Navigation Links
New Scan Spots Beginning of Bone Problems in Anorexics

Structural abnormalities start early, researchers report

WEDNESDAY, Nov. 19 (HealthDay News) -- A new scanning technology has detected previously unnoticed bone abnormalities in adolescent girls afflicted with the eating disorder anorexia.

"What we have found in this study is an exciting new thing," said Dr. Miriam A. Bredella, lead author of a report in the December issue of Radiology. "Prior studies have shown only decreased bone density. We show abnormalities of bone structure. Our data suggest that tests showing normal values of bone density in these adolescents do not reflect the true status of bone structure."

The new study "shows that the quality of bone in women with anorexia is not normal, which is something we have suspected for a while, because they fracture even with normal bones," said Dr. Michelle Warren, a professor of medicine and obstetrics and gynecology at Columbia University, who has done studies of her own on the subject.

"This CT methodology is new and gives better knowledge about what is going on in the bones, because it gives information about their architecture," Warren said.

In terms of medical treatment of women with anorexia, "it shows that we really should pay more attention not only to the absolute value of the bones, but also to how much weight an individual has lost," she said.

Anorexia is characterized by a distorted body image and intense fear of gaining weight that leads to dangerous food deprivation. It occurs primarily in young women, affecting perhaps one of every 100 adolescent girls, according to the U.S. National Women's Health Information Center.

Bone studies in anorexia typically use X-rays. The newly reported research used a technique called high-resolution, flat-panel volume computer tomography to compare the bones of 10 girls, aged 13 to 18, with mild anorexia with those of 10 age-matched girls without the eating disorder.

"This is a CT scan that makes very thin slices of bone to see bone structure," said Bredella, who is an assistant professor of radiology at Harvard Medical School and a musculoskeletal radiologist at Massachusetts General Hospital. "It uses a low dose of radiation, about the same as from the background radiation over a three-day period."

The CT scans showed no significant difference in bone mineral density in the two groups. They did show significant structural differences, indicating that the first bone problems in anorexia begin before changes in bone density can be detected.

"There can be early or mild already abnormal bone structure, while bone density appears normal," Bredella said.

Early detection of bone problems is desirable, because "deficits in adolescence result in low peak bone mass and increased risk of fracture in adult life," Bredella said. "It can be done with a modality that evaluates bone structure as well as density."

Tests to detect changes in bone structure might be done "if an adolescent has the disease for a while, and it is not getting better," she said. While the flat-panel volume CT scan used by her group is not widely available, other CT scans in wide clinical use can detect bone structure abnormalities, Bredella said.

There are established treatments, such as low-dose testosterone, that can be used to treat bone disorders in anorexia, she said.

More information

Anorexia, its effects and treatment, are described by the U.S. National Women's Health Information Center.

SOURCES: Miriam A. Bredella, M.D., assistant professor, radiology, Harvard Medical School, Boston; Michelle Warren, professor, medicine, and obstetrics and gynecology, Columbia University, New York City; December 2008, Radiology

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Rainier Spots Show Higher Autism Rates
2. Special Mouth Rinse Spots, Tracks Human Papillomavirus Infection
3. First-Ever National Ranking of Hot Spots for Peripheral Artery Disease (P.A.D.) Identifies Cities With Higher Risk of Heart Attack and Stroke
4. Age Spots Are No Match for Cosmetic Dermatology Treatments
5. Mental Test Spots Alzheimers Risk
6. Cholesterol Test Spots When HRT Raises Heart Risks
7. Six Youths Secure Top Spots in American Humane Kind Kid Contest
8. Biomarker Spots Which Lesions Likely to Progress to Prostate Cancer
9. Skin Test Spots Heart Risks in Healthy People
10. Study Spots Gene That Plays Role in Infertility
11. Microchip Spots Stray Tumor Cells in the Bloodstream
Post Your Comments:
Related Image:
New Scan Spots Beginning of Bone Problems in Anorexics
(Date:11/25/2015)... ... 2015 , ... Beddit® has launched a new Android app for ... features a more intuitive SleepScore™ that rates sleep quality on a 100-point scale and ... created by a proprietary algorithm. Beddit analyzes the data to provide an easy to ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... for people struggling with eating disorders as a result of the $20,000 raised ... event, held at Fox Run Golf Club in Eureka, will help individuals who ...
(Date:11/25/2015)... ... 2015 , ... Many people know of the common symptoms of low thyroid ... skin. But many people who find their cholesterol levels and weight are creeping up ... especially if they don’t have any of the other symptoms. , Thyroid hormone plays ...
(Date:11/24/2015)... Florida (PRWEB) , ... November 25, 2015 , ... ... planning and monitoring. Their Care Plan software creates an agreement between the ... patient care plan, including financial, scheduling, monitoring, notification, and projections. Click ...
(Date:11/24/2015)... ... ... Charitable giving is at its peak during the holidays. In fact, nearly ... year totalling over $358 billion in 2014. With more than 1.5 million U.S. ... who want to “give back” during the holidays. , “With so many charities to ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... Calif. , Nov. 24, 2015 /PRNewswire/ ... leader in non-invasive genetic testing and the ... that it will present at the 27 ... York on Wednesday, December 2, 2015 at 1:00 p.m. ET.  Matthew Rabinowitz, ... Company,s financial results, business activities and financial ...
(Date:11/24/2015)... November 2015 Avery Biomedical Devices ... ist erfreut, die Berufung von Anders Jonzon, ... zu können.   ... Foto -   ... 1984-1986 war er Fellow des Cardiovascular Institute ...
(Date:11/24/2015)... 2015   HeartWare International, Inc . (NASDAQ: ... support technologies that are revolutionizing the treatment of advanced ... Officer Doug Godshall is scheduled to present ... Conference on December 1, 2015 at 3:00 p.m. ET.  ... New York . ...
Breaking Medicine Technology: