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New activity found for a potential anti-cancer agent
Date:11/2/2009

iu at Johns Hopkins, found that PatA inhibits the initiation phase of protein synthesis, which gives PatA the potential to fight cancer.

"Tumor cells are more actively producing new proteins than normal cells, so tumor cells are hundreds if not thousands of times more vulnerable to DMDAPatA's inhibition of protein synthesis, which makes DMDAPatA a good candidate as an anti-cancer agent," he explains.

"DMDAPatA is structurally simpler than PatA but exhibits similar activity in inhibiting NMD and protein synthesis," Romo notes. "It has been patented by Texas A&M, evaluated by two pharmaceutical companies, and continues to be evaluated as a potential anti-cancer agent for both human and animal (pet) applications."


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Contact: Daniel Romo
romo@tamu.edu
979-845-9571
Texas A&M University
Source:Eurekalert

Page: 1 2

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