Navigation Links
New Stem Cell Growth Strategy Could Yield Better Way to Treat Brain Lesions
Date:5/16/2013

Durham, NC (PRWEB) May 16, 2013

Researchers have found a new way to increase the survival of stem cells injected into the brain. The discovery might one day prove useful in developing new treatments for neurological disorders — especially brain lesions, which among other things can provoke seizures and indicate multiple sclerosis or certain forms of cancer.

The study was performed by Sushma Chaubey, Ph.D., and John H. Wolfe, V.M.D., Ph.D., of the Children's Hospital of Philadelphia’s Research Institute and the University of Pennsylvania School of Veterinary Medicine. It appears in the current issue of STEM CELLS Translational Medicine.

Many medical experts have long believed that neural stem cells (NSCs) have great potential for treating neurological diseases. However, the problem is that just a small number of NSCs can be transplanted into the brain, yielding relatively low levels of new cell growth and, thus, a limited effect. “We wanted to investigate whether using a specific population of neural cells would help increase the number of mature brain cells that the stem cell graft yields,” Dr. Wolfe explained.

The team began by harvesting NSCs from the brains of baby mice and used a process known as fluorescence activated cell sorting to identify cells with markers for CD15, a type of carbohydrate found on a cell’s surface that plays an important role in cell migration, adhesion and in the growth factor signaling involved in cell maintenance and differentiation.

Cells sorting allowed the scientists to achieve a population of cells in which 98 percent were CD15-positive. This process resulted in six times more CD15-positive cells than when cell sorting is not used. These cells were then differentiated in the lab into neurons, astrocytes and oligodendrocytes, which are types of cells found in the central nervous system (the brain and spinal cord). The team next tested both sorted and non-sorte
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Demand for Dental Care Drives Growth in the Dental Orthodontic Supplies Market, According to New Report by Global Industry Analysts, Inc.
2. Global Critical Care Market Will Reach $3.2 Billion in 2019 - Growth from Factor Concentrates, New Indications and Increasing Demand for Albumin in Asia-Pacific
3. Provillus Breakthrough Hair Regrowth Formula Works in a More Gender-Specific Manner
4. Bacteria in Babys Belly May Influence Growth, Study Says
5. Medical Device Companies Eke Out Growth In Tough Market, Finds Latest Kalorama Report
6. New SMB Cloud Market in the APAC Region 2012-2016 - SMB Cloud Industry Share, Size, Trends, Analysis, Growth And Forecast Report To 2016
7. SmartSearch Marketing, a B2B Search Marketing Agency, Adds Content Strategy Manager to Serve Rapid Client Growth
8. Time to tumor growth helps predict survival benefit of Bevacizumab for patients with metastatic colorectal cancer
9. Active Pharmaceutical Ingredients (API) Market in Europe Will Reach $38,255.67 Million By 2017- Pricing and Reimbursement Initiatives Supporting Generic Drug Growth
10. It Works! Global Named Top Company for Growth and Momentum
11. New HGH.com Web Site - Purchasing Human Growth Hormone and Bodybuilding Supplements Just Got Easier
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... York, New York (PRWEB) September 15, 2014 ... C.R. Bard, Inc. continue to move forward in the ... Southern District of West Virginia, Bernstein Liebhard LLP reports. ... issued a Final Order on September 10th that provides ... The Order notes that none of the affected plaintiffs ...
(Date:9/15/2014)... studies, approximately one out of every 40 individuals in the ... spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles ... Missouri have made a recent breakthrough with the development of ... models of the disease. In April, a patent was filed ... our lab is using to fight SMA is to ,repress ...
(Date:9/15/2014)... 2014 This year, Avenidas Village ... 2007. To mark the special occasion, Avenidas Village would ... village and helping it to get started seven years ... fun community for seniors. Members of Avenidas Village maintain ... in their own homes. They are able to have ...
(Date:9/15/2014)... Sept. 15, 2014 (HealthDay News) -- Births of multiple ... and death than singleton births, researchers report. The ... in vitro fertilization (IVF) could ease some of that ... have increased in tandem with births to older mothers ... from the University of New South Wales, Australia. ...
(Date:9/15/2014)... 2014 Providing additional expertise to ... LLP (“the Firm”) is proud to welcome ... with the Firm’s Litigation Support Services ... experience, Wolf will assist clients in litigation support, ... advisory matters. He will also provide guidance in ...
Breaking Medicine News(10 mins):Health News:C.R. Bard Transvaginal Mesh Lawsuits Move Forward, With Issuance of New Order in Federal Multidistrict Litigation, Bernstein Liebhard LLP Reports 2Health News:C.R. Bard Transvaginal Mesh Lawsuits Move Forward, With Issuance of New Order in Federal Multidistrict Litigation, Bernstein Liebhard LLP Reports 3Health News:Researcher develops and proves effectiveness of new drug for spinal muscular atrophy 2Health News:Avenidas Village Celebrates Anniversary 2Health News:Study Ties Multiple Births to Higher Costs, Complications 2Health News:Study Ties Multiple Births to Higher Costs, Complications 3Health News:Cherry Bekaert Expands its Litigation Support Services Team Capabilities with the Addition of Steven Wolf 2Health News:Cherry Bekaert Expands its Litigation Support Services Team Capabilities with the Addition of Steven Wolf 3
... Over time, they boost risk for ulcers and even amputation, ... Something as simple as wearing the wrong size of shoes ... could lead to amputation, Scottish researchers say. , The study, ... diabetes patients, ages 24 to 89, who had their feet ...
... The use of a pedometer and a Web site that ... people with diabetes who participated in a recent walking study ... and VA Ann Arbor Healthcare System. The study also suggests ... others. , All participants in the study wore pedometers and ...
... most harmful strains of human papillomavirus is under study ... called nine-valent, is being compared with Gardasil, a quadrivalent ... two most deadly HPV types. , Were testing Gardasil ... Dr. Daron Ferris, family medicine physician and director of ...
... Researchers here have shown that in cell cultures, ... signals that stimulate certain tumor cells to grow and ... a way of slowing the progression and spread of ... have a better chance to work. , The ...
... Family Caregiver,s Month; Announces Availability ... More than 34 Million Caregivers, PALO ALTO, Calif., Nov. ... proud to support the more than 34 million,Americans caring for ... availability of its website. Designed to give caregivers the ...
... BAY, Wis., Nov. 19 Shopko announced today plans,to ... the fall of 2008. The,stores will be located in ... the continuation of an exciting growth,phase for Shopko," said ... Earlier this year Shopko broke ground on the first ...
Cached Medicine News:Health News:Ill-Fitting Shoes a Danger to Diabetics 2Health News:Pedometers motivate people with diabetes to walk more 2Health News:Pedometers motivate people with diabetes to walk more 3Health News:New HPV vaccine under study 2Health News:Stress hormone may hasten the progression of certain blood cancers 2Health News:Stress hormone may hasten the progression of certain blood cancers 3Health News:Resource to Help Care for Aging Parents Now Available Nationwide 2Health News:Resource to Help Care for Aging Parents Now Available Nationwide 3Health News:Shopko Announces Plans for Two New Stores 2
(Date:9/15/2014)... Sept. 15, 2014 PDL BioPharma, Inc. (PDL) (NASDAQ: ... paid the September 12, 2014, regular quarterly dividend payment of ... PDL as of September 5, 2014, the record date. ... manages a portfolio of patents and royalty assets, consisting ... and license agreements with various biotechnology and pharmaceutical companies. ...
(Date:9/15/2014)... Sept. 15, 2014 Research and Markets ... Drug Transfer Systems to 2020" report to their ... hazardous to humans has been receiving increasing amounts of ... substances become more clearly understood. For caregivers and their ... of attempts to mitigate exposure to cytotoxic drugs is ...
(Date:9/15/2014)... -- Research and Markets has announced the addition ... Tests, 9th Edition" report to their offering. ... testing market and all of its segments, providing customers with ... For Business Planning. This is the ninth edition ... 2013 and early 2014. New entrants, new technologies have entered ...
Breaking Medicine Technology:PDL BioPharma Completes Regular Quarterly Dividend Payment 2Closed Drug Transfer Systems to 2020 2Closed Drug Transfer Systems to 2020 3The Worldwide Market for In Vitro Diagnostic Tests, 9th Edition 2The Worldwide Market for In Vitro Diagnostic Tests, 9th Edition 3
... 17, 2011 Attorneys representing a group of U.S. citizens ... the drug thalidomide have filed a lawsuit in federal court ... show the drug was widely distributed in the United States. ... to respond to a number of Freedom of Information Act ...
... WASHINGTON, Nov. 17, 2011 The proliferation of brand ... generics to more expensive brands, will increase costs by ... employers, unions, and state employee plans, according to new ... Care Management Association (PCMA).   The use of these ...
Cached Medicine Technology:Hagens Berman: Patients Seek to Force FDA to Release Records Showing US Distribution of Thalidomide 2Hagens Berman: Patients Seek to Force FDA to Release Records Showing US Distribution of Thalidomide 3Brand Drug 'Copay Coupons' Undermine Generics, Raise Health Costs by $617 Million in Wisconsin 2
... is a threaded titanium anchor, ... procedures. The anchor features wide ... to optimize bone purchase, as ... to prevent suture binding. Fastin ...
The GII titanium anchor is the "Gold Standard" for soft tissue reattachment to bone. The GII's small size, high pull-out strength and wide range of clinical applications make it the anchor of choice ...
... 'proximal protection' -- providing complete protection from ... vessels with side branches. , ,Proxis ... does not require the attachment or exchange ... debris. ,Proxis is compatible with all ...
... System is the Fischer answer to cost ... specialist. The EP-X system is a highly ... dedicated EP lab system. Ease of access ... Pulsed Progressive Fluoroscopy (PPF) are but a ...
Medicine Products: