Navigation Links
New Therapies Offer Insight Into Battling Deadly Melanomas
Date:1/31/2011

By Amanda Gardner
HealthDay Reporter

MONDAY, Jan. 31 (HealthDay News) -- Two new studies report some success in treating a particularly stubborn form of cancer: melanoma, a deadly malignancy that first appears in the skin before frequently spreading to other parts of the body.

The first study, appearing in the Jan. 31 issue of the Journal of Clinical Oncology, used genetically engineered immune cells from the patient to fight off the cancer cells.

The second study, appearing in this week's issue of the Proceedings of the National Academy of Sciences, targeted a subgroup of cancer cells thought to be primarily responsible for metastasis -- the spread of cancer.

The technique used in the first study, which included 17 patients, is called "adoptive immunotherapy."

Basic immunotherapy involves "removing [immune] cells from the patients, growing them to large numbers, then giving them back," explained study senior author Dr. Steven A. Rosenberg, chief of surgery at the U.S. National Cancer Institute.

The researchers went one step further by modifying the cells to recognize and bind to a specific protein on cancer cells, NY-ESO-1.

"We genetically engineered them to recognize the cancer," said Rosenberg. "Basically we created a new drug for every patient, using their own cells to treat them."

Forty-five percent of melanoma patients in the study responded to the therapy, as did about two-thirds of patients with a rare soft-tissue cancer known as synovial cell sarcoma, which attacks muscle, fat, blood tissue and tissue lining the joints. Two of the 11 melanoma patients saw their cancer disappear for more than a year.

The synovial cell sarcoma findings were significant, said Rosenberg, because "this is the first time we've [successfully] used gene therapy for a solid cancer other than melanoma."

Also, the NY-ESO-1 antigen is found in many other cancers, including breast, p
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Many U.S. Hospices Provide Alternative Therapies: Report
2. Link between signaling molecules could point way to therapies for epilepsy, stroke, other diseases
3. Many Brain Tumor Patients Turn to Alternative Therapies
4. John Theurer Cancer Center presents studies on promising therapies for aggressive blood cancers
5. New therapies and gene target advance the treatment and understanding of hard-to-treat leukemias
6. Alternative therapies may leave asthmatics gasping
7. Certain cancer therapies success depends on presence of immune cell, Stanford study shows in mice
8. Certain new therapies for age-related eye disease do not appear to increase heart risks
9. Governments should pay for smoking cessation therapies
10. Snake venom studies yield insights for development of therapies for heart disease and cancer
11. Program focuses on anti-cancer stem cell therapies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Therapies Offer Insight Into Battling Deadly Melanomas
(Date:9/19/2014)... AZ (PRWEB) September 19, 2014 Hastings and ... 30 years in the industry, announces a record number of ... handles a wide variety of serious injury cases as well ... along with dog bite related accident cases and others. Having ... and Hastings has stood the test of time when it ...
(Date:9/19/2014)... U.S. military troops deployed to sunny climates may have ... new study. Many returning troops reported getting ... military personnel developed blisters on their skin or noticed ... their moles since being deployed overseas. All of ... the study authors noted. "The past decade of ...
(Date:9/19/2014)... HealthDay Reporter THURSDAY, Sept. 18, ... and family conflicts before surgery may face a higher ... suggests. Investigators found that patients with a so-called ... greater risk for complications compared to those with a ... known that patient quality of life is a complex ...
(Date:9/19/2014)... (PRWEB) September 19, 2014 "I have ... getting wrinkles due to stretching the skin around my ... Ala. "This inspired me to design a more convenient ... CONTACT LENS SYSTEM provides a quicker, easier, more sanitary ... need to perform this task manually, saves time and ...
(Date:9/19/2014)... Jacksonville,s campus of Mayo Clinic have discovered a defect ... both overproduction of toxic protein in the brains of ... of communication between neurons both significant contributors to ... online issue of Neuron , offers ... "may rejuvenate or rescue this pathway," says the study,s ...
Breaking Medicine News(10 mins):Health News:Hastings And Hastings Announces a Record Number of Visitors to Its New Phoenix Personal Injury Website 2Health News:Some U.S. Troops May Face Greater Skin Cancer Risk 2Health News:Family Squabbles Can Derail Recovery From Cancer Surgery 2Health News:Family Squabbles Can Derail Recovery From Cancer Surgery 3Health News:Mayo researchers reveal pathway that contributes to Alzheimer's disease 2
... Swven staff at RMIT University in Melbourne, working just meters below ... with brain tumors. // ,Following the report of these ... building and plans to begin immediate health and safety testing. ... top two floors of the Bourke St building and have developed ...
... Parliament says that almost a thousand people end up in ... report, which was available in the parliament yesterday, showed that ... year." This was indeed a massive jump when compared with ... is growing at an alarming rate, so we need action ...
... According to a recent study conducted by the researchers at ... one in seven East Asian immigrants are carriers// of the ... liver cancer and cirrhosis. But it is surprising to know ... infected. Three-quarters of these people who are infected had no ...
... Health workers by the Ontario government, to beat a possible ... from critics // , who see this is politically motivated ... The opinion doing the rounds is that the kits ... ,According to health minister George Smitherman, 15,000 emergency kits will ...
... have developed ,the first knee replacement shaped to fit ... U.S. Food and Drug Administration, and will be distributed ... Aaron G. Rosenberg and Dr. Richard A. Berger, orthopedic ... sought to address shape-related differences of a woman’s knee. ...
... has lost a third of their value on Wednesday after ... treatment against the hepatitis C virus. // ... percent, to $4.83, in the heavy morning trade on the ... that the results came from the second stage of a ...
Cached Medicine News:Health News:RMIT Staff Diagnosed with Brain Tumors 2Health News:East Asian Immigrants Bring Hepatitis to New York 2Health News:Shapelier Knee Replacements for Women 2Health News:Shapelier Knee Replacements for Women 3Health News:Shapelier Knee Replacements for Women 4
(Date:9/19/2014)... 19, 2014 The Parenteral Drug Association (PDA) ... post-approval changes protocols. The new initiative ... expressed by industry participants and regulatory authority representatives at ... in Washington, DC . Representatives of ... for the workshop. Attendees indicated openness to engaging regulators ...
(Date:9/19/2014)... , September 19, 2014 ... ) has announced the addition of the ... report to their offering.      ... have been broadly classified into wide categories ... used for the treatment of different gynecological ...
(Date:9/19/2014)... , Sept. 19, 2014  For Cloud Pharmaceuticals, ... design and development, partnering is an integral part ... to design new drugs and identify early stage, ... to further their development. The company also partners ... support this business model, Cloud Pharmaceuticals will be ...
Breaking Medicine Technology:PDA Launches Effort to Harmonize Global Post-Approval Changes Protocols 2Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 2Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 3Cloud Pharmaceuticals Announces Partnering Sessions and Presentation Schedule 2
... 15, 2012  IntelligentMDx (IMDx) announced today that it has ... in vitro diagnostic test designed for the rapid ... use in screening pregnant women and those in labor ... responsible for life-threatening bacterial infections in newborns, including sepsis, ...
... YORK, May 15, 2012 ... market research report is available ...   ... Trends, Marketing Spend and Sales ...
Cached Medicine Technology:IntelligentMDx Announces CE-Marking of a new high-throughput test for Group B Streptococcus intended to improve women's health and prenatal care 2Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 2Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 3Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 4Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 5Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 6Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 7Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 8Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 9Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 10Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 11Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 12Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 13Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 14Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 15Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 16Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 17Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 18
... features including aspiration holes and additional ... procedures requiring precise dissection with decreased ... suction demands. ,Flexible design options ... nonretractable electrodes and multiple tip designs. ...
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
... Instruments incorporate a layered design unique in ... monitored to prevent stray electrosurgical burns along ... insulation failure or capacitive coupling; a well-documented ... into all AEM Instruments provides a neutral ...
Medicine Products: