Navigation Links
New Technology Speeds GI Disease Diagnosis
Date:5/18/2008

Tiny microscope at end of endoscope allows immediate imagery of gastrointestinal tract

SUNDAY, May 18 (HealthDay News) -- A real-time microscopic technique called confocal laser endomicroscopy (CLE) could lead to earlier diagnosis and treatment of gastrointestinal disorders such as cancer, reflux disease, and inflammatory bowel disease.

That's the conclusion of several studies to be presented May 18 at the Digestive Disease Week conference in San Diego.

CLE, which uses a tiny microscope at the end of an endoscope, effectively and immediately identifies suspicious patterns and precancerous cells and may eliminate the need for biopsies to diagnose gastrointestinal (GI) conditions, according to experts.

"Up until now, determining the condition of a patient required days or even weeks while patients waited for diagnosis; further, it has been difficult to detect subtle precancerous lesions or even areas within a large lesion, often leading to time-consuming and labor-intensive procedures as well as uncertainty about missing something important," Dr. Pankaj J. Pasricha, professor of medicine, gastroenterology and hepatology at Stanford University School of Medicine, said in a prepared statement.

"New techniques such as those discussed (at the conference) will change the way we diagnose patients, allowing us to treat them more accurately, quickly and appropriately," Pasricha said.

In one study, Johns Hopkins University School of Medicine researchers found that CLE provided an accuracy rate of 91 percent in the upper GI tract and 93 percent in the lower GI tract.

"This is a very promising technique for real-time microscopic imaging of the gastrointestinal tract," study author Dr. Kerry B. Dunbar, a fellow in the division of gastroenterology and hepatology, said in a prepared statement. "Previously, it took a few days or a week to find out a diagnosis, because we'd have to take photos and then do a mucosal biopsy. But with CLE, we can see what's going on at the time of the endoscopy and then diagnose and treat patients immediately, instead of waiting a week or more."

In another study, Dunbar and colleagues concluded that CLE was as effective as a biopsy in identifying precancerous cells in people with Barrett's esophagus, a condition that can often lead to esophageal cancer.

These findings suggest that use of CLE could reduce the number of biopsies of abnormal tissue, because doctors would be able to immediately detect the presence of precancerous cells. Patients with Barrett's esophagus can require several tissue biopsies, which are expensive, invasive and can cause bleeding, the researchers said.

The results suggest that CLE "improves diagnosis of Barrett's esophagus, and offers great promise for reducing the number of biopsies needed to look for dysplasia in the esophagus," Dunbar said.

A third study found that CLE is highly accurate in immediately distinguishing benign from precancerous polyps of the colon. Using CLE, researchers from the Mayo Clinic, in Jacksonville, Fla., were 89 percent accurate in determining the sensitivity and specificity of colon polyps. They were able to identify small benign polyps 98 percent of the time. Normally, these polyps would be removed.

"This technique will fundamentally change how the two fields (endoscopy and pathology) interact," study author Dr. Anna M. Buchner said in a prepared statement. "This procedure allows us to become endopathologists, and the result is that we will be able to better manage patients with gastrointestinal disorders."

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about digestive diseases.



-- Robert Preidt



SOURCE: Digestive Disease Week, news release, May 18, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Quantum light beams good for fast technology
2. New Smart Technology Makes Patient Data Collection Easier, More Efficient
3. Align Technology Executive to Present at Upcoming Financial Conferences
4. Pioneer Surgical Technology Hires Vice President of New Business Development
5. Purdue researchers develop technology to detect cancer by scanning surface veins
6. Creative Technology Services Enhances its Global Competitiveness with Additional Regulatory Certifications
7. University of Wisconsin Hospitals and Clinics Complete System-Wide Conversion to Masimo SET Pulse Oximetry Technology
8. Patent Reform Legislation Threatens Americas Leadership in Medical Technology Innovation
9. Stevens Health, Technology and Society roundtable: Sept. 19
10. Microbiotic technology developed for microinjection of zebrafish embryos
11. Proven Terumo Coronary Guidewire Technology Is Now Available in the United States
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional ... action towards gender equality at their inaugural Summit in New York City in June. ... a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor ... on sciatica in a new episode of "Success Files," which is an award-winning ... innovation and investigates each subject in-depth with passion and integrity. , Sciatica occurs ...
(Date:10/13/2017)... ... ... On The Brink”: the Christian history of the United States and the loss of ... William Nowers. Captain Nowers and his wife, Millie, have six children, ten grandchildren, ... Navy. Following his career as a naval aviator and carrier pilot, he spent ...
(Date:10/12/2017)... ... ... Planet Fitness, one of the largest and fastest growing franchisors and operators ... location in Covington, LA at 401 N. U.S. Highway 190, in January of 2018. ... in the Holiday Square shopping center. Its location allows it to serve both Covington ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of ... Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, ... In honor of Morris F. Collen, a pioneer in the field of medical informatics, ...
Breaking Medicine News(10 mins):
(Date:9/12/2017)... and NEW YORK , Sept. 12, 2017 ... performance ratings for global supply chains, has published the first annual edition ... CSR performance of more than 20,400 companies evaluated by EcoVadis, based on ... 2015 and 2016. ... EcoVadis Global CSR Risk & Performance Index ...
(Date:9/12/2017)... 2017  ValGenesis Inc., the global leader in ... to announce the appointment of Dr. Ajaz ... of Directors and Chairman of Advisory Board beginning ... companies to manage their entire validation lifecycle process ... this process. Furthermore, ValGenesis VLMS enables rigorous compliance, ...
(Date:9/9/2017)... Dealmed Medical Supplies, New York ... supplies, drugs, vaccines, and specialty medical products and services, ... to acquire Vantage Medical Supplies, a major distributor of ... New York . ... medical practices, will operate under the Dealmed name as ...
Breaking Medicine Technology: