Navigation Links
New Test May Help Kidney Transplant Patients
Date:1/21/2009

Carolina researchers say it could detect virus that can lead to failure,,

WEDNESDAY, Jan. 21 (HealthDay News) -- A new urine test that can detect a common cause of kidney transplant failure may help lead to better diagnosis and treatment of patients with polyomavirus nephropathy, which affects about 9 percent of kidney transplant patients.

Polyomaviruses are harmless to healthy adults but can cause serious problems for people with compromised immune systems. People having a kidney transplant take medicines to suppress their immune system to protect against organ rejection.

There are no effective treatments for polyomavirus nephropathy, so it's important to diagnose the condition as soon as possible and lower the dose of immunosuppressive drugs in hopes of allowing the immune system to eliminate the virus. Currently, doctors rely on invasive and expensive kidney biopsies to diagnose polyomavirus nephropathy, and these tests sometimes give false negative results.

The new test -- developed by Dr. Volker Nickeleit and colleagues from the University of North Carolina at Chapel Hill -- measures levels of Haufen,, a German word for the tightly clustered viral aggregates that form in the kidneys of people with polyomavirus nephropathy and are excreted in the urine.

The researchers said the test takes three hours, costs less than $400, and is easy to perform with existing laboratory equipment. When the test was used on 160 people, including 21 with early- or late-stage polyomavirus nephropathy, the researchers detected Haufen in urine samples from all 21 people with the virus but in none of the 139 study participants without the condition.

The study was published in the February issue of the Journal of the American Society of Nephrology.

"An early and accurate diagnosis of polyomavirus nephropathy will result in a better understanding of the disease and ultimately improve treatment," Nickeleit said in an American Society of Nephrology news release. "Our diagnostic test is unique and could have a tremendous clinical impact."

More information

The National Kidney Foundation has more about kidney transplant.



-- Robert Preidt



SOURCE: American Society of Nephrology, news release, Jan. 21, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Kidney, Heart Problems May Be Linked
2. Impaired kidney function raises risk of heart problems in the elderly
3. Older Women Get Fewer Kidney Transplants Than Men
4. Blackbaud to Deliver National CRM Database and Bilingual Website for The Kidney Foundation of Canada
5. Rhode Island Hospital first in US to treat kidney tumor with new device using electrical pulses
6. A Better Method of Kidney Storage
7. Simple model predicts those at risk for chronic kidney disease
8. Low Doses of Melamine Wont Harm Kids Kidneys
9. UK kidney cancer patients face toxic, out-dated treatments with little hope of change
10. Vitamin B1 could reverse early-stage kidney disease in diabetes patients
11. Understanding donor-recipient genetics could decrease early kidney transplant complications
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Test May Help Kidney Transplant Patients
(Date:2/13/2016)... ... , ... The producers of Enterprises TV are pleased to present ... world of instantaneous consumption proves very convenient for businesses. With new technologies constantly becoming ... which pollutes our air, water, and soil. It can also threaten the lives of ...
(Date:2/13/2016)... ... 13, 2016 , ... DDi , a Makro company, ... for its expertise in eClinical Solutions. DDi has built its solution competency with ... of global clients. DDi provides smarter technology for Clinical Development, Regulatory and Enterprise ...
(Date:2/12/2016)... ... February 12, 2016 , ... ... to funding innovative lymphoma research and serving the lymphoma community through a comprehensive ... members of South Florida’s philanthropic community at its 10th anniversary Fashion Luncheon on ...
(Date:2/12/2016)... ... February 12, 2016 , ... Coco Libre, the maker ... Red Carpet Events LA GRAMMY’s Style Lounge Event. Coco Libre will offer musicians and ... hydrated before the big event. The invitation-only gifting suite, held this year at the ...
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... Fisher House ... Vegas Mayor John J. Lee, Nevada Military Support Alliance president Scott Bensing, and Peggy ... at the VA Southern Nevada Healthcare System. This will be the first Fisher ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... Feb. 12, 2016   National Community Pharmacists Association ... MBA issued the following statement today in response to ... the Centers for Medicare & Medicaid Services (CMS) ... beneficiary advocates and others: patient advocacy organizations ... still reviewing the full CMS analysis. Our initial reaction ...
(Date:2/12/2016)... , Feb. 12, 2016  Diplomat Pharmacy, Inc. (NYSE: DPLO ) is pleased to ... Account Management and Payor Strategies effective Jan. 23, 2016. ... ... ... Diplomat Specialty Pharmacy ...
(Date:2/12/2016)... MONTREAL , February 12, 2016 ... sofern nicht anders vermerkt)   ... Unternehmens http://www.telestatherapeutics.com abrufbar.    ... Website des Unternehmens http://www.telestatherapeutics.com ... Inc. (TSX:TST; PNK:BNHLF) veröffentlichte heute seinen Konzernabschluss ...
Breaking Medicine Technology: