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New UTHealth trial aimed at helping pregnant women stop smoking
Date:5/4/2011

ring pregnancy often say they want to quit for the benefit of their baby, but just can't overcome the need. We currently don't have many pharmacological options to assist them. Therefore, I think this study is extremely important and will impact our patients in a meaningful way," said Sean Blackwell, M.D., co-investigator and associate professor in the Department of Obstetrics, Gynecology and Reproductive Sciences at UTHealth. Blackwell is also the director of UTHealth's Larry C. Gilstrap Center for Perinatal and Women's Health Research.

A 2001 brain activation study published in the Archive of General Psychiatry concluded that bupropion appears to reduce the cravings associated with smoking. "It's an atypical antidepressant and the mechanism is not well known but we believe it works on several systems. We think it's mediated through the dopaminergic and noradrenergic systems," Stotts said. "It might act as an antagonist, blocking the effects of the nicotine, so people might not experience the same pleasant reinforcing properties of nicotine."


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Contact: Deborah Mann Lake
deborah.m.lake@uth.tmc.edu
University of Texas Health Science Center at Houston
Source:Eurekalert  

Page: 1 2

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