The studies reviewed by the panel looked at aspartame's potential effect on behavior, reproductive health, neurological functions, and cancer and tumor development. They covered individuals with Parkinson's disease and diabetes; those suffering from allergies, depression and seizures; and various categories of children, including those with hyperactivity or claiming to be sensitive to sugar.
"The suggestions of adverse effects from aspartame consumption have absolutely no credible scientific basis," said William J. Waddell, MD, Professor and Chair, Emeritus, Toxicology, at the University of Louisville School of Medicine, who chaired the panel. "It is safe for all population groups."
The panel also considered recent highly publicized studies by the Italian Ramazzini group that purported to show a link between aspartame and cancer in rats. "Multiple expert evaluations, as well as our work, identified numerous flaws in the Italian studies," said Magnuson. "After careful review, our panel remains completely confident in aspartame safety."
The review panel spent 11 months looking at past research on aspartame, which entered the food supply in 1981 and is used in more than 6,000 food products worldwide, including most diet soft drinks and many sugar-free chewing gums.
The safety review was structured in a unique manner. Dr. Waddell, on
behalf of the Burdock Group, selected members to achieve representation of
the complete spectrum of toxicological expertise relevant to aspartame. The
identity of the sponsor, Ajinomoto, was unknown to the chair and expert
panel
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