Navigation Links
New TB vaccine enters clinical testing
Date:9/23/2010

ystem to elicit a greater protective response in the body.

"The TB epidemic continues to become more complex and difficult to control, especially in South Africa where resistance to available TB treatments is on the rise," said Bernard Fourie, PhD, Chief Scientific Officer of Medicine in Need and Managing Director of Mend South Africa. "The scientific community has made developing a safer and more effective TB vaccine a priority and we are pleased that there is progress in the field."

The Phase I clinical trial to test the safety of AERAS-422 will be led by Principal Investigator Daniel Hoft, MD, PhD, at Saint Louis University's Center for Vaccine Development. The trial will enroll healthy adults who have never received a vaccination against tuberculosis. Dr. Hoft's team will also conduct initial immunological assessments.

"The TB vaccine field has made tremendous progress over the past 10 years," said Daniel Hoft, MD, PhD, of the Center for Vaccine Development at Saint Louis University. "Not only is the start of the clinical trial of AERAS-422 another important benchmark in the search for more effective TB vaccines, it is also an opportunity to learn more about cellular immunity, a less well understood but critically important component of TB vaccine development."

Aeras is pursuing a TB vaccine development strategy based on a prime-boost approach that incorporates an initial BCG or recombinant BCG vaccination for infants at birth to be followed by a booster vaccine later in infancy to adolescence. In addition to AERAS-422, developed as a "prime," Aeras is also supporting the clinical development of four TB vaccine candidates designed as "boosters" in the prime-boost vaccine scenario. Two have reached the Phase IIb proof of concept stage.


'/>"/>

Contact: Annmarie Leadman
aleadman@aeras.org
240-599-3018
Aeras Global TB Vaccine Foundation
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Elderly might not benefit from TB vaccines in development
2. More Evidence That Vaccines Dont Cause Autism
3. Sizing up stockpiles of childrens vaccines
4. Pediatric vaccine stockpile policies need to be revisited, researcher says
5. Research!America releases vaccines fact sheet
6. Nations leading ID experts call for mandatory flu vaccine for all health-care personnel
7. Vaccine has cut child cases of bacterial pneumonia, says study
8. Mumps vaccine coverage should be improved, study finds
9. Survey of American women finds STD vaccine viewed positively
10. More U.S. Teens Get Recommended Vaccines
11. New human adenovirus may not make for good vaccines, after all
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... Beach, FL (PRWEB) December 15, 2014 South ... , knows that holidays can be a daze of hassle, ... slips and falls while decking halls, to burns when making ... of holiday hazards that can happen at any time. To ... pain, MD Now has made a list of helpful and ...
(Date:12/15/2014)... December 15, 2014 Health Dialog, ... announced today that it has received Patient Oriented ... (NCQA) for its Disease Management (DM) Programs for ... (COPD), coronary heart disease and diabetes. This marks ... for Health Dialog’s Disease Management (DM) Programs, reaffirming ...
(Date:12/15/2014)... The increase in prevalence of disabling hearing ... factors which is contributing to the growth in the global ... treatment of hearing loss and balance disorders are known as ... microphone, speaker and amplifier. The global market is expected to ... the period from 2014 to 2019. Some of the factors ...
(Date:12/15/2014)... 15, 2014 In support of ... attention to restrictive state laws that may have ... this important area of public health policy. , ... the Integrity of Independent Review, contends that state ... independent peer review determinations can result in subpar ...
(Date:12/15/2014)... 2014 Kenmode Precision Metal Stamping has ... Director of Quality Assurance. He brings more than ... and certifications for manufacturers in the U.S. and abroad. ... Quality Manager at Sonoco Products Company in the Protective ... and Quality Assurance Manager for Prince Industries, all in ...
Breaking Medicine News(10 mins):Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Health Dialog Receives NCQA Accreditation for Disease Management Programs 2Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 2Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 3Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 4Health News:NAIRO Calls for Higher Quality Independent Peer Review By Ending Restrictive State Laws 2Health News:Kenmode Precision Metal Stamping Appoints Abid Rashid as Director of Quality Assurance 2
... turning to massage for relief, EVANSTON, Ill., Sept. ... to massage therapy for relaxation, according to the 12th,annual ... The survey found that 59 percent of Americans are,more ... relaxation are the,top reasons Americans received their last massage. ...
... supplier of replacement medical repair parts for hospital,equipment, was ... INC 500,for healthcare. This marks the third straight year ... of the fastest growing companies in,America., "We are ... INC,magazine recognize our tremendous growth," said President & CEO ...
... Locator Available on, http://www.flucliniclocator.org, Helps People Find ... 24 The American Lung,Association is making it ... flu shot,this season with the availability of its ... public influenza vaccination clinics is now,available at ...
... the United States are highest among African Americans, but a ... incidence and death between African Americans and whites is declining. ... cases) between the races is equal, although the death rate ... , The report will be published in an upcoming ...
... are among the 31 nationwide who have received ... of Health. The awards are designed "to enable ... transform biomedical and behavioral science." , The grants, ... five years, were awarded to Yuriy Kirichok, PhD, ...
... is playing an ever smaller role in the treatment ... and safe radiation therapy techniques. Progress in radiation technology ... This is according to Professor Freek Beekman, who will ... on Wednesday, 24 September. , In his inaugural ...
Cached Medicine News:Health News:Massage Therapy Use Holds Steady, Despite Lagging Economy 2Health News:Massage Therapy Use Holds Steady, Despite Lagging Economy 3Health News:American Lung Association Joins Health Officials to Prevent the Spread of Influenza by Urging People to Get Vaccinated 2Health News:American Lung Association Joins Health Officials to Prevent the Spread of Influenza by Urging People to Get Vaccinated 3Health News:American Lung Association Joins Health Officials to Prevent the Spread of Influenza by Urging People to Get Vaccinated 4Health News:Racial disparities decline for cancer in Missouri 2Health News:Racial disparities decline for cancer in Missouri 3Health News:2 UCSF scientists recognized for transformative research 2Health News:2 UCSF scientists recognized for transformative research 3Health News:Open cancer surgery set to become a thing of the past 2
(Date:12/15/2014)... , Dec. 15, 2014 As medical ... (Structured Product Labeling) markup language standard, content teams have ... and skills to work with the standard. Starting January ... of three webinars on the benefits and the critical ... webinars will be facilitated by Howard Shatz , ...
(Date:12/15/2014)... and BOSTON , December ... leading GPCR structure-guided drug discovery and development company, is ... in the United States relating ... these patents in the US significantly strengthens the global ... major pharmaceutical markets. The suite of patents ...
(Date:12/13/2014)... CHICAGO , Dec. 12, 2014  Radiologists ... access to images, to their referring physicians, electronic ... effectively using carefully selected technology.  ... Advanced Data Systems Corporation (ADS) at the recent ... Chicago.  The transmitting of radiology reports in this ...
Breaking Medicine Technology:Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 2Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 3Heptares Extends Global Patent Protection for GPCR-Focused Drug Discovery Platform With Grant of Core Patents in the United States 2Advanced Data Systems Presents on Interface-Free EHR Communications at RSNA's 2014 Conference: Streamlining Communication of Reports and Images to Referring Physicians 2Advanced Data Systems Presents on Interface-Free EHR Communications at RSNA's 2014 Conference: Streamlining Communication of Reports and Images to Referring Physicians 3
Visionary OFFICE™ PM offers a Windows interface featuring medical billing, appointment scheduling and patient information....
... The OmniMD Medical Billing system allows ... and accounting. It is integrated with ... capture. The system interfaces with electronic ... tracking. With a set of reports, ...
... Amylase CPNG3 single liquid stable reagent ... of single liquid stability to help ... and provide quick result turnaround time. ... Amylase CPNG3 reagent provides a long ...
... single liquid stable reagent offers the ... liquid stability to help maximize laboratory ... quick result turnaround time. The proprietary ... reagent provides a long shelf life ...
Medicine Products: