Navigation Links
New Statistical Model Could Cut Needless Breast Biopsies
Date:12/5/2008

But further study needed before method can become standard, researchers say

FRIDAY, Dec. 5 (HealthDay News) -- A new statistical model may help radiologists better determine whether a breast lesion detected by MRI is malignant or benign, something that could help prevent unnecessary biopsies, say U.S. researchers.

They reviewed almost 2,600 breast MRI exams conducted over four years at the Seattle Cancer Care Alliance and identified three important categories of patient and lesion characteristics that, when used in combination, could predict the likelihood of cancer. The three are: the reason a woman is having a breast MRI; the size of the lesion; and the lesion enhancement pattern from the MRI contrast dye.

Lesions most likely to be malignant were: in women undergoing MRI to look for additional malignancy after new breast cancer diagnosis; lesions larger than one centimeter; and those whose enhancement quickly faded (called washout).

Lesions most likely to be benign were: in women being screened because they're considered to be at high risk for cancer; small lesions; and those with increased enhancement over time.

"If the lesions had those three characteristics, the likelihood of malignancy was 1 percent. This is so close to zero that rather than doing a biopsy, we could instead follow the patient by doing another MRI in a few months, or we may not need to do any additional testing," Dr. Wendy DeMartini, an assistant professor in the University of Washington School of Medicine, said in a Fred Hutchinson Cancer Research Center news release.

Futher study is required before this statistical model can be validated for use as standard practice.

"This is a preliminary model. Future work will look at additional patient and lesion features, and in the longer term, we need to examine lesions from multiple practice sites," DeMartini said. "Our goal is to identify a group of lesions that we currently recommend for additional tests where the likelihood of cancer is so low that we can safely avoid additional testing."

The research was presented Sunday at the Radiological Society of North America annual meeting, in Chicago.

More information

The American Cancer Society has more about breast biopsy.



-- Robert Preidt



SOURCE: Fred Hutchinson Cancer Research Center, news release, Nov. 30, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New statistical model could help reduce breast-lesion biopsies
2. Academy of General Dentistry Releases Updated Employment Statistical Map
3. Statistical Bowl - How the 07 Patriots and the 72 Dolphins Match Up
4. In Landmark Phase III Head-to-Head Study, Prasugrel Statistically Superior to Clopidogrel in Reducing Risk of Heart Attack
5. Once-Weekly Exenatide Showed Statistical Superiority in Glucose Control Compared to BYETTA in Head-to-Head Study
6. Medicare Prescription Drug Benefit, Nonprofit Hospitals, Ambulatory Surgery Centers, Statistical Methods, and Pay-For-Performance Highlighted In the Latest INQUIRY Journal
7. Corporate Modelling Partners Start Selling BPM in Cloud Service
8. Americans United for Life Urges State Legislatures to Oppose Federal Power Grab: Provides Model Resolution Denouncing Freedom of Choice Act (FOCA)
9. Sealing off portion of intestinal lining treats obesity, resolves diabetes in animal model
10. California Drug Rehab Facility Completes Comprehensive Remodeling Project
11. New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Statistical Model Could Cut Needless Breast Biopsies 
(Date:12/6/2016)... ... December 06, 2016 , ... It can be argued that people these days ... members as they do for their human friends and family. As pets have ... highest quality and most innovative pet products has also increased. , For ...
(Date:12/6/2016)... ... December 06, 2016 , ... The Behavioral Health Center ... recognizing the organization as a top behavioral service provider in the country. The ... quality, staff satisfaction and qualifications, and consumer satisfaction. These areas are measured via ...
(Date:12/6/2016)... ... December 06, 2016 , ... Gateway Analytical, one of ... particle counting and sizing services for USP 788 and 789 particulate standards compliance. ... as a response to the needs of pharmaceutical and medical device manufacturers, who ...
(Date:12/6/2016)... ... December 06, 2016 , ... ... the much-anticipated HydroFX for Water®. This first-of-its-kind water-soluble powder supplement has a ... world’s most powerful antioxidants, molecular hydrogen, HydroFX for Water transforms every day ...
(Date:12/6/2016)... Vancouver, B.C., Canada (PRWEB) , ... December 06, ... ... Consultants (STC) announce the availability of the newly updated International Audit Protocol Consortium ... world use IAPC EHS audit protocols to understand the scope of their EHS ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... N.J. , Dec. 5, 2016  Daiichi ... preliminary safety and efficacy data from a phase ... MDM2 inhibitor, suggesting that DS-3032 may be a ... myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS). ... the phase 1 study of DS-3032 were presented in ...
(Date:12/5/2016)... -- BD (Becton, Dickinson and Company) (NYSE: BDX ... an enhanced technology platform designed with the ability to ... Pyxis™ and Alaris™ systems, at this year,s American ... being held in Las Vegas ... that approximately 68 percent of medication errors occur during ...
(Date:12/5/2016)... , Dec. 5, 2016 Eisai Inc. ... at the 2016 Annual Meeting of the American Epilepsy ... CIII, is indicated as an adjunctive therapy for the ... secondarily generalized seizures and primary generalized tonic-clonic seizures (PGTC) ... age and older. Please see Important Safety Information for ...
Breaking Medicine Technology: