Navigation Links
New Spray Could Benefit Cystic Fibrosis Patients
Date:5/18/2009

Airways remained clear and moist in studies, researcher says

MONDAY, May 18 (HealthDay News) -- A new aerosol spray may help keep the airways of cystic fibrosis patients moist and clear, researchers say.

Using a special agent called GS-9411, the spray prevents sodium from being absorbed too quickly, which is a common problem for people with cystic fibrosis. The quick absorption of sodium from the surface of the airway causes their airways to dry, and allows mucous and bacteria to accumulate.

In tests on airway surface cells grown in a laboratory, GS-9411 helped the cells retain moisture for more than eight hours while tests on animals found the spray helped clear excessive mucus for at least four hours.

The findings were presented Sunday at the American Thoracic Society's annual international conference in San Diego.

"GS-9411 administered by aerosol can effectively increase airway surface liquid and enhance mucous clearance in an animal model," study author Andrew Hirsh, senior director of drug discovery and preclinical development for Parion Sciences, a pharmaceutical company, said in a news release. "The results demonstrate that GS-9411 warrants further investigation as a new drug therapy to decrease respiratory infection and improve pulmonary function."

In cystic fibrosis, a genetic defect causes the airway to absorb sodium, and therefore moisture, too quickly. When the airway is too dry, the body can't clear mucus, a key defense mechanism of the respiratory system, Hirsh said. This deficiency can cause cystic fibrosis patients to have chronic respiratory infection and impaired lung function, he explained.

"The potency and the length of time that the drug was effective in cells and in animal studies was an outstanding feature that distinguishes this compound from other agents," he said.

More information

The March of Dimes has more about

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Video: NASONEX(R) (Mometasone Furoate Monohydrate) Nasal Spray, 50 mcg* Teams Up With American Forests to Educate Nasal Allergy Sufferers and Help Improve Air Quality
2. Groundbreaking First Response Spray Now Available in Europe
3. Topical Spray Helped Men With Premature Ejaculation
4. Premature ejaculation spray enables men to last 6 times longer after penetration
5. Strativa Pharmaceuticals Acquires Worldwide Rights to Nascobal(R) (Cyanocobalamin, USP) Nasal Spray From QOL Medical
6. CSA Medical, Inc. Announces Launch of New Web Site for Spray Cryotherapy
7. Sinus Buster Pepper Nasal Spray Moves Into Rite Aid Drug Stores
8. Ocean Spray Shows Its Love for Heart Health with American Heart Association Partnership
9. Nose-spray vaccine against botulism effective in first tests
10. Ocean Spray(R) Announces Sugar-Free Drink Mixes - A Sweet Way for Dieters to Stick to Their Resolutions
11. Hairspray Exposure Ups Risk for Birth Defect in Sons
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Spray Could Benefit Cystic Fibrosis Patients
(Date:9/16/2014)... Cliff Lake Dental Care is proud to announce the latest ... to join Dr. Rauchwarter's team. The team at Cliff Lake ... she will bring many benefits to the office as well ... Falls, WI. She finished dental assisting school and graduated ... assisting in the Twin Cities, Milwaukee, California and Virginia. ...
(Date:9/16/2014)... Aspen Advisors, a U.S.-based healthcare IT ... for its high morale and collaborative culture ... Firms to Work For 2014.” Consulting magazine publishes ... 10,000 consultants participating across all major industries, representing more ... conducted, and firms were ranked in six categories - ...
(Date:9/16/2014)... as part of breast conservation is the current ... (HR+) invasive breast cancer. A new study by ... that combination may not be necessary for all ... results, which Fox Chase researchers presented at the ... on Sunday, September 14, suggest that low-risk patients ...
(Date:9/16/2014)... September 16, 2014 Seven heroes who ... world will be honored in New York City on ... ), the only global recognition and funding program that ... by the media as the “Nobel Prize for Child ... created life-changing programs that benefit children in countries around ...
(Date:9/16/2014)... Los Angeles, CA (PRWEB) September 16, 2014 ... the League of United Latin American Citizens (LULAC) will ... California. LULAC’s Feria de Salud will feature free health ... Other free testing includes glucose and cholesterol levels ... screenings will be available for children under 6 years ...
Breaking Medicine News(10 mins):Health News:Cliff Lake Dental Care Announces Newest Team Member 2Health News:Aspen Advisors Earns Recognition in Consulting Magazine’s "Best Small Firms to Work For" 2Health News:Aspen Advisors Earns Recognition in Consulting Magazine’s "Best Small Firms to Work For" 3Health News:Benefit of endocrine therapy in elderly women with low risk hormone receptor positive breast cancer? 2Health News:Benefit of endocrine therapy in elderly women with low risk hormone receptor positive breast cancer? 3Health News:World of Children® Award Announces 2014 Honorees 2Health News:World of Children® Award Announces 2014 Honorees 3Health News:World of Children® Award Announces 2014 Honorees 4Health News:World of Children® Award Announces 2014 Honorees 5Health News:World of Children® Award Announces 2014 Honorees 6Health News:World of Children® Award Announces 2014 Honorees 7Health News:World of Children® Award Announces 2014 Honorees 8Health News:LULAC Hosts Second Annual Latinos Living Healthy Feria de Salud in Los Angeles 2
... BRIDGEWATER, N.J., March 16 Sanofi-aventis U.S. announced ... to Chief Science Officer/Chief Medical Officer, U.S., effective ... sanofi-aventis, U.S. As the company,s Chief Science ... establish a unified medical voice for sanofi-aventis U.S. ...
... Training and Professional Certification ProgramsKERRY, Ireland and ... leading Ireland-based provider of innovative learning solutions, ... eLearning and certification programs for the American ... the Insurance Institute of America (the Institutes), ...
... result, studies find, , , MONDAY, March 16 (HealthDay News) ... can be successfully harnessed to deliver health information to ... encouraging them to stick more closely to the treatments ... suggests. , One study explored giving teens regular ...
... (NYSE: MHS ) Chairman and CEO David ... Luncheon Address to the American Enterprise Institute,s health care ... March 18, 2009, at 12:30 p.m. Through the ... be directed at expanding the use of health information ...
... Vitamin D, but be Careful Not to Burn Cautions Tanning ... Indoor Tanning Association (ITA) is encouraging beach goers to tan ... good health, overexposure to UV light can be a dangerous ... order for tanners to get all the benefits of UV ...
... the NCCN Clinical Practice Guidelines in Oncology(TM) for Thyroid ... 14. Notable updates include a new page on Thyroid ... molecule kinase inhibitors, and revised procedures for evaluating thyroid ... of Texas M.D. Anderson Cancer Center and chair ...
Cached Medicine News:Health News:Paul Chew Appointed to sanofi-aventis U.S. Chief Science Officer/Chief Medical Officer 2Health News:Ireland's PulseLearning Inks Agreement With Leading U.S. Insurance Industry Association 2Health News:Using Music and Sports to Improve Kids' Asthma 2Health News:Using Music and Sports to Improve Kids' Asthma 3Health News:Media Advisory: Medco CEO David B. Snow Jr. To Address American Enterprise Institute: 'Health IT: Empowering Precision Medicine' 2Health News:Indoor Tanning Association Promotes Responsible Tanning for Spring Breakers 2Health News:NCCN Presents Updates to NCCN Guidelines for Thyroid Carcinoma 2Health News:NCCN Presents Updates to NCCN Guidelines for Thyroid Carcinoma 3Health News:NCCN Presents Updates to NCCN Guidelines for Thyroid Carcinoma 4
(Date:9/16/2014)... -- A study led by St. Jude Children,s ... threshold below which male childhood cancer survivors are likely ... September 17 edition of the journal Lancet Oncology ... highest risk for reduced sperm production as adults, researchers ... fertility preservation methods such as sperm banking. ...
(Date:9/16/2014)... The Pulmonary Fibrosis Foundation (PFF) announced today that it ... and families suffering from pulmonary fibrosis (PF) to the ... Drug Development Meeting for Idiopathic Pulmonary Fibrosis on September ... patient input in order to better understand patients, needs ... the FDA for focusing its attention on this devastating ...
(Date:9/16/2014)... 2014 Astellas announced today it has ... & Advocacy, Urology in the Americas. Noland will report ... Margaret Long. In this role, Noland will be responsible ... and advocacy organizations, as well as collaborating with ... Noland,s appointment is the latest phase in the ...
Breaking Medicine Technology:Improved risk identification will aid fertility preservation in young male cancer patients 2Improved risk identification will aid fertility preservation in young male cancer patients 3Improved risk identification will aid fertility preservation in young male cancer patients 4PFF Submits Survey Data From More Than 1,100 Pulmonary Fibrosis Patients And Families To U.S. Food And Drug Administration For Upcoming Drug Development Meeting 2PFF Submits Survey Data From More Than 1,100 Pulmonary Fibrosis Patients And Families To U.S. Food And Drug Administration For Upcoming Drug Development Meeting 3PFF Submits Survey Data From More Than 1,100 Pulmonary Fibrosis Patients And Families To U.S. Food And Drug Administration For Upcoming Drug Development Meeting 4Christy Noland to Lead Urology Advocacy and Communications for Astellas 2
... HistoRx, Inc. (privately held), a diagnostics company, announced ... of clinical diagnostic assays based on AQUA® technology. ... specialized laboratory service provider, is launching NexCourse®(1) BCa ... assays based on quantitative immunohistochemistry.  NexCourse BCa by ...
... SHANGHAI, Nov. 12, 2010 /PRNewswire-Asia/ -- WuXi PharmaTech ... announced shareholder resolutions adopted at its annual general ... November 10, 2010. (Logo: http://photos.prnewswire.com/prnh/20040705/CNM002LOGO) ... the meeting, WuXi PharmaTech shareholders approved the re-election ...
Cached Medicine Technology:HistoRx Announces First Clinical Diagnostic Use of AQUA® Technology 2HistoRx Announces First Clinical Diagnostic Use of AQUA® Technology 3WuXi PharmaTech Announces Shareholder Resolutions Adopted at 2010 Annual General Meeting 2
19 Gauge. Reusable. Block of 4 each....
18 gauge curved. Fine tip. Lightweight design offers precise hemostasis. Pencil design minimizes tissue trauma and induced astigmatism. Knurled handle provides a sure grip and better manipulation....
Set consist of two 23 gauge, stainless steel probes with blunt tips. Probes are 18 cm (7.0 inches) long with 30.5 cm (12 inches) of flexible tubing (O.D. - 0.60 mm, I.D. - 0.30 mm) attached onto the ...
Curved, soft flexible tip allows atraumatic entry through a retinal tear or hole for aspiration of subretinal fluids. 20 gauge x 25 mm cannula attached to 25 gauge x 6 mm tip with 13 mm flexible tubi...
Medicine Products: