Navigation Links
New UT Arlington research could improve pharmaceuticals testing
Date:4/30/2014

A UT Arlington chemistry professor, renowned for his work in the area of chemical separations, is leading an effort to find a more accurate way to measure water content in pharmaceuticals a major quality issue for drug manufacturers.

Daniel W. Armstrong, UT Arlington's Robert A. Welch Chair in Chemistry, says the new technique could be 100 times more sensitive than one of the most popular current methods.

"The analysis for water in many consumer products, including drugs, is one of the most required tests done in the world," said Armstrong. "Current methods have many shortcomings, including poor sensitivity and reproducibility; they cannot be used for all products and they can be time consuming. I believe our new 'ionic liquid' method offers improvements in all these areas."

Armstrong and two graduate students recently wrote about their new research in a paper that will be in the June issue of the Journal of Pharmaceutical and Biomedical Analysis. The publication describes using headspace gas chromatography and an ionic liquid gas chromatography column Armstrong's lab developed to measure moisture content in active pharmaceutical ingredients such as ibuprofen, tetracycline and ephedrine. Water content can affect the stability and shelf life of a drug and, when it is too high, cause microbial growth, according to the paper.

Chromatography is the process of separating a chemical mixture to measure its components. Headspace gas chromatography, or HSGC, involves the measuring of volatile analytes, or chemical components, as they diffuse into a "headspace" at the top of a tube of sample, including solids. The new method combines HSGC with the use of ionic liquids. Ionic liquids consist of a mixture of positively and negatively charged molecules. They have a variety of advantages as solvents.

Currently, two methods are most commonly used to measure moisture content. One is called weight loss on drying, or LOD; the other is called Karl F
'/>"/>

Contact: Traci Peterson
tpeterso@uta.edu
817-521-5494
University of Texas at Arlington
Source:Eurekalert

Page: 1 2

Related medicine news :

1. National Academy of Inventors names 4 UT Arlington professors as fellows
2. George Strait Tickets Dallas Arlington TX at the AT&T Stadium: Cheap Concert Tickets Reports Record Demand for King George's Final Concert in Dallas - Tickets Onsale 12/6
3. George Strait Tickets Dallas TX - AT&T Stadium: Ticket Down Reports Demand is through The Roof for George Strait Tickets in Arlington at AT&T Stadium (Cowboys Stadium)
4. UT Arlington professor will use NSF funds to reveal reactions inner workings
5. Dentist in Arlington, VA, Dr. Michael Rogers Launches New Website
6. Rich Dad Education to Hold 3-Day Financial Workshop in Arlington, VA on Aug. 23-25
7. UT Arlington researcher finds that money motivates employees to lose weight
8. Minimally Invasive SpineCARE® Opens Three New Clinics in Texas Branches out into Burleson, Arlington and Joshua
9. 7th Annual Reglera Reproductive Compliance Conference Slated for September 19-20, in Arlington, Virginia
10. Residence Inn Arlington Pentagon City Hotel Shows Strength With Unveiling of New Fitness Center
11. RE/MAX Suburban Brokers in Arlington Heights Plan June 8 Garage Sale to Benefit Lurie Children’s Hospital
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... ... June 30, 2015 , ... ... amidst bright skies and inspirational words. , The independent, coeducational, special needs ... the Glenholme building to the school’s Center for the Arts. Along the way, ...
(Date:6/30/2015)... ... , ... Intellitec Solutions has announced they will be hosting two webinars to ... changes and new procedures involved with updating the cloud version of Dynamics CRM, attendance ... new user interface and what it will mean for end users, critical items that ...
(Date:6/30/2015)... GA (PRWEB) , ... June 30, 2015 , ... ... achievements of aspiring data scientists and analysts who are currently attending an accredited ... the growth of data has provided new insight into healthcare, the environment, political ...
(Date:6/30/2015)... , ... June 30, 2015 , ... This Fourth of ... with the Peacock Alley story including hard work, tenacity, perseverance, commitment to quality, honesty ... born. , Born of Mary Ella Gabler's simple love of quilts, Peacock Alley ...
(Date:6/30/2015)... Diego, CA (PRWEB) , ... June 30, 2015 , ... ... owner and founder of SunGrubbies.com. “We are particularly interested in getting the word ... can take years to surface. We are extremely pleased with our new ...
Breaking Medicine News(10 mins):Health News:The Glenholme School Graduates Its Class of 2015 2Health News:The Glenholme School Graduates Its Class of 2015 3Health News:The Glenholme School Graduates Its Class of 2015 4Health News:Intellitec Solutions to Host Microsoft CRM 2015 Update Webinar 2Health News:Izenda Offers Embedded BI and Analytics Scholarship 2Health News:Izenda Offers Embedded BI and Analytics Scholarship 3Health News:Luxury Linen Purveyor Peacock Alley Celebrates the Fourth of July 2Health News:SunGrubbies.com, a Leading Online Retailer of Sun Protection Products, Joins Effort to Promote Sun Safety 2Health News:SunGrubbies.com, a Leading Online Retailer of Sun Protection Products, Joins Effort to Promote Sun Safety 3
... is proud to announce the addition of Sandra L. Murman to ... State of Florida and will also join Accelify,s National Board of ... eight years as a member of the Florida House of Representatives ... in the Florida legislature, she personally sponsored and passed 64 bills ...
... MA November 11, 2009 Aileron Therapeutics, a ... of drugs called Stapled Peptides, announced today that its ... Institute and the Broad Institute of Harvard and MIT, ... Harvard University, published research in Nature entitled, ...
... and nonprofit organizations are joining forces to develop new ... claim millions of lives in the developing world each ... and other conditions. That,s the topic of the cover ... Engineering News, ACS, weekly newsmagazine. C&EN Senior Editor ...
... front of teacher or using wireless technologies might help, ... Students with developmental dyslexia may not be able to ... that include banging lockers, scraping chairs and other auditory ... affects reading and spelling skills in 5 to 10 ...
... Report Discusses Emergence ... ... annual State of the Nation’s River report , calling attention to a variety of ... growth and sexual development of vertebrate species, including humans and fish. , , , , ...
... A recent survey of healthcare organizations found that 94 ... privacy and security provision of the Health Information Technology for ... take effect in February. The survey of 77 U.S. ... by Crowe Horwath LLP, one of the largest public accounting ...
Cached Medicine News:Health News:Accelify Announces the Addition of Sandra L. Murman to its National Board of Advisors 2Health News:Accelify Announces the Addition of Sandra L. Murman to its National Board of Advisors 3Health News:Aileron collaborates study in Nature: Stapled peptides inhibit Notch1 transcription factor 2Health News:Aileron collaborates study in Nature: Stapled peptides inhibit Notch1 transcription factor 3Health News:Dyslexia May Make It Tough to Tune Out School Noise 2Health News:The New Pollutants Brewing in Our Water 2Health News:The New Pollutants Brewing in Our Water 3Health News:The New Pollutants Brewing in Our Water 4Health News:Study Shows Most Healthcare Companies Are Not Ready for New Privacy and Security Compliance Regulations 2Health News:Study Shows Most Healthcare Companies Are Not Ready for New Privacy and Security Compliance Regulations 3Health News:Study Shows Most Healthcare Companies Are Not Ready for New Privacy and Security Compliance Regulations 4
(Date:6/29/2015)... , June 29, 2015  PDL BioPharma, Inc. ... entered into a credit agreement with CareView Communications, Inc. ... to $40 million of secured debt financing. CareView is ... on patient care monitoring. Under the credit ... million of debt financing in two tranches of $20 ...
(Date:6/29/2015)... Minn. , June 29, 2015 EnteroMedics ... of devices that use neuroblocking technology to treat obesity, ... it has commenced an underwritten public offering of units. ... stock, Series A warrants to purchase common stock and ... purchase of units in the offering would result in ...
(Date:6/29/2015)... , June 29, 2015  Allergan plc ... intends to release second quarter 2015 financial results ... open of the U.S. financial markets. The Company will ... a.m. Eastern Daylight Time on Thursday, August 6, ... to access the call is U.S./ Canada ...
Breaking Medicine Technology:PDL BioPharma Announces $40 Million Financing Transaction with CareView Communications 2PDL BioPharma Announces $40 Million Financing Transaction with CareView Communications 3PDL BioPharma Announces $40 Million Financing Transaction with CareView Communications 4EnteroMedics Inc. Announces Proposed Public Offering of Common Stock and Warrants 2EnteroMedics Inc. Announces Proposed Public Offering of Common Stock and Warrants 3Allergan to Host Second Quarter 2015 Earnings Conference Call and Webcast 2Allergan to Host Second Quarter 2015 Earnings Conference Call and Webcast 3
... Radiologic (vRad), a technology-enabled national radiology practice, has again ... market segment by independent research and consulting firm KLAS. ... interviews conducted by KLAS and is published in the ... Software & Professional Services report. In ...
... Reportlinker.com announces that a new market research report ... Novo Nordisk A/S: PharmaVitae Profile ... This analysis examines the historical ... prescription pharmaceutical sector. The profile encompasses global company ...
Cached Medicine Technology:Virtual Radiologic Ranked #1 for Teleradiology Services for Third Consecutive Year 2Reportlinker Adds Novo Nordisk A/S: PharmaVitae Profile 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: