Navigation Links
New Therapies Could Change Organ Transplants
Date:1/23/2008

ricking" the immune system into thinking the organ had come from the recipient. Both procedures also involved transplanting donor stem cells into the recipient.

"The ability to achieve tolerance in what's called stable chimerism [when donor cells are present in the recipient] in patients has been postulated since the 1960s," said Dr. Roy Smythe, chairman of surgery at Texas A&M Health Science Center School of Medicine. "It's really been a 'gee whiz' thing for the last 30 years. . . This is proof of principle in human beings, which is a big deal."

But, Smythe noted, forcing tolerance in transplant patients poses a fair bit of danger. "It's going to be tough at first, but the likelihood is, in the next 10 years, we will find less injurious and dangerous ways to prepare people for tolerance, so eventually it will be a safe thing to do. There's a long road to hoe yet, but it's going to happen. It's very exciting."

In the Sachs study, four of five patients who had HLA-mismatched kidney transplants were able to stop taking immunosuppressive drugs nine to 14 months after the transplant. Kidney function has stayed stable for up to 5.3 years since the transplantation.

HLA refers to human leukocyte antigens, which is one of the primary ways donors and recipients are matched. HLAs, found on the surface of virtually all cells, help tell the difference between normal body tissue and foreign substances.

All patients first underwent a procedure to partially destroy their bone marrow and reduce the level of T-cells (the part of the immune system most responsible for organ rejection). The bone marrow eventually regenerated and produced new immune cells which accepted the new organ.

The procedure had already been successfully performed on matched transplants.

Strober and his colleagues altered the immune system of a man who had received a closely matched kidney from his brother. The man has lived without immu
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Pipeline for New Obesity Therapies is Focus of New Report
2. MIT: Stem-cell therapies for brain more complicated than thought
3. Many prostate cancer patients receive improper or mismatched therapies
4. Thomson Scientific Publishes Who Is Making The Biggest Splash? - a Quarterly Review of Scientific Literature on Drugs and Therapies From July - September 2007
5. Telomerase enzyme structure provides significant new target for anti-cancer therapies
6. Studies attribute recent increase in multiple myeloma survival to novel therapies
7. Turning Pointe Therapeutic Riding Recognized for Excellence in Providing Equine-Assisted Therapies to People with Disabilities
8. Emerging therapies with a focus on Asian populations mark the AACR Centennial Conference
9. Mayo researchers: complementary therapies help patients recover after heart surgery
10. Video and Photo: Tasigna(R) Receives US Approval Providing New Hope to Chronic Myeloid Leukemia Patients With Resistance or Intolerance to Existing Therapies
11. Comprehensive Review of Cancer Immnunotherapies Published By CEL-SCI
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Therapies Could Change Organ Transplants
(Date:12/17/2014)... This prestigious award is given ... made outstanding and innovative contributions to the physical ... private practice physical therapy by the Private Practice ... On behalf of Performance Physical Therapy, Michelle Collie ... Performance accepted the award at the Private Practice, ...
(Date:12/17/2014)... December 17, 2014 Now in its ... the best of the best in senior living and ... only given to communities and agencies that have received ... site. Of the nearly 100,000 providers currently listed on ... of the SeniorAdvisor.com Best of 2015 Awards are located ...
(Date:12/17/2014)... 16, 2014 (HealthDay News) -- Poor students get more fruits ... new study finds. But, the opposite is true for ... fruits and vegetables at school may give a healthy boost ... no matter what the family income level, students all ate ... study found. The study was published recently in the ...
(Date:12/15/2014)... Grants Pass, OR (PRWEB) December 15, 2014 ... factors perceived by United States women as impacting skin ... – the “Four C’s of skin care.” Water and ... the conclusions in a recent article describing the survey ... her experience, every item in every category discussed would ...
(Date:12/15/2014)... SIMpalm, a leading mobile app ... iPhone for its client, which allows users to keep ... specialized in finding the right wine. At the ... combined sensory, chemistry and wine information. All this information ... fingerprint.” Those wines that are close counterparts to one ...
Breaking Medicine News(10 mins):Health News:Performance Physical Therapy Awarded with Jayne L. Snyder Private Practice of the Year 2014 2Health News:The Inn at Willow Falls - Crest Hill, IL Wins 2015 Best of Assisted Living Award from SeniorAdvisor.com 2Health News:The Inn at Willow Falls - Crest Hill, IL Wins 2015 Best of Assisted Living Award from SeniorAdvisor.com 3Health News:Poor Students Eat Healthier Foods at School, Study Finds 2Health News:Water and health advocate Sharon Kleyne adds a “W” for fresh water to “four C’s of skin care” 2Health News:Water and health advocate Sharon Kleyne adds a “W” for fresh water to “four C’s of skin care” 3Health News:Use WinMatch Connect App to Keep Track of Wines You Like 2
... banned the use of vibrating condoms, saying it goes ... Limited (HLL) introduced the item throughout the country about ... Hindu hardliners described the condom was a sex toy ... protest, the ruling Bharatiya Janata Party (BJP) banned the ...
... where the potentially lethal H5N1 strain of bird flu was ... ,"All the turkeys on the farm have been ... in the area, around 1,000 birds in all," Czech veterinary ... completed today (Friday)," he added. ,The H5N1 strain of ...
... a grisly state-run Baghdad orphanage this week revealed the ... most vulnerable citizens. ,With four years of ... have begun providing vital social services at their own ... ,The images of the inside of the al-Hanan ...
... patented the technology of making new transgenic mushrooms, which ... production of commercially valuable proteins or useful human ... team of researchers including Charles Peter Romaine and Xi ... the study, scientists developed a technique to genetically modify ...
... Three Gorges Dam project across the Yangtze River will ... largest dam is already changing the local weather, claim ... data suggest that the reservoir is cooling the Yangtze ... ,Climate modeler Liguang Wu of NASA's Goddard Space ...
... mid- and upper-latitude regions are playing a smaller role ... to a study appearing in this week's issue of ... so-called missing carbon sink, concludes that intact tropical forests ... from the atmosphere, thereby partially offsetting carbon entering the ...
Cached Medicine News:Health News:Iraq's Orphans Left to the Kindness of Strangers 2Health News:Iraq's Orphans Left to the Kindness of Strangers 3Health News:New Transgenic Mushrooms Raise Hope for Mass Production of Human Drugs 2Health News:China's Three Gorges Dam Changing Local Weather: Scientists 2Health News:Northern Forests Less Effective Than Tropical Forests in Reducing Global Warming 2Health News:Northern Forests Less Effective Than Tropical Forests in Reducing Global Warming 3
(Date:12/17/2014)... -- , The new Dompé ... information concerning the biopharmaceutical Group,s national and international clinical research ... the recently launched institutional website that is receiving accolades from ... a new chapter in the fascinating story of Drug Discovery ... panoramic hub on the world of clinical research, ranging from ...
(Date:12/17/2014)... 2014 PCCA received the Autism Hope ... ) program seal for best practices in meeting ... medical practices, materials and goods that meet strict ... Children affected by autism often have unique physical ... ingredients found in food and medicine – for ...
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/ms3j8c/cardiac ) has announced the addition ... and Forecasts, 2012-2018"  report to their offering. Global ... 2016. The North America accounts ... Europe claims approximately 25% (2018). ...
Breaking Medicine Technology:Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 2Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 3Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 3Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 2Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 3Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 4
... EXTON, Pa., Dec. 9, 2010 Physiotherapy Associates, the ... new MS Specialty Program, which includes physical therapy services ... or alleviate the symptoms of MS for patients, available ... States. "Our new MS Specialty Program will ...
... Ambry Genetics, a global leader in genomic services ... that it has officially launched their Illumina HiSeq 2000 ... early adapter of Illumina sequencing systems since 2007 and ... (Logo:   http://photos.prnewswire.com/prnh/20090428/LA06744LOGO ) "We,ve ...
Cached Medicine Technology:Physiotherapy Associates Announces New Multiple Sclerosis Specialty Treatment Program 2Ambry Genetics Launches Illumina HiSeq 2000 Next Generation Sequencing Services 2
Inquire...
QC HGB is an assayed quality control material for Hemocue analyzers. This control is a solution of stabilized human red cells and is available in 3 levels for monitoring analyzer performance at sever...
... a state of the art software package designed ... Optical Laboratory. Designed by a lens manufacturer with ... polycarbonate lenses, Optifacts is designed to help you ... not the way the software dictates., ,Designed specifically ...
VertiGraft allografts for spine surgery deliver the strength adn performance you demand in your procedures and they are backed by quality and safety standards that are unmatched in the industry....
Medicine Products: