Navigation Links
New Study Finds Cholesterol-Related Gene Associated with Mild Cognitive Impairment, a Precursor of Alzheimer's Disease
Date:3/9/2010

Scientists find that a genetic mutation causing a common hereditary form of high blood cholesterol dramatically increase the risk of MCI.

(PRWEB) March 9, 2010 -- A new study from scientists in the United States and Spain has found that a mutation in a gene causing a common hereditary form of high blood cholesterol is associated with “mild cognitive impairment” (MCI), a precursor stage of Alzheimer’s disease. Worldwide, Alzheimer’s disease is the most common form of dementia affecting elderly individuals. It is usually preceded by a period characterized mainly by memory deficits known as MCI. The study will be published in the March issue of the American Journal of Medicine.

Leading the study were Dr. Miguel Pappolla and Dr. Kumar Sambamurti from the Medical University of South Carolina in Charleston and Dr. Daniel Zambon from the University of Barcelona in Spain. Their groups of scientists examined memory and other brain functions in a group of patients with familial hypercholesterolemia, a hereditary condition caused by a mutation in the low density lipoprotein receptor, a protein involved in the transport of cholesterol into cells. Patients with familial hypercholesterolemia showed a very high incidence of MCI (21 percent) when compared with age-matched individuals without the disease (2.9 percent).

For almost a decade, it has been suspected that individuals with high blood cholesterol during mid-life may carry a higher risk of developing Alzheimer’s disease. However, the evidence for this association was controversial and the mechanisms unknown. Although non-hereditary forms of Alzheimer’s disease do not show this type of mutation, the recent finding, says Pappolla, is of paramount importance as it points to a defect on the cholesterol transport systems underlying the risk of developing MCI.

For more information about this study and its findings, contact Miguel Pappolla, MD, PhD.

Contact:
Miguel Pappolla, MD, PhD.
228-219-7246
DrP(at)stmichaelclinics(dot)com
www.SMPSclinic.com

###

Read the full story at http://www.prweb.com/releases/mild-cognitive-impairment/cholesterol/prweb3685634.htm.


'/>"/>
Source: PRWeb
Copyright©2010 Vocus, Inc.
All rights reserved  

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Study Finds Cholesterol-Related Gene Associated with Mild Cognitive Impairment, a Precursor of Alzheimer's Disease
(Date:4/29/2016)... ... April 29, 2016 , ... In an article ... shares her enthusiasm for Botox and lip injections, which she underwent in order to ... Coachella Valley Music and Arts Festival. The article explains that Ms. Mirmelli’s situation is ...
(Date:4/29/2016)... ... , ... Our bodies are bombarded daily by environmental and lifestyle factors that ... is to adopt a more healthful diet, but too many people think that food ... Nutritionist and the creator of the Newport Beach Cleanse and 14-Day Eating Plan, disagrees ...
(Date:4/29/2016)... ... April 29, 2016 , ... The White House announced ... loans, more information about their loan terms and accounts, and more protections for ... including federal and private loans, has reached $1.3 trillion, with 43 million Americans ...
(Date:4/29/2016)... ... ... Spine Team Texas, a comprehensive spine physician group specializing in the treatment ... been invited to be a featured speaker at the Texas Society of the American ... 2016. , Dr. R. Scott McPherson, a physical medicine and rehabilitation specialist, will ...
(Date:4/29/2016)... , ... April 29, 2016 , ... ... Canadian Celiac Association (CCA), is pleased to announce the launch of the ... nutritional articles, recipes, and more. The purpose of the GFCP Scoop ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... April 27, 2016 Tie-up with ... initiative to save newborns   Fortis ... & newborns in collaboration with Breast Milk Foundation (BMF), a ... Pasteurized Human Milk Bank, ,Amaara, in Delhi-NCR today. This non-profit ... source for infants and should be available to babies deprived ...
(Date:4/27/2016)... YORK , April 27, 2016 ... OASM ), a developer of a new generation ... announced positive overall survival results for Paclical/Apealea in ... of 789 patients with epithelial ovarian cancer. These ... groups: Paclical/Apealea in combination with carboplatin versus Taxol ...
(Date:4/26/2016)... Diplomat Pharmacy, Inc. (NYSE: DPLO) is pleased ... Pharm D., to Vice President of Education and Quality. ... will continue to lead and oversee Diplomat University, an ... and training to Diplomat employees and external professionals on ... also houses the quality assurance department, which focuses on ...
Breaking Medicine Technology: