Navigation Links
New Tel Aviv University research links diabetes to cognitive deterioration
Date:3/5/2009

Blindness, renal failure, stroke and heart disease are potential complications of type 2 diabetes, which currently afflicts more than 15 million Americans. Now research from Tel Aviv University has found more worrying news ― type 2 diabetes can be a risk factor accelerating cognitive decline and dementia.

Dr. Tali Cukierman-Yaffe, a physician and researcher from TAU's Sackler School of Medicine, found that people with diabetes were 1.5 more likely to experience cognitive decline, and 1.6 more likely to suffer from dementia than people without diabetes. Her recent publication in the journal Diabetes Care suggests that higher-than-average levels of blood glucose (blood sugar) may have a role in this relationship.

Her work is part of the ongoing Memory in Diabetes (MIND) project, a sub-study of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.

First Step Towards New Treatments

"Our results send an important message to the public," says Dr. Cukierman-Yaffe. "We have shown conclusively that there is a relationship between diabetes and cognitive dysfunction. This should be known by diabetics and their doctors. Knowledge is the first step towards action.

"Intact thinking is essential for managing the disease," Dr. Cukierman-Yaffe adds.

Clinicians today work with the patient to prevent complications of diabetes. Early detection of visual problems, for example, can be treated with laser surgery if diagnosed early enough, and blindness can be avoided in some cases.

"Today, diabetes cannot be cured. We can however delay or prevent many of its complications," says Dr. Cukierman-Yaffe. "Diagnosing cognitive dysfunction at a pre-clinical stage is the first step in finding new treatment options."

A New Association with Poor Cognitive Performance

Dr. Cukierman-Yaffe's work opens a new opportunity for researchers to better understand the cognitive risks associated with diabetes and dysglycemia. She points out that diabetes, unlike other chronic disease states, is a complex disease to manage and one that requires intact cognition in the patient. As the mind starts deteriorating, so does the patient's ability to treat the diabetes effectively. Disease management can then spiral out of control.

Findings in her recent study show that in people with type 2 diabetes, higher levels of haemoglobin A1C (a measure of average blood glucose) are significantly associated with poorer performance on three cognitive tasks which require memory, speed and ability to manage multiple tasks at the same time. A higher A1C level was also associated with a lower score on a test of global cognitive function.

The results of the study suggest that lowering A1C levels could slow the accelerated rate of cognitive decline experienced by people with diabetes. However prospective studies and clinical trials are needed in order to prove this. The ongoing ACCORD-MIND study, in which study patients are followed over time and are tested three times during the trial will test the hypothesis that lowering A1C could result in improved cognitive function.


'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert

Related medicine news :

1. University of Iowa professor identifies new eating disorder
2. University of Wisconsin Hospitals and Clinics Complete System-Wide Conversion to Masimo SET Pulse Oximetry Technology
3. University of Texas Study Details Lengthy Payment Delays for Medicare Part D Prescription Drug Claims, Confirming Need for Legislative Fix
4. Tulane University to receive $14M for international HIV/AIDS program
5. University of Nevada School of Medicine Professor Confirms Accuracy Through Validation Study Using the CSI Health Station Model 6K
6. Boston University School of Medicine researcher recipient of Memory Ride Grant
7. Loma Linda University Medical Center Selects Beryl to Manage Call Center Interactions for Womens Services Programs and Departments
8. Medina General Hospital and University Hospitals Agree to Pursue Affiliation
9. J.D. Power and Associates Reports: Hackensack University Medical Center Recognized as First Hospital to Achieve Distinction for Providing an Outstanding Inpatient Experience in All Four Service Areas
10. The First Incisionless Transoral Fundoplication for Treatment of Gastroesophageal Reflux is Performed in the U.S. at Ohio State University and Oregon Health & Science University Medical Centers
11. George Mason University professor receives $2.6 million NIH grant to study Alzheimers disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ... alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with ... for the primary prevention of cardiovascular diseases during the 15th Annual Women’s ...
(Date:10/13/2017)... York, NY (PRWEB) , ... October 13, 2017 , ... ... influential people in business to advocate for action towards gender equality at their inaugural ... views from around the globe, and reached a social audience of over 3 million. ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “The Journey: From ... every danger possible to save lost souls in the Philippines. “The Journey: From the ... is a dedicated teacher of the Bible. She has taught all ages and currently ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed a ... and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been ... standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, the ... medical article to the newly revamped Cosmetic Town journal section, featuring ... transplant procedure known as Follicular Unit Extraction (FUE). , Dr. Mohebi ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... Pa. , Oct. 10, 2017   West ... in innovative solutions for injectable drug administration, today shared ... West,s ID Adapter for improving the intradermal administration of ... Fourth Skin Vaccination Summit in May 2017 by Dr. ... Lead, Polio Department, World Health Organization (WHO), and recently ...
(Date:10/4/2017)... , Oct. 4, 2017 ... single-use, self-contained, illuminating medical devices, today announced regulatory ... Health Surveillance Agency (or Agência Nacional de Vigilância ... first single-use, cordless surgical retractor with integrated LED ... optimal access, illumination and exposure of a tissue ...
(Date:10/2/2017)... , Oct. 2, 2017 The Rebound mobile ... the struggle to reverse the tide of prescription drug addiction. ... regulating their medicine intake and stepping down their dosage in ... to launch in December 2017; the first 100,000 people to ... more at http://www.rebound-solution.com/ ...
Breaking Medicine Technology: