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New Treatment Now Available That Extends Life in Men with Highly Advanced Prostate Cancer
Date:12/9/2013

Philadelphia, PA (PRWEB) December 09, 2013

Men suffering from highly advanced prostate cancer have new hope for longer survival times based on a recent clinical trial, the interim results of which were just announced by the National Institutes of Health. The findings suggest that physicians can immediately consider changing their clinical practice from the use of hormone therapy alone to a combination of chemotherapy and hormone therapy to improve survival.

Designed and conducted by the ECOG-ACRIN Cancer Research Group as part of the National Clinical Trials Network sponsored by the National Cancer Institute, part of the NIH, the clinical trial provides insight about the use of chemotherapy earlier in the course of prostate cancer treatment than is typically done in current clinical practice. Docetaxel, a US Food and Drug Administration-approved chemotherapy drug, was administered in combination with androgen deprivation therapy (ADT) when a man presented with advanced prostate cancer—cancer that had spread (metastasized). The trial showed that early application of both therapies is more effective than hormone therapy alone and is associated with an improvement in overall survival.

“Using the combination of docetaxel and ADT as initial treatment—and not waiting until progression on the ADT—has the potential to extend the life of men suffering from advanced prostate cancer,” said lead investigator Christopher J. Sweeney, MBBS, a Medical Oncologist at the Dana Farber Cancer Institute and Associate Professor of Medicine at the Harvard Medical School, both in Boston, MA.

The clinical trial enrolled 790 men with advanced prostate cancer that was hormone-sensitive (meaning prostate cancer growth depended on hormones) between July 2006 and November 2012, and
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