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New Study Uses Adult Stem Cells in Effort to Save Limbs of Patients with Peripheral Arterial Disease
Date:2/11/2010

COLUMBUS, Ohio, Feb. 11 /PRNewswire/ -- Grant Medical Center recently completed the nation's first published study of a new procedure that may give hope to millions of patients facing lower limb amputations from peripheral arterial disease (PAD). PAD is a painful circulatory problem in the legs that affects 10 million Americans. If left untreated, it can lead to serious complications such as stroke, amputation and death.

The December issue of The Journal of Vascular Surgery has published the results of a clinical trial at Grant documenting the outcomes of nine patients who received a groundbreaking transplant of adult stem cells. The study was designed to see if the stem cells would cause new blood vessels to grow bypassing severely narrowed or clogged arteries.

Six of the patients avoided major amputation through restored blood flow that eliminated their constant pain and healed their ulcerations. "We were pleasantly surprised by our results," said vascular and endovascular surgeon Randall W. Franz, MD, medical director of the Grant Vascular and Vein Center. "This is cutting-edge technology that could benefit millions of Americans with PAD."

"A total of 16 patients have now received the procedure with 13 patients avoiding major amputation," said Dr. Franz.  

Dr. Franz co-authored the study with vascular surgeon Kaushal Shah, MD, and chief perfusionist Thomas Hankins, CCP. "This technique sheds new light on stem cell treatment and has the potential to become the gold-standard therapy for PAD," Hankins said.

During the procedure, surgeons extracted specialized stem cells from the patient's hip, separated them by centrifuge spinning and injected them into the arteries and muscles at the site of the blockage. "We actual
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SOURCE Grant Medical Center
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