Navigation Links
New Therapies Offer Insight Into Battling Deadly Melanomas
Date:1/31/2011

By Amanda Gardner
HealthDay Reporter

MONDAY, Jan. 31 (HealthDay News) -- Two new studies report some success in treating a particularly stubborn form of cancer: melanoma, a deadly malignancy that first appears in the skin before frequently spreading to other parts of the body.

The first study, appearing in the Jan. 31 issue of the Journal of Clinical Oncology, used genetically engineered immune cells from the patient to fight off the cancer cells.

The second study, appearing in this week's issue of the Proceedings of the National Academy of Sciences, targeted a subgroup of cancer cells thought to be primarily responsible for metastasis -- the spread of cancer.

The technique used in the first study, which included 17 patients, is called "adoptive immunotherapy."

Basic immunotherapy involves "removing [immune] cells from the patients, growing them to large numbers, then giving them back," explained study senior author Dr. Steven A. Rosenberg, chief of surgery at the U.S. National Cancer Institute.

The researchers went one step further by modifying the cells to recognize and bind to a specific protein on cancer cells, NY-ESO-1.

"We genetically engineered them to recognize the cancer," said Rosenberg. "Basically we created a new drug for every patient, using their own cells to treat them."

Forty-five percent of melanoma patients in the study responded to the therapy, as did about two-thirds of patients with a rare soft-tissue cancer known as synovial cell sarcoma, which attacks muscle, fat, blood tissue and tissue lining the joints. Two of the 11 melanoma patients saw their cancer disappear for more than a year.

The synovial cell sarcoma findings were significant, said Rosenberg, because "this is the first time we've [successfully] used gene therapy for a solid cancer other than melanoma."

Also, the NY-ESO-1 antigen is found in many other cancers, including breast, p
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Many U.S. Hospices Provide Alternative Therapies: Report
2. Link between signaling molecules could point way to therapies for epilepsy, stroke, other diseases
3. Many Brain Tumor Patients Turn to Alternative Therapies
4. John Theurer Cancer Center presents studies on promising therapies for aggressive blood cancers
5. New therapies and gene target advance the treatment and understanding of hard-to-treat leukemias
6. Alternative therapies may leave asthmatics gasping
7. Certain cancer therapies success depends on presence of immune cell, Stanford study shows in mice
8. Certain new therapies for age-related eye disease do not appear to increase heart risks
9. Governments should pay for smoking cessation therapies
10. Snake venom studies yield insights for development of therapies for heart disease and cancer
11. Program focuses on anti-cancer stem cell therapies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Therapies Offer Insight Into Battling Deadly Melanomas
(Date:7/30/2015)... ... July 30, 2015 , ... According ... do not find a complete removable denture acceptable. The demand for dental implants ... that incorporate less expensive, immediate loading techniques will have the ability to offer ...
(Date:7/30/2015)... ... ... many people place a lot of focus on the different types of food that need to ... key component to successful weight gain is knowing when to eat so that the ... gives three tips on when to eat to gain weight. , The first thing to ...
(Date:7/30/2015)... (PRWEB) , ... July 30, 2015 , ... PeopleKeys, a ... air a “Managing Stress: Train the Trainer” webinar. The webinar, the newest installment in ... August 13th, 2015. , The Managing Stress: Train the Trainer webinar is intended for ...
(Date:7/29/2015)... ... July 30, 2015 , ... Macro Wealth Management (MWM) ... the Smile for a Lifetime program by encouraging their clients to donate their MWM ... MWM Presidents Dr. Mart McClellan and Tim Streid, who see charitable giving as an ...
(Date:7/29/2015)... Plano, TX (PRWEB) , ... July 30, 2015 ... ... best content available for their clients, BOC approved provider of online continuing ... six new course offerings to their exclusive Andrews Research and Education Sports Medicine ...
Breaking Medicine News(10 mins):Health News:Chicago Implant Dentist/Implantologist Dr. Irfan Atcha Speaks to Local Dentists about Advances in Dental Implants in August. 2Health News:Chicago Implant Dentist/Implantologist Dr. Irfan Atcha Speaks to Local Dentists about Advances in Dental Implants in August. 3Health News:CB-1 Weight Gainer Gives Three Tips on When to Eat to Gain Weight 2Health News:CB-1 Weight Gainer Gives Three Tips on When to Eat to Gain Weight 3Health News:PeopleKeys to Air “Managing Stress: Train the Trainer” DISC Webinar 2Health News:Smile for a Lifetime (S4L) Partners with Macro Wealth Management (MWM) Helping More Children Get Braces 2Health News:Elite Online Continuing Education Provider Adds Six New Athletic Training Courses to Exclusive Andrews Research and Education Sports Medicine Series 2Health News:Elite Online Continuing Education Provider Adds Six New Athletic Training Courses to Exclusive Andrews Research and Education Sports Medicine Series 3
... physical exercise has been shown to trigger migraine headaches among ... well tolerated by patients. The findings show that the program ... The study is published in Headache: The Journal of ... sample of migraine sufferers who were examined before, during and ...
... 26 Results of a Mayo Clinic study ... predictive" of a major cardiac event, such as a heart ... or moderate risk, according to researchers.The study will be presented ... American College of Cardiology Annual Scientific Session in ...
... 26 While it is touted as a major tool ... has serious implications for Americans, health privacy. The Institute ... (H.R. 1, Public Law No. 111-5) weakens individuals, control over ... stimulus law plans for every American to use an electronic ...
... Mylan Inc. (Nasdaq: MYL ) today ... Matrix Laboratories Limited from minority shareholders pursuant to a ... owns approximately 71.2% of Matrix and controls more than ... transaction is anticipated to be accretive to Mylan,s 2009 ...
... stronger than current imaging, researchers say , , THURSDAY, March ... resonance imaging (MRI) can better detect molecular changes inside ... cancer, say Duke University chemists. , MRI uses hydrogen ... magnetic pulses and radio waves, but the process requires ...
... Transdermal delivery of estrogen therapy available by prescription ... (VTE), or blood clotting, in postmenopausal patients when compared ... study was conducted by researchers at NYU Langone Medical ... Menopause : The Journal of the North ...
Cached Medicine News:Health News:Mayo Study Shows Simple Finger Device May Help Predict Future Heart Events, Such as Heart Attack 2Health News:Mayo Study Shows Simple Finger Device May Help Predict Future Heart Events, Such as Heart Attack 3Health News:Economic Stimulus Law Weakens Americans' Control Over Personal Health Information 2Health News:Mylan Announces Intention to Purchase Remaining Interest in Matrix Laboratories and Delist Matrix from Indian Stock Exchanges 2Health News:Mylan Announces Intention to Purchase Remaining Interest in Matrix Laboratories and Delist Matrix from Indian Stock Exchanges 3Health News:New study suggests Rx estrogen delivery through the skin may show safety benefits as opposed to oral delivery 2
(Date:7/30/2015)... July 30, 2015 Tissue ... the regenerative medical devices company, announces that it ... wound care market as Tissue Regenix Wound Care ... Medicare administrator, First Coast Service Options Inc. ("First ... , Puerto Rico and ...
(Date:7/29/2015)... , July 30, 2015 ... Guidance   for ... Core Earnings and Core ... Highlights of Q1 results  ... Underlying core earnings and underlying core EPS were flat, year-to-year , ...
(Date:7/29/2015)... , July 29, 2015 Insulet Corporation (NASDAQ: ... technology with its OmniPod ® Insulin Management System, ... ended June 30, 2015. The Company also announced that ... quarter financial results and conference call from Thursday, July ... Second Quarter Revenue Highlights: , ...
Breaking Medicine Technology:Tissue Regenix Group plc: First Coast Service Options Inc. Approves Medicare Coverage for DermaPure 2Tissue Regenix Group plc: First Coast Service Options Inc. Approves Medicare Coverage for DermaPure 3Takeda Reports 1st Quarter Results of FY2015 with Underlying Revenue Growth of +6.1% 2Takeda Reports 1st Quarter Results of FY2015 with Underlying Revenue Growth of +6.1% 3Takeda Reports 1st Quarter Results of FY2015 with Underlying Revenue Growth of +6.1% 4Takeda Reports 1st Quarter Results of FY2015 with Underlying Revenue Growth of +6.1% 5Insulet Reports Preliminary Second Quarter 2015 Revenue Results 2Insulet Reports Preliminary Second Quarter 2015 Revenue Results 3Insulet Reports Preliminary Second Quarter 2015 Revenue Results 4Insulet Reports Preliminary Second Quarter 2015 Revenue Results 5
... and Physician,Reports that Children with Autism Spectrum ... Fever, BALTIMORE, Dec. 3 Over ... observed that the behaviors of children with,autism ... rather,dramatically, during a fever. Longer concentration spans, ...
... World AIDS,Day 2007, CHF International is honoring the struggle ... HIV/AIDS, but calls for greater,international support of grassroots, community-based ... decades, international assistance has made a marked,impact in helping ... means that more people are able to treat their ...
Cached Medicine Technology:Study Finds Fever may Lead to Improved Behavior in Children with Autism Spectrum Disorders 2Study Finds Fever may Lead to Improved Behavior in Children with Autism Spectrum Disorders 3Study Finds Fever may Lead to Improved Behavior in Children with Autism Spectrum Disorders 4On World AIDS Day, CHF International Calls for Community Mobilization and Local Capacity Building to Fight HIV/AIDS 2On World AIDS Day, CHF International Calls for Community Mobilization and Local Capacity Building to Fight HIV/AIDS 3
The 3.0 mm Cannulated Screw can be used with or without threaded washer. Uses 1.1 mm threaded or non-threaded guide wire. , ,The Threaded Washer provides a recessed internal buttress which allows the...
... BIAX Total Wrist System was the first wrist ... normal wrist. Since then it has become the ... , ,During total wrist replacement surgery, doctors remove ... joint replacement implant in place of the damaged ...
... a simple, effective instrument to grasp soft tissue ... and loop. The grasping function of the instrument ... and precisely place a stitch up to 1 ... all in one quick step. The sterile, single ...
... Punch Forceps provide superior tissue excision with ... an aggressive tooth pattern to capture loose ... a unique stress pin buffering system to ... use, the stress pin buffering system applies ...
Medicine Products: