Navigation Links
New Stanford method enables sequencing of fetal genomes using only maternal blood sample
Date:7/4/2012

STANFORD, Calif. -- Researchers at the Stanford University School of Medicine have for the first time sequenced the genome of an unborn baby using only a blood sample from the mother.

The findings from the new approach, to be published July 4 in Nature, are related to research that was reported a month ago from the University of Washington. That research used a technique previously developed at Stanford to sequence a fetal genome using a blood sample from the mother, plus DNA samples from both the mother and father.

The whole genome sequencing in the new Stanford study, however, did not require DNA from the father a significant advantage when a child's true paternity may not be known (a situation estimated to affect as many as one in 10 births in this country) or the father may be unavailable or unwilling to provide a sample. The technique brings fetal genetic testing one step closer to routine clinical use.

"We're interested in identifying conditions that can be treated before birth, or immediately after," said Stephen Quake, PhD, the Lee Otterson Professor in the School of Engineering and professor of bioengineering and of applied physics. "Without such diagnoses, newborns with treatable metabolic or immune system disorders suffer until their symptoms become noticeable and the causes determined." Quake is the senior author of the research. Former graduate student H. Christina Fan, PhD, now a senior scientist at ImmuMetrix, and current graduate student Wei Gu are co-first authors of the article.

As the cost of such technology continues to drop, it will become increasingly common to diagnose genetic diseases within the first trimester of pregnancy, the researchers believe. In fact, they showed that sequencing just the exome, the coding portion of the genome, can provide clinically relevant information.

In the new study, the researchers were able to use the whole-genome and exome sequences they obtained to det
'/>"/>

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Stanford Woods Institute for the Environment announces 2012 Environmental Venture Project awards
2. Stanford study shows opiates side effects rooted in patients genetics
3. Proposed testosterone testing of some female olympians challenged by Stanford scientists
4. Stanford researchers discover the African cichlids noisy courtship ritual
5. Antioxidant shows promise as treatment for certain features of autism, Stanford study finds
6. New type of retinal prosthesis could better restore sight to blind, Stanford study says
7. Invasive heart test being dramatically overused, Stanford study shows
8. Electronic data methods research seeks to build a learning health care system
9. New delivery method improves efficacy of 2 common Parkinsons disease medications
10. Quick-Reversal Method May Be at Hand for New Blood Thinner
11. Safer Grilling Methods Might Cut Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... August 27, 2014 Taking its popular obstacle ... Steele Creek YMCA will host its largest crowd at ... Saturday, September 13 at YMCA Camp Thunderbird . ... divisions: adult, youth and teams. Within each division, runners ... their physical limit - for a worthy cause. All ...
(Date:8/27/2014)... 27, 2014 Reviewing the prices that ... be easier for the public when using the Quotes ... promoted in all 50 states in the U.S. are ... different insurers that are generating the rates information from ... adults to use the programmed system without charge. Because ...
(Date:8/27/2014)... Shawna's new book, released in ebook ... Digging, which a brand-new technique she created. Seed digging ... to bring permanent healing quickly. , According to Burns, ... disorders cured on a daily basis. It teaches people ... find incredible inner peace with only a few simple ...
(Date:8/27/2014)... The New York Mobility Club (sponsored ... events about “ Sexuality & Intimacy ” for people ... and entertaining discussions are for mature audiences only. September ... Avenue, Mamaroneck, NY) and October 7 from 6-8 pm ... , The New York Mobility Club is a local ...
(Date:8/27/2014)... 2014 Top 10 Best SEO Hosting, a ... hosting suppliers and announced iPage, Bluehost and GoDaddy are the ... Australia and Europe to buy useful hosting (including VPS and ... suppliers, iPage has been serving hosting small business ... has grown into a leader in the hosting industry for ...
Breaking Medicine News(10 mins):Health News:C2 Survival Racers Go to Extremes to Provide Kids with YMCA Programs 2Health News:Home Insurance Prices for All 50 States Now Supplied at Consumer Insurance Portal Online 2Health News:Shawna Burns, Counselor, Releases Debut Book, "Seed Digging," to Improve Lives of Children and Adults with Addictions and Mental Health Disorders 2Health News:Bussani Mobility Sponsors New York Mobility Club Meetings September 9 & October 7 for People with Disabilities, Sexuality & Intimacy Discussed by Advocate Liz Treston 2Health News:Well-known SEO Hosts Review Site Top10BestSEOHosting.com Recommends iPage, Bluehost and GoDaddy To Webmasters 2
... BIRMINGHAM, Ala., Sept. 8 BioCryst Pharmaceuticals, Inc. (Nasdaq: ... summaries at two upcoming investor conferences. , , ... is scheduled to present a corporate summary at the Rodman & ... 2:25 p.m. Eastern Time. The conference will be held September 9-11, ...
... ... Use in Epocrates Survey , ... San Mateo, CA (PRWEB) September 8, 2009 -- Epocrates, Inc., a leading provider ... role of technology use in hospitals and clinics across the nation. , , ,The majority ...
... , , , ... on its recent analysis of the dairy animal nutrition market, ... business of Church & Dwight Company Incorporated, with the 2009 ... the Year Award. It acknowledges the company,s excellence in developing ...
... , , LONDON, Sept. ... Ingredients Excellence in Financial & Risk Management Award is presented ... the first and only EU-and FDA-approved omega-3 derived prescription drug. ... the USA, the product is a prescribed adjunct to diet ...
... ... in using electronic cigarette, the private research group has recently completed survey of 10,000 ... ... is a battery-powered device that provides inhaled doses of nicotine by delivering a vaporized ...
... ... testimonial for ColorAlchemy by licensed Marriage and Family Therapist and Clinical Hypnotherapist David Swindoll now ... ... Therapist and Clinical Hypnotherapist for over thirty years. He has found the use of ColorAlchemy ...
Cached Medicine News:Health News:BioCryst Executives to Present at Two Investor Conferences 2Health News:Nurses Facing National Shortage Turn to Mobile Technology to Support Patient Care 2Health News:Frost & Sullivan Cites Arm & Hammer for Excellence in the Dairy Animal Nutrition and Management Market 2Health News:Frost & Sullivan Cites Arm & Hammer for Excellence in the Dairy Animal Nutrition and Management Market 3Health News:Frost & Sullivan Cites Arm & Hammer for Excellence in the Dairy Animal Nutrition and Management Market 4Health News:Frost & Sullivan Global Heart Health Ingredients Excellence in Financial & Risk Management Award Conferred on Pronova BioPharma 2Health News:Frost & Sullivan Global Heart Health Ingredients Excellence in Financial & Risk Management Award Conferred on Pronova BioPharma 3Health News:Frost & Sullivan Global Heart Health Ingredients Excellence in Financial & Risk Management Award Conferred on Pronova BioPharma 4Health News:Frost & Sullivan Global Heart Health Ingredients Excellence in Financial & Risk Management Award Conferred on Pronova BioPharma 5Health News:Electronic Cigarette Known as ecig Helps You Quit Smoking 2Health News:Electronic Cigarette Known as ecig Helps You Quit Smoking 3Health News:Licensed Marriage and Family Therapist and Clinical Hypnotherapist Provides Powerful Video Testimony for ColorAlchemy and Color Therapy 2Health News:Licensed Marriage and Family Therapist and Clinical Hypnotherapist Provides Powerful Video Testimony for ColorAlchemy and Color Therapy 3
(Date:8/27/2014)... , Aug. 27, 2014  Hill-Rom Holdings, Inc. ... to a management presentation at the Morgan Stanley Global ... EDT. You are invited to listen to ... http://ir.hill-rom.com/events.cfm or access it directly at http://cc.talkpoint.com/morg007/090814a_ac/?entity=26_7CLOGQP ... available one hour after conclusion of the live event ...
(Date:8/27/2014)... 2014 Sihuan Pharmaceutical Holdings Group Ltd. ... leading pharmaceutical company with the largest cardio-cerebral vascular ... prescription drug market, today announced the unaudited ... (collectively the "Group") for the six months ended ... HighlightsFor the Six months ended 30 JuneKey Income ...
(Date:8/27/2014)... , Aug. 27, 2014  CVS Caremark (NYSE: ... into a new clinical affiliation with MedStar Health, a ... Maryland and the Washington, ... high-quality, affordable health care services for patients. Through this ... access to clinical support, medication counseling, chronic disease monitoring ...
Breaking Medicine Technology:Sihuan Pharmaceutical Announces 2014 Interim Results 2Sihuan Pharmaceutical Announces 2014 Interim Results 3Sihuan Pharmaceutical Announces 2014 Interim Results 4Sihuan Pharmaceutical Announces 2014 Interim Results 5Sihuan Pharmaceutical Announces 2014 Interim Results 6Sihuan Pharmaceutical Announces 2014 Interim Results 7CVS Caremark Announces New Clinical Affiliation with MedStar Health 2CVS Caremark Announces New Clinical Affiliation with MedStar Health 3
... 2010 Curemark LLC , a drug research and ... today that it has been awarded a grant by the ... Program to advance the development of its lead product CM-AT ... at 18 sites around the US. The QTDP ...
... VALLEY, Calif., Nov. 2, 2010 Spectros Corporation ... with the T-Stat VLS Tissue Oximeter at the ... newly released data was presented during poster sessions ... Circulation: Pharmacology/Physiology", held at the American Society of ...
Cached Medicine Technology:Curemark Awarded Qualifying Therapeutic Discovery Project (QTDP) Grant 2Spectros Presents New Clinical Studies Using T-Stat VLS Tissue Oximeter at Anesthesiology 2010 2
... for urinary albumin that allows for early ... CLIA Waived test has a sensitivity of ... gives accurate results in only 3 minutes ... hours. Since early detection is one key ...
... Drug Screen Tests are available in 14 ... (Ecstasy). Designed using Microgenics Antibody Technology, the ... point of care immunoassay targeted to detect ... MDA and MDEA but no cross-reactivity to ...
Accu-Stat Home Drug Test for Marijuana (THC), Cocaine (COC), Amphetamine (AMP), Methamphetamine (mAMP), Opiates (OPI), and Phencyclidine (PCP)....
... Screen Tests are available in 14 configurations ... Designed using Microgenics Antibody Technology, the SureStep™ ... of care immunoassay targeted to detect MDMA ... and MDEA but no cross-reactivity to any ...
Medicine Products: