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New Stanford device could reduce surgical scarring
Date:5/23/2011

tremendous amount of tension occurred across the wound after closure. (Scars from these procedures are typically wide and thick.) Longaker said he and his colleagues deliberately chose to test the dressing on incisions closed with high tension: If the dressing could reduce scarring in such cases, it would surely work on any other kind of incision.

One side of the abdomen-wide incision on each patient was treated with the stress-shielding dressing; the other half was not. A panel of three plastic surgeons unaffiliated with the research, as well as a panel of three people not in the medical profession, acted as judges. On a 100-point scale, the lay panel scored the appearance of stress-shielded wounds an average of 13.2 points higher than the control wounds. The expert panel scored the scar appearance of the treated incisions 39.2 points higher. In both of these analyses, the difference between the treated side and the control side were highly significant, the researchers said.

But they noted that some of the wounds demonstrated more dramatic improvement than others. They speculate this may have been due to differences in the amount of tension present in the dressings when they were applied to the wounds. In any case, the researchers cautioned that this was a preliminary clinical study designed only to show "proof of principle in humans."

"Larger clinical trials are being planned to include greater ethnic diversity within the patient population and to determine the optimal range of stress-shielding forces for anatomic region- and dimension-specific wounds," the authors wrote.


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Contact: John Sanford
jsanford@stanfordmed.org
650-723-8309
Stanford University Medical Center
Source:Eurekalert

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