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New Study Demonstrates Novel Use of Metabolic Imaging to Locate Sperm in Infertile Men -- Non-Invasive Imaging Procedure May Replace Invasive Techniques such as Testicula
Date:2/4/2010

Men with no sperm in their ejaculate may no longer need invasive procedures to determine if they have sperm in their testes according to a new study published in Human Reproduction.

San Francisco, CA (Vocus) February 4, 2010 -- Men with no sperm in their ejaculate –a condition known as azoospermia —may no longer need invasive procedures to determine if they have sperm in their testes according to a new study published in Human Reproduction.

Instead, the study found that MR Spectroscopy—a simple metabolic scan that combines the use of 1H Spectroscopy with magnetic resonance imaging (MRI)—can be used to determine the likelihood of finding sperm in men with non-obstructive azoospermia (NOA).

The study’s lead author is Paul Turek, MD, former professor and endowed chair at the University of California San Francisco and founder of The Turek Clinic.

“Some men with azoospermia may still have small amounts of sperm in the testicle, but determining which of these men has retrievable sperm is challenging. This is a novel and exciting application of metabolic scanning that shows great potential to eliminate invasive biopsies and gives new hope to infertile men who wish to father children,” said Dr. Turek, a men’s reproductive health expert.

Traditional methods for evaluating if sperm exist, including testicular biopsy and microdissection are highly invasive and have only a 60 percent to 65 percent success rate. FNA Sperm Mapping, pioneered by Dr. Turek, is far less invasive, but still involves the use of fine needle aspiration to obtain tissue samples from the testes.

In contrast, MR Spectroscopy, or magnetic resonance spectroscopic imaging, is a non-invasive scan that measures metabolic activity in the testis. The study shows that the scan is as accurate as a more invasive testis biopsy in reading several abnormal pa
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