Navigation Links
New Study Links Air Pollution to Alzheimer’s Disease -- Says Cure Alzheimer's Fund
Date:4/15/2013

Boston, Massachusetts (PRWEB) April 15, 2013

High levels of exposure to air pollution may increase the risk of Alzheimer’s disease, according to a new study completed with a grant from the Cure Alzheimer’s Fund.

The study, led by Cure Alzheimer’s Research Consortium member Sam Gandy, M.D., Ph.D., of the Icahn School of Medicine at Mount Sinai, examined how elements in air pollution such as nickel nanoparticles affect the levels of certain peptides in the brain that are found to be at heightened levels in patients suffering from Alzheimer’s Disease.

“We don’t yet completely understand why the peptides accumulate, but we do know the genes responding to the peptides play an important role in developing Alzheimer’s,” said Gandy.

To test the correlation, mice were examined 24 hours after being exposed to air pollution where they showed a 72-129 percent increase in levels of the peptides.

“We were startled when three hours of air pollution exposure for the mice showed such a rapid and dramatic elevation,” said Gandy.

While the study links air pollution to Alzheimer’s, Gandy emphasized that more research is needed to better understand the role of genetics saying, “There is probably some interaction between genetic susceptibility to air pollution that mitigates the response to the exposure.”

Additionally, the study emphasized the need to better understand air pollution’s effects on humans in a natural setting.

“We suspect that humans will have an even more dramatic reaction to air pollution than mice because the human molecule is far stickier, making it highly prone to clumping and accumulation,” said Gandy. This could mean an even stronger link between air pollution and Alzheimer’s than is reflected in the study’s findings.

Interest in linking air pollution exposure to Alzheimer’s disease started when studies showed young people living in highly polluted cities to have Alzheimer Disease pathology, and because of existing evidence linking air pollution to insulin resistance and Type 2 Diabetes.

“We wanted to see if we could better explain why so many people were showing signs of Alzheimer’s at such a young age,” Gandy said. “The results of this study clearly show an urgent need to better understand this link.”

In just seven years, with just $20 million spent, Cure Alzheimer’s Fund has an unparalleled track record. Its Alzheimer’s Genome Project (AGP) TM was the largest single disease scan of all time and was considered one of the “Top 10 Medical Breakthroughs in the world in 2008” by Time and CNN. Its funded research work has also been noted by The Wall Street Journal, NPR and the White House.

Read the published paper here.

Read a recent publication from the Archives/Annals of Internal Medicine linking air pollution to cognition here.

Read the full story at http://www.prweb.com/releases/2013/4/prweb10629377.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. Study Questions Value of PSA Test for Older Men
2. Doctors Insight Into Patients Lives May Boost Care, Study Finds
3. Drug could improve working memory of people with autism, study finds
4. Freezing Treatment May Help Destroy Lung Tumors: Study
5. Age of Autism Diagnosis May Depend on Symptoms: Study
6. Laser Liposuction May Zap Fat Without Skin Sag: Study
7. In sex, happiness hinges on keeping up with the Joneses, CU-Boulder study finds
8. Vitamin D may reduce risk of uterine fibroids, according to NIH study
9. Groundbreaking study to transform service users involvement in mental health care
10. Zocor Side Effects Update: Bernstein Liebhard LLP Comments on New Study Linking Kidney Problems to High Doses of Zocor, Other Statins
11. Mirena Lawsuits Move Forward, as Bernstein Liebhard LLP Comments on New Mirena IUD Side Effects Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica Scruggs ... for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs surgery, ... Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, MD, ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/24/2016)... ... , ... June 19, 2016 is World Sickle Cell Observance Day. In an ... of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a ... Cell Disease (SCD) is a disorder of the red blood cells, which can cause ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San ... Society and the Road To Recovery® program to drive cancer patients to and from ... adults to ensure the highest quality of life and ongoing independence. Getting to ...
(Date:6/24/2016)... Vegas, Nevada (PRWEB) , ... June 24, 2016 ... ... Las Vegas client, The Grove Investment Group (TGIG), has initiated cultivation and processing ... Grove, in Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)...   Pulmatrix, Inc ., (NASDAQ: PULM ... announced today that it was added to the Russell ... comprehensive set of U.S. and global equity indexes on ... milestone for Pulmatrix," said Chief Executive Officer Robert ... progress in developing drugs for crucial unmet medical needs, ...
(Date:6/23/2016)... BEVERLY HILLS, Calif. , June 23, 2016 ... faced the many challenges of the current process. Many of ... option because of the technical difficulties and high laboratory costs ... would have to offer it at such a high cost ... to afford it. Dr. Parsa Zadeh , ...
(Date:6/23/2016)... 2016 Capricor Therapeutics, Inc. ... biotechnology company focused on the discovery, development and ... enrollment in its ongoing randomized HOPE-Duchenne clinical trial ... of its 24-patient target. Capricor expects the trial ... of 2016, and to report top line data ...
Breaking Medicine Technology: