Navigation Links
New Sweetness Detectors Found in Human Taste Cells
Date:3/7/2011

MONDAY, March 7 (HealthDay News) --Taste cells apparently host more sugar detectors than previously thought, including ones formerly thought to exist only in the pancreas and intestines, new research suggests.

The finding could lead to the development of new interventions designed to help prevent overeating, the study authors say.

"Detecting the sweetness of nutritive sugars is one of the most important tasks of our taste cells," senior author Dr. Robert F. Margolskee, a molecular neurobiologist at the Monell Chemicals Senses Center in Philadephia, said in a news release. "Many of us eat too much sugar and to help limit overconsumption, we need to better understand how a sweet taste cell 'knows' something is sweet."

Margolskee and his colleagues report their observations in this week's issue of the Proceedings of the National Academy of Sciences.

Until now, investigators had focused on one particular taste cell receptor (known as T1r3+Tr3) as the main detector of all things sweet, including both natural sugars and artificial sweeteners.

This sensor, however, did not appear to account for all aspects of sweetness detection.

So, the authors harnessed high-tech molecular and cellular lab methods to explore whether or not additional sugar sensors -- those central to the digestive process that takes place in both the intestine and pancreas -- might also be present in taste cells.

The result: those same sugar sensors were thriving in taste cells. In fact, several sugar sensors found in the intestine and pancreas were fingered as being present in the same taste cells that house the well-known T1r3+T3r receptor.

For example, the newly located taste cell receptor known as SGLT1 (previously detected solely in the intestine) was found to account for the sweet taste that registers when consuming a pinch of table salt. Another newly found sensor, known as KATP and previously attributed solely to t
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. One-third of antimalarial medicines sampled in 3 African nations found to be substandard
2. Michael J. Fox Foundation Awards $1 Million to Drive Critical New Research Tools and Technologies in Parkinsons Drug Development
3. Highmark Foundation Awards $120,000 to the American Heart Association
4. Stuttering Foundation Hails New Research
5. Autism Science Foundation Offers IMFAR Grants to Autism Stakeholders
6. Alzheimers Foundation of America Applauds Social Security for Speeding Disability Benefits for Early-Onset Alzheimers Disease
7. Corbett Accel Healthcare Group Mourns Passing of Founder Frank J. Corbett
8. Reliv Foundation Donates $450,000 In Nutritional Supplements to Haitian Relief Efforts
9. Kaiser Foundation Health Plan and Hospitals Report Fourth Quarter and Fiscal Year 2009 Financial Results
10. Instaflex Announces Proceeds Agreement with Arthritis Foundation
11. AMERICAN IDOL to Benefit the UN Foundation Fund for Haiti Thursday, February 25, on FOX
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Sweetness Detectors Found in Human Taste Cells
(Date:7/25/2014)... when genes are switched on or off plays a ... regulate metabolism, UT Southwestern Medical Center researchers have found., ... treat obesity and diabetes, since the transcription factor involved ... to influence the body,s sensitivity to insulin and leptin ... body,s regulation of food intake and sugar disposal, and ...
(Date:7/25/2014)... (PRWEB) July 25, 2014 Innerspire, LLC ... joined the company as a Creative Enrollment Specialist. In ... relationship building skills as well as his accomplished design ... small business clients, and to service the creative ... Additionally, Greg will work with small business owners and ...
(Date:7/25/2014)... The American Brain Tumor Association (ABTA) ... CommYOUnity™” during its annual patient and family conference in ... brain tumor community as we – the first and ... services and funding brain tumor research – extend our ... tumor awareness and getting our materials and services into ...
(Date:7/25/2014)... July 25, 2014 There are 700,000 people ... diagnosed each day. Though when someone hears the words, “you ... are unsure of the next step and where to turn. ... figure out that next step by providing and pursuing the ... than Brian Olson, member of the ABTA’s Board of Directors ...
(Date:7/25/2014)... Progress in understanding the molecular genetics of brain ... brain tumor treatments, according to Patrick Wen, MD, professor ... for Neuro-Oncology, Dana-Farber Cancer Institute. , At the American ... in Chicago, July 25-26, Dr. Wen will moderate a ... the development of new treatments and advancing strategies to ...
Breaking Medicine News(10 mins):Health News:Manipulating key protein in the brain holds potential against obesity and diabetes 2Health News:Innerspire, LLC Continues National Expansion 2Health News:Innerspire, LLC Continues National Expansion 3Health News:Innerspire, LLC Continues National Expansion 4Health News:American Brain Tumor Association Unveils Brand Identity for Newly Launched Volunteer Network 2Health News:American Brain Tumor Association Unveils Brand Identity for Newly Launched Volunteer Network 3Health News:American Brain Tumor Association Board of Directors Member Shares Story of Brain Tumor Survivorship 2Health News:American Brain Tumor Association Board of Directors Member Shares Story of Brain Tumor Survivorship 3Health News:Immunotherapy, Targeted Molecular Therapies Among Promising New Treatments for Brain Tumors 2Health News:Immunotherapy, Targeted Molecular Therapies Among Promising New Treatments for Brain Tumors 3Health News:Immunotherapy, Targeted Molecular Therapies Among Promising New Treatments for Brain Tumors 4
... its truth when then Researchers of Arizona University did a ... D.Martinez and collegues , girls who become overweight or obese ... have a sevenfold increased risk of developing asthma .The boys ... if they are obese , the researchers say. , The ...
... research that suggests high doses of vitamin E may ... prevalent diseases in the world with many ravaging complications, ... heart disease, eye damage, kidney failure, non healing ulcers ... of the nervous system. ,Diabetes is caused by ...
... of Pfizer. The pharmaceutical giant has announced that it ... by the AIDS virus. The decision by the Pfizer comes ... a landmark case against pharmaceutical companies. In an announcement ... be given free of cost to battle HIV through a ...
... Azad Medical College, New Delhi has created history of ... from the American patent office for his technique in ... ,A few weeks ago the American patent office granted ... was able to regenerate organs like the uterus, urethra ...
... West is now sitting up and taking in the aroma ... spices are now the subjects of research by scientists at ... C. Fung and colleagues who conducted the study opine that ... can also double up as an anti bacterial agent. ...
... a little quality time with one's spouse and other partners ... pressure. In a study that used portable monitors to ... pressure was lowest when they were with their partners, regardless ... of the State University of New York, the lead study ...
Cached Medicine News:
(Date:7/24/2014)... VIEW, Calif. , July 24, 2014  IRIDEX ... it will release its second quarter 2014 financial results ... 2014. In conjunction with the release, the Company ... at 5:00 p.m. Eastern Time on ... of the quarter and other business developments. ...
(Date:7/24/2014)... 2014 Omnicell, Inc. (NASDAQ: ... supply management solutions and analytics software for healthcare ... to discuss the Company,s Second Quarter 2014 financial ... earnings conference call and webcastWhen: , July ... chairman, president and chief executive officer ...
(Date:7/24/2014)... N.J., July 24, 2014  IGI Laboratories, Inc. (NYSE MKT: ... manufacturing company, announced its financial results for the second quarter ... , Total revenues of $6.5 million in the ... same quarter in 2013 , Total revenues of $13.3 ... increase of 78% over the same period in 2013 ...
Breaking Medicine Technology:Omnicell to Release Second Quarter 2014 Earnings Results on July 31 2IGI Laboratories Announces Second Quarter 2014 Results 2IGI Laboratories Announces Second Quarter 2014 Results 3IGI Laboratories Announces Second Quarter 2014 Results 4IGI Laboratories Announces Second Quarter 2014 Results 5IGI Laboratories Announces Second Quarter 2014 Results 6IGI Laboratories Announces Second Quarter 2014 Results 7
... New results from the largest multicenter clinical trial for ... the International Society for Heart & Lung Transplantation (ISHLT) ...  Results show clinical benefit for the use of Everolimus ... 721 randomized patients at 67 medical centers spanning 5 ...
... April 14, 2011 Oxford Finance Corporation (Oxford), a ... a $2 million equipment loan with Synta Pharmaceuticals Corp. ... compounds for use in Synta,s ongoing clinical trials in ... "Synta Pharmaceuticals has a diverse drug pipeline, including ...
Cached Medicine Technology:Results From Largest Study of Anti-Rejection Therapy for Heart Transplant Patients Will be Released at ISHLT Meeting 2Results From Largest Study of Anti-Rejection Therapy for Heart Transplant Patients Will be Released at ISHLT Meeting 3Results From Largest Study of Anti-Rejection Therapy for Heart Transplant Patients Will be Released at ISHLT Meeting 4Oxford Finance Corporation Provides a $2 Million Equipment Facility to Synta Pharmaceuticals Corp. 2