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New UCSF Studies Reveal that Age-Related Nerve Decline is Associated with Inflammation and Differs by Gender
Date:4/14/2010

New research investigating neurological decline in a population of “super healthy” elderly subjects found that the decline in neurological function of the peripheral nervous system attributed to aging may be related to metabolic factors, such as blood sugar levels, even if these factors are within the normal range.

(Vocus) April 14, 2010 -- New research investigating neurological decline in a population of “super healthy” elderly subjects found that the decline in neurological function of the peripheral nervous system attributed to aging may be related to metabolic factors, such as blood sugar levels, even if these factors are within the normal range.

In a related UCSF study of peripheral nerve function, the same group found that aging affects the nerves of men more than women later in life.

The findings imply, the researchers say, that age-related declines in peripheral nerve function may not be the consequence of the aging process alone but instead the consequence of aging, gender, plus metabolic factors that may be modifiable. The peripheral nerves are the nerves in the limbs that connect to the central nervous system (brain and spinal cord).

Outcomes from the two studies were presented today by UCSF researchers during the annual American Academy of Neurology scientific meeting in Toronto.

“Reduced sensation from a decline of nerve function may contribute to overall morbidity and reduced quality of life in the elderly,” said Ari Green, MD, co-lead investigator, assistant director of UCSF’s Multiple Sclerosis Center and director of the Neurodiagnostics Center. “The medical community considers this decline a consequence of aging. Our findings suggest that low levels of inflammation and impairment in glucose metabolism may accelerate the decline of nerve function.”
Both studies invo
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