(Date:1/15/2014)... , Jan. 15, 2014  Manufacturers, suppliers and distributors ... able to protect their most important business assets, ... ) Because of the highly-competitive ... remains one of the most litigious industry sectors ...
(Date:1/15/2014)... Inc. (Nasdaq: ECTE ) ("Echo"), a medical ... non-invasive, wireless continuous glucose monitoring system, today announced that ... CEO of Echo Therapeutics, will present at "TEN", Noble ... Mr. Doman will make a corporate presentation to ...
(Date:1/15/2014)... 2014 Reportlinker.com announces that a new ... catalogue: PharmaPoint: Atopic ... Analysis to 2022 http://www.reportlinker.com/p01957657/PharmaPoint-Atopic-Dermatitis---India-Drug-Forecast-and-Market-Analysis-to-2022.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Pathology ... India Drug Forecast and Market Analysis to ...
Breaking Medicine Technology:Intellectual Property Insurance for Medical-related Products and Services 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 2PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 3PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 4PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 5
Lyphochek Assayed Chemistry Control requires no special diluent and has good reconstituted stability for enzymes and CO2. It is assayed for most major instruments and methodologies....
Liquichek Therapeutic Drug Monitoring Control (TDM) is a liquid assayed control containing a comprehensive menu of therapeutic drugs, as well as many common ligands. Available in three levels....
Lyphochek Urine Metals Control incorporates two levels of critical trace elements, heavy metals and organic metabolites, and is ideal for environmental and industrial testing....
Liquichek Urine Chemistry Control is a liquid product ideal for monitoring urine chemistry testing procedures. It provides assayed values for urine tests commonly performed on chemistry analyzers and...
Medicine Products: