Navigation Links
New advance in 3-D printing and tissue engineering technology
Date:2/10/2014

Boston, MA Researchers at Brigham and Women's Hospital (BWH) and Carnegie Mellon University have introduced a unique micro-robotic technique to assemble the components of complex materials, the foundation of tissue engineering and 3D printing.

Described in the Jan. 28, 2014, issue of Nature Communications, the research was conducted by Savas Tasoglu, PhD, MS, research fellow in the BWH Division of Renal Medicine, and Utkan Demirci, PhD, MS, associate professor of Medicine in the Division of Biomedical Engineering, part of the BWH Department of Medicine, in collaboration with Eric Diller, PhD, MS, and Metin Sitti, PhD, MS, professor in the Department of Mechanical Engineering, Carnegie Mellon University.

Tissue engineering and 3D printing have become vitally important to the future of medicine for many reasons. The shortage of available organs for transplantation, for example, leaves many patients on lengthy waiting lists for life-saving treatment. Being able to engineer organs using a patient's own cells can not only alleviate this shortage, but also address issues related to rejection of donated organs. Developing therapies and testing drugs using current preclinical models have limitations in reliability and predictability. Tissue engineering provides a more practical means for researchers to study cell behavior, such as cancer cell resistance to therapy, and test new drugs or combinations of drugs to treat many diseases.

The presented approach uses untethered magnetic micro-robotic coding for precise construction of individual cell-encapsulating hydrogels (such as cell blocks). The micro-robot, which is remotely controlled by magnetic fields, can move one hydrogel at a time to build structures. This is critical in tissue engineering, as human tissue architecture is complex, with different types of cells at various levels and locations. When building these structures, the location of the cells is significant in that it will impact how the structure will ultimately function. "Compared with earlier techniques, this technology enables true control over bottom-up tissue engineering," explains Tasoglu.

Tasoglu and Demirci also demonstrated that micro-robotic construction of cell-encapsulating hydrogels can be performed without affecting cell vitality and proliferation. Further benefits may be realized by using numerous micro-robots together in bioprinting, the creation of a design that can be utilized by a bioprinter to generate tissue and other complex materials in the laboratory environment.

"Our work will revolutionize three-dimensional precise assembly of complex and heterogeneous tissue engineering building blocks and serve to improve complexity and understanding of tissue engineering systems," said Metin Sitti, professor of Mechanical Engineering and the Robotics Institute and head of CMU's NanoRobotics Lab.

"We are really just beginning to explore the many possibilities in using this micro-robotic technique to manipulate individual cells or cell-encapsulating building blocks." says Demirci. "This is a very exciting and rapidly evolving field that holds a lot of promise in medicine."


'/>"/>

Contact: Lori J. Schroth
ljschroth@partners.org
617-525-6374
Brigham and Women's Hospital
Source:Eurekalert

Related medicine news :

1. NJ stroke researchers report advances in spatial neglect research at AAN Conference
2. NYU Langone experts present research, clinical advances at neurosurgeons meeting
3. Experimental Gel May Help Those With Advanced Parkinsons
4. Triple negative breast cancer symposium highlights current advances
5. Advanced genetic screening method may speed vaccine development
6. Advanced Prostate Cancer Drug May Help at Earlier Stage
7. Obese More Likely to Be Diagnosed With Advanced Thyroid Cancer
8. Studies See Advances in Detecting, Treating Pancreatic Cancer
9. GW researchers discover biomarker for advanced bile duct fibrosis and bile duct cancer
10. New England Journal of Medicine hails new skin cancer drug as greatest advance yet
11. MDS researchers join forces to advance patient treatments and outcomes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/25/2017)... Marietta, GA (PRWEB) , ... April 25, 2017 ... ... implant and instrument solutions, announces the continuation of its strategic partnership with and ... surgeons in developing nations in the safe and effective management of complex spine ...
(Date:4/24/2017)... WASHINGTON, DC (PRWEB) , ... April 24, 2017 , ... ... was recognized during ATA 2017: Telehealth 2.0 — the American Telemedicine Association’s annual conference, ... the Santana Telehealth Project for using telemedicine to improve the lives of the poor ...
(Date:4/24/2017)... Antonio, TX (PRWEB) , ... April 24, 2017 , ... ... by the glitterati, those unreal icons inhabiting the rarified air of pop and film ... the paparazzi and anyone snapping pictures: the smile. Grins now run the gamut from ...
(Date:4/24/2017)... ... 24, 2017 , ... Veteran Theresa James awoke to the sound of her ... In “Healing Tears,” James depicts every parent’s worst nightmare, when her three children were ... conversations and situations throughout my divorce,” James said. “After the death of my children, ...
(Date:4/24/2017)... ... April 24, 2017 , ... My T Chai, a South African company ... available for purchase on RevNutrition.com, a popular website specializing in sales of nutritional products. ... in ancient India and Siam. It spread across Asia and Africa quickly, and today ...
Breaking Medicine News(10 mins):
(Date:4/18/2017)... , April 18, 2017  Cardinal Health (NYSE: ... 1 fiscal 2017 earnings per share (EPS) guidance ... 2019.  This is in conjunction with this morning,s announcement ... Vein Thrombosis and Nutritional Insufficiency businesses. Cardinal ... continuing operations will be at the bottom of its ...
(Date:4/18/2017)... , April 18, 2017 Research and Markets ... 2017-2021" report to their offering. ... The global arthroscopy devices market to grow at a CAGR ... Global Arthroscopy Devices Market 2017-2021, has been prepared based on an ... the market landscape and its growth prospects over the coming years. ...
(Date:4/18/2017)... SUNNYVALE, Calif. , April 18, 2017 /PRNewswire/ ... results of collaboration started in 2016, in which ... "Artificial Brain SOINN". The companies achieved initial results ... ultrasound solution by Artificial Brain SOINN. The results ... Tokyo Big Sight, April 19-21, at booths 4505 ...
Breaking Medicine Technology: