Navigation Links
New Treatment Shows Promise for Excessive Drinking
Date:6/10/2008

Boosting brain protein in animal study cut desire, relapse in as little as 10 minutes

TUESDAY, June 10 (HealthDay News) -- A new treatment that reduces excessive drinking and prevents drinking relapse proved successful in tests on rats, a new study finds.

The treatment involves increasing levels of a brain protein called glial cell-derived neurotrophic factor (GDNF) -- also being looked at as a treatment for Parkinson's disease. The researchers also pinpointed the site in the brain where GDNF acts to control drinking.

In addition, the treatment didn't block other normal pleasure-seeking behaviors (such as craving sweets), a common problem with drugs developed to treat alcoholism.

In this study, rats were conditioned for two months to seek alcohol. The researchers then injected GDNF into a brain region called the Ventral Tegmental Area (VTA), which is believed to be strongly involved in drug-seeking behavior. The rats' desire to drink alcohol decreased significantly within as little as 10 minutes, and the effect lasted at least three hours.

But the rats still wanted to drink sugar water after the injections of GDNF, which shows that increased levels of GDNF didn't decrease this pleasure-seeking behavior.

In another part of the study, the researchers trained rats to desire alcohol and then took it away from them. When alcohol was reintroduced, the rats started drinking the same amount as before. But when they were treated with GDNF, they lost their taste for alcohol.

The study was published in this week's issue of the Proceedings of the National Academy of Sciences.

"Alcoholism is a devastating and costly psychiatric disease with enormous socioeconomic impact. There is tremendous need for therapies to treat alcohol abuse," study senior author Dorit Ron, principal investigator at the University of California, San Francisco-affiliated Ernest Gallo Clinic and Research Cen
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. The Monoclonal Antibodies Drug Market for the Treatment of Cancer Will More Than Double to $16.7 Billion By 2016
2. Treatment at an AASM accredited sleep center improves long-term CPAP compliance
3. TB treatment for the elderly likely requires a boost to immune response
4. Botox and Restylane Not A Destination or Spa Treatment
5. WHO Report Says 9.7 Million at Risk of Death from AIDS Today; AHF Renews Call for US Congress to Commit to Scale up Treatment to Seven Million Lives
6. Celebrate Swedish Breaks Record Again; Helps Launch Center for Advanced Brain Tumor Treatment
7. AstraZeneca submits an sNDA for Symbicort for treatment of asthma in children as young as 6
8. New Program/Website Targets Jewish Children, Teens, and Adults Suffering from the Impact of Childhood Maltreatment
9. Treatment improves walking ability of Parkinsons patients
10. New model predicts whether patients will be free of renal cancer 12 years after initial treatment
11. Five-Year Cancer Survivors Will Celebrate Life(R) at Cancer Treatment Centers of America(R)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... Ohio, June 5 Cardinal Health will hold an ... 8:30 a.m. EDT. The sole purpose is to discuss ... for Cardinal Health and CareFusion as standalone entities. , ... will host the session and will explain pro forma ...
... have improved in Swedish middle-aged women during the past ... increased significantly. These are the of a thesis ,presented ... The study is part of the Prospective Population Study ... at the end of the 1960s, when 1,462 middle-aged ...
... , FT. MYERS, Fla., June 5 /PRNewswire-FirstCall/ -- ... announced that it will present at the Fifth Annual ... Monday, June 8, 2009 at the Seminole Hard Rock ... President and Chief Scientific Officer will give a presentation ...
... To Multi-Billion Dollar Home Skin Care Market , , ... PMTI ), a leading researcher and developer of ... become the first company to receive a 510(k) over-the-counter (OTC) ... for a new, patented, home use, laser device for the ...
... Dad consume has little effect on children,s choices, study ... eating habits don,t seem to influence their children,s food ... suggests. , "We found that the resemblance in dietary ... senior author Dr. Youfa Wang, an associate professor of ...
... , 70 Years of Service Excellence and Innovation Leads ... to Improve Patient Care and Increase Productivity , ... interoperability of disparate healthcare IT systems, announced today that ... Radiology Associates of the Fox Valley (RAFV) of Neenah, ...
Cached Medicine News:Health News:Cardinal Health Investor and Analyst Advisory 2Health News:Middle-aged women experience more stress but have lower blood pressure 2Health News:NeoGenomics to Present at Noble Financial's 5th Annual Equity Conference on Monday, June 8th 2Health News:Palomar Receives FDA Over-The-Counter Clearance for a Home Use Wrinkle Removal Laser Device 2Health News:Palomar Receives FDA Over-The-Counter Clearance for a Home Use Wrinkle Removal Laser Device 3Health News:Palomar Receives FDA Over-The-Counter Clearance for a Home Use Wrinkle Removal Laser Device 4Health News:Parental Eating Habits Don't Rub Off on Kids 2Health News:Compressus Initiates Enterprise Workflow Management Implementation at Radiology Associates of Fox Valley 2Health News:Compressus Initiates Enterprise Workflow Management Implementation at Radiology Associates of Fox Valley 3
(Date:12/17/2014)... 2014  Northstar Global Business Services, Inc. (OTCPink:MDIN) ... has made their final decision and has determined ... stock effective December 15, 2014, and has resumed ... and book entry transfer services. All deposit restrictions have ... again fully "DTC Eligible", and has resumed electronic ...
(Date:12/17/2014)... 2014  Beamz Interactive, Inc. (OTCQB: BZIC), a ... announced that it has signed an agreement with ... of innovative prosthetic, orthotic and assistive technology products ... agreement, RSL Steeper will promote and supply the ... use within UK residential care facilities through its ...
(Date:12/17/2014)... ANGELES , Dec. 17, 2014  ImmunoCellular ... the US Patent and Trademark Office (USPTO) has ... ICT-107, a dendritic cell-based immunotherapeutic vaccine targeting six ... The claims of US Patent No. 8,871,211, which ... neural cancer by administering a dendritic cell composition ...
Breaking Medicine Technology:Northstar announces that the DTC chill on MDIN has been officially lifted 2Northstar announces that the DTC chill on MDIN has been officially lifted 3Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 2Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 3ImmunoCellular Therapeutics Announces Issuance of Key Patent For ICT-107 Cancer Vaccine 2
... 2011 Healthpoint today announced the launch of a ... Biotherapeutics, along with an updated brandmark and corporate tagline, ... is designed to communicate the company,s commitment to scientific ... contribute to improved outcomes and quality of life for ...
... Md., Feb. 23, 2011 The Cystic Fibrosis Foundation and ... development that targets the defective protein that causes cystic fibrosis, ... The trial was designed to evaluate patients age ... a CF mutation called G551D. The study included 161 patients ...
Cached Medicine Technology:Healthpoint Launches New Corporate Identity 2Healthpoint Launches New Corporate Identity 3Phase 3 Study of VX-770 Shows Marked Improvement in Lung Function Among People with Cystic Fibrosis with G551D Mutation 2Phase 3 Study of VX-770 Shows Marked Improvement in Lung Function Among People with Cystic Fibrosis with G551D Mutation 3
PremierEdge™ Implant Knives....
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Medicine Products: