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New Technique Activates Brain Neurons to Move Paralyzed Limb
Date:10/15/2008

been taught to play before the experiment began, Moritz noted.

"Once he [the monkey] was paralyzed, the only way to move his wrist was to change the activity of individual neurons in his brain, which then controlled stimulation of his muscles," Moritz said.

The researchers found that two-thirds of the neurons they tested could be used to control muscle stimulation.

"We also found that monkeys could learn very rapidly to control newly isolated neurons in order to stimulate their muscles," Moritz said. "Even neurons that were unrelated to the movement of his wrist could be brought under control and co-opted for control of the wrist muscles."

Co-author Eberhard Fetz, also a professor in the department of physiology and biophysics at the University of Washington, said during the teleconference that future work will focus on extending the time this brain-muscle interface is maintained.

This method can include several muscles and eventually groups of muscles, Fetz said. "We are thinking in terms of not just stimulating single muscles, but stimulating sites in the spinal cord that could activate muscles in a coordinated fashion," he said. "This could eventually lead to brain control of coordinated movements."

The study shows that this technology is possible, but many obstacles remain, Moritz said. "Certainly, we are several years away, if not several decades away, from this being ready for a clinical application," he said.

Paul Sanberg, director of the University of South Florida Center of Excellence for Aging and Brain Repair in Tampa, thinks that the research is promising.

"If they could overcome some of the problems of having implants in the brain over a long period and miniaturize the apparatus, it may be possible to use this technology to regain muscle movement in people," Sanberg said. "The amount of movement could be unlimited," he added.

Sanberg noted that for someone to us
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New Technique Activates Brain Neurons to  Move Paralyzed Limb
New Technique Activates Brain Neurons to Move Paralyzed Limb