Navigation Links
New UAlberta research shows commonly prescribed medications could have adverse effects
Date:1/17/2013

may be beneficial for hearts impacted by PAH, since endothelin is known to increase the strength of contraction of the heart muscle. In other words, as the right ventricle has to work harder pushing blood through the narrowed blood vessels, endothelin may help it function better, but this may be blocked by ERAs. The research team also showed that, as expected, ERAs decrease the strength of contraction of the diseased right ventricles.

"These new findingsthat ERAs have direct effects on the right chambers of the hearthave important implications for treated patients" said Nagendran. "For example, PAH patients treated with ERAs can develop fluid retention (swelling), which is currently treated with diuretics. As fluid retention can be a result of decreased right ventricle function, the new findings suggest that this could be a previously unrecognized important adverse effect of these drugs."

In other words, while ERAs may have a beneficial effect on the lung blood vessels, they may also have unwanted effects on the heart.

"While this does not mean that PAH patients should stop using these drugs, this new research sheds more light on the overall mechanism of action of these drugs in PAH patients," said Michelakis. "It may also help physicians to better approach the treatment of PAH patients and design clinical studies to validate these new findings in large populations."

PAH tends to mostly affect younger women, although both sexes of all ages can be affected. The survival of PAH patients is similar to that of patients with metastatic breast cancer, but the yearly cost of treatment can be more than double compared to that of metastatic breast cancer, and can exceed $200,000 per patient.


'/>"/>
Contact: Quinn Phillips
quinn.phillips@ualberta.ca
780-399-7505
University of Alberta Faculty of Medicine & Dentistry
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Alternative medicine use high among children with chronic conditions: UAlberta medical research
2. Alternative medicine use high amoung children with chronic conditions: UAlberta medical research
3. UAlberta medical researchers discover new potential chemotherapy
4. UAlberta medical researchers make key discovery in fight against Alzheimers disease
5. UAlberta prostate cancer researcher and team developing homing beacon drugs to target cancer cells
6. UNC researchers use luminescent mice to track cancer and aging in real-time
7. Gothenburg researchers make world top 10
8. New research finds slower growth of preterm infants linked to altered brain development
9. Immunology research sheds new light on cell function, response
10. Autism Researchers Surprised by Impaired Brain Connections
11. Oncologist expands HPV research to anal cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/2/2015)... May 03, 2015 As one of ... the prestigious Safety and Health Achievement and Recognition Program ... to be chosen by the Illinois Department of Labor ... achieved and maintained SHARP certification by the Occupational Safety ... as Essentra has continued to meet or exceed all ...
(Date:5/2/2015)... Vancouver fencing company, QS Fencing, has recently announced ... prospective clients related to their questions on railings and gates. ... their decks and patios. While that seems like an easy ... the person rolls up their sleeve to start working. One ... finding a gate that matches it. , Instead of spending ...
(Date:5/2/2015)... Aliso Viejo, CA (PRWEB) May 02, 2015 ... made exclusively for use in Final Cut Pro X. ... ready for use in Final Cut Pro X . ... a single keyframe with Pixel Film Studios' ProText Kinetic 2. ... drop. Start by staggering two ProText Kinetic presets in ...
(Date:5/2/2015)... (PRWEB) May 02, 2015 We are ... The Delray Recovery Center as one of the Top ... known in the addiction treatment field for their ethics ... to innovate and to continue their educational efforts. The ... workplace environment, never forgetting their purpose – to help ...
(Date:5/2/2015)... On Tuesday April 7th, the patient ... to celebrate improvements in patient care. In 2014 the ... had zero acquired ventilator associated infections, zero central line ... was also recently named a Top Performer by the ... credited the teamwork of staff from all departments involved ...
Breaking Medicine News(10 mins):Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 2Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 3Health News:Professional Staff at QS Fencing Company Now Provides Advice on Railings and Gates 2Health News:Pixel Film Studios Announced the Release of Protext Kinetic 2 for FPCX. 2Health News:The Delray Recovery Center Named 2015 Top Workplace 2Health News:East Liverpool City Hospital Celebrates Patient Care Improvements 2
... Medicare ... ... -- If you’re one of the more than 45 million people relying on Medicare for ... is too expensive, according to Allsup , a nationwide provider of Social Security disability ...
... , , , ... NXTM ), a leading manufacturer of innovative dialysis products, today ... Chief Financial Officer, will be presenting at the UBS Global Life ... Grand Central in New York City. , , ...
... , , BIRMINGHAM, Ala., ... leader in radiology optimization solutions that increase business capacity, productivity ... its Board of Directors has approved changing its name to ... its ability to more accurately represent the precision imaging management ...
... , , FRANKLIN LAKES, N.J., Sept. 1 BD ... that it would present at the following investor healthcare conferences in September: , , ... September 9, 2009, 10:55 ... September 14, 2009, ...
... rank facilities don,t take all measurements into account , TUESDAY, ... onto the U.S. News & World Report list ... in some measurements regarding heart failure, researchers say. , "If ... the areas of heart failure mortality and readmission, you should ...
... , PISCATAWAY, N.J., Sept. 1 Milestone ... advanced injection technologies, today announced that Leslie Bernhard, an independent ... Osser who had previously led the Company as Chairman since ... Chief Executive Officer since February 2009 and was formerly Milestone,s ...
Cached Medicine News:Health News:Allsup Outlines 10 Critical Questions to Answer When Evaluating Medicare Plans 2Health News:Allsup Outlines 10 Critical Questions to Answer When Evaluating Medicare Plans 3Health News:Allsup Outlines 10 Critical Questions to Answer When Evaluating Medicare Plans 4Health News:Allsup Outlines 10 Critical Questions to Answer When Evaluating Medicare Plans 5Health News:NxStage to Present at the UBS Global Life Sciences Conference 2Health News:Optimal Readings Completes Strategic Name Change to Optimal IMX 2Health News:Optimal Readings Completes Strategic Name Change to Optimal IMX 3Health News:Optimal Readings Completes Strategic Name Change to Optimal IMX 4Health News:Optimal Readings Completes Strategic Name Change to Optimal IMX 5Health News:Optimal Readings Completes Strategic Name Change to Optimal IMX 6Health News:Government Best Source for U.S. Hospital Data, Study Finds 2Health News:Milestone Scientific Announces Key Leadership Changes 2Health News:Milestone Scientific Announces Key Leadership Changes 3
(Date:5/1/2015)... Calif. , May 1, 2015 The ... its 2015 health literacy award winners. The IHA Health ... that make an impact on the practice of educating ... health literacy. IHA gives awards in three categories: innovative ... bestowed its Health Literacy Hero award. In ...
(Date:5/1/2015)... Semler Scientific, Inc. (Nasdaq: SMLR ), ... and markets products that assist healthcare providers in monitoring ... for the first quarter ended March 31, 2015. ... reported continued progress with year over year growth of ... 14%," said Doug Murphy-Chutorian , M.D., chief executive ...
(Date:5/1/2015)... -- Shares of Aerie Pharmaceuticals, Inc. (NASDAQ: AERI ) ... results of the Phase 3 Rocket 1 trail of ... to meet its end points, compelling data from the ... studies. An analyst report on AERI that ... analyst summary, valuation, and recommendation can be viewed by ...
Breaking Medicine Technology:Institute for Healthcare Advancement Announces 2015 Award Winners 2Semler Reports First Quarter 2015 Financial Results 2Semler Reports First Quarter 2015 Financial Results 3Semler Reports First Quarter 2015 Financial Results 4Semler Reports First Quarter 2015 Financial Results 5All is Not Lost for Aerie Pharmaceuticals - VLM Research Issued by BrokerBank Securities, Inc. 2
... FARMINGDALE, N.Y., Feb. 9, 2011 Misonix, Inc. ... company that designs, manufactures, and markets innovative, therapeutic, ... neurosurgery, laparoscopic surgery, and other surgical and medical ... fiscal quarter and six months ending December 31, ...
... SAN FRANCISCO, Feb. 9, 2011 SYNARC, ... to the pharmaceutical and biotechnology industries, announced today that ... and marketing efforts in support of the company,s rapidly ... Ciaran Cooper, a pioneer in the clinical trials ...
Cached Medicine Technology:Misonix Reports Second Quarter and Six Months Fiscal 2011 Financial Results 2Misonix Reports Second Quarter and Six Months Fiscal 2011 Financial Results 3Misonix Reports Second Quarter and Six Months Fiscal 2011 Financial Results 4Misonix Reports Second Quarter and Six Months Fiscal 2011 Financial Results 5Misonix Reports Second Quarter and Six Months Fiscal 2011 Financial Results 6SYNARC Appoints Ciaran Cooper as Vice President, Business Development 2
... VasoSeal VHD was ... rapidly stop bleeding after ... and radiology procedures. It ... sealing device approved for ...
... collagen hemostat. FirstStop is a non-friable, non-woven ... characteristics. It can easily be cut to ... FirstStop products are not dispersed when wet ... hemostasis is achieved. As the collagen forms ...
InterVascular HemaPatch product line offers the vascular surgeon a range of collagen coated patches in a range of larger sizes angioplasty, or profundaplasty procedures without suture hole bleeding. ...
The VasoSeal Low Profile device is designed for smaller sheath angiography procedures. VasoSeal Low Profile. Seal your arterial punctures with confidence....
Medicine Products: