Navigation Links
New Scan Spots Beginning of Bone Problems in Anorexics
Date:11/19/2008

Structural abnormalities start early, researchers report

WEDNESDAY, Nov. 19 (HealthDay News) -- A new scanning technology has detected previously unnoticed bone abnormalities in adolescent girls afflicted with the eating disorder anorexia.

"What we have found in this study is an exciting new thing," said Dr. Miriam A. Bredella, lead author of a report in the December issue of Radiology. "Prior studies have shown only decreased bone density. We show abnormalities of bone structure. Our data suggest that tests showing normal values of bone density in these adolescents do not reflect the true status of bone structure."

The new study "shows that the quality of bone in women with anorexia is not normal, which is something we have suspected for a while, because they fracture even with normal bones," said Dr. Michelle Warren, a professor of medicine and obstetrics and gynecology at Columbia University, who has done studies of her own on the subject.

"This CT methodology is new and gives better knowledge about what is going on in the bones, because it gives information about their architecture," Warren said.

In terms of medical treatment of women with anorexia, "it shows that we really should pay more attention not only to the absolute value of the bones, but also to how much weight an individual has lost," she said.

Anorexia is characterized by a distorted body image and intense fear of gaining weight that leads to dangerous food deprivation. It occurs primarily in young women, affecting perhaps one of every 100 adolescent girls, according to the U.S. National Women's Health Information Center.

Bone studies in anorexia typically use X-rays. The newly reported research used a technique called high-resolution, flat-panel volume computer tomography to compare the bones of 10 girls, aged 13 to 18, with mild anorexia with those of 10 age-matched girls without the eating disorder.

"This is a CT scan that makes very thin slices of bone to see bone structure," said Bredella, who is an assistant professor of radiology at Harvard Medical School and a musculoskeletal radiologist at Massachusetts General Hospital. "It uses a low dose of radiation, about the same as from the background radiation over a three-day period."

The CT scans showed no significant difference in bone mineral density in the two groups. They did show significant structural differences, indicating that the first bone problems in anorexia begin before changes in bone density can be detected.

"There can be early or mild already abnormal bone structure, while bone density appears normal," Bredella said.

Early detection of bone problems is desirable, because "deficits in adolescence result in low peak bone mass and increased risk of fracture in adult life," Bredella said. "It can be done with a modality that evaluates bone structure as well as density."

Tests to detect changes in bone structure might be done "if an adolescent has the disease for a while, and it is not getting better," she said. While the flat-panel volume CT scan used by her group is not widely available, other CT scans in wide clinical use can detect bone structure abnormalities, Bredella said.

There are established treatments, such as low-dose testosterone, that can be used to treat bone disorders in anorexia, she said.

More information

Anorexia, its effects and treatment, are described by the U.S. National Women's Health Information Center.



SOURCES: Miriam A. Bredella, M.D., assistant professor, radiology, Harvard Medical School, Boston; Michelle Warren, professor, medicine, and obstetrics and gynecology, Columbia University, New York City; December 2008, Radiology


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Rainier Spots Show Higher Autism Rates
2. Special Mouth Rinse Spots, Tracks Human Papillomavirus Infection
3. First-Ever National Ranking of Hot Spots for Peripheral Artery Disease (P.A.D.) Identifies Cities With Higher Risk of Heart Attack and Stroke
4. Age Spots Are No Match for Cosmetic Dermatology Treatments
5. Mental Test Spots Alzheimers Risk
6. Cholesterol Test Spots When HRT Raises Heart Risks
7. Six Youths Secure Top Spots in American Humane Kind Kid Contest
8. Biomarker Spots Which Lesions Likely to Progress to Prostate Cancer
9. Skin Test Spots Heart Risks in Healthy People
10. Study Spots Gene That Plays Role in Infertility
11. Microchip Spots Stray Tumor Cells in the Bloodstream
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Scan Spots Beginning of Bone Problems in Anorexics
(Date:6/27/2016)... ... 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to Best ... individuals in the United States and Canada wear eyeglasses. Once considered to be a ... and make a fashion statement. Even celebrities use glasses as a way of creating ...
(Date:6/26/2016)... NC (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind and ... to be personalized through a fitness app. The fitness app plans to fix the two ... currently only offer a one size fits all type program , They don’t ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, ... Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms ... Final Cut Pro X . Simply select a ProHand generator and drag it above ...
(Date:6/25/2016)... ... , ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter ... bar too high can result in disappointment, perhaps even self-loathing. However, those who set ... , Research from PsychTests.com reveals that behind the tendency to set low ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... and Scientific Sessions in Dallas that it will receive two significant new grants ... grants came as PHA marked its 25th anniversary by recognizing patients, medical professionals ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) ... Improvements Act of 1976, as amended ("HSR"), with respect ... Nasdaq: CPXX ) expired effective June 24, ... As previously announced on May 31, 2016, Jazz Pharmaceuticals ... which Jazz Pharmaceuticals has commenced a tender offer for ...
(Date:6/26/2016)... , June 26, 2016 ... value-based care operating models within the health care industry ... greater financial efficiency , Deloitte offers a suite ... key business issues impacting efficient cost optimization: labor resource ... , These services facilitate better outcomes and better economics ...
(Date:6/24/2016)... , June 24, 2016  Collagen Matrix, Inc., ... development and manufacturing of collagen and mineral based ... today that Bill Messer has joined ... to further leverage the growing portfolio of oral ... Bill joins the Collagen Matrix executive ...
Breaking Medicine Technology: