Navigation Links
New Scan 'Sees' Tumors Deep Inside Body
Date:4/2/2008

Imaging technique could help surgeons remove all cancerous tissue

WEDNESDAY, April 2 (HealthDay News) -- Stanford University researchers have developed a new imaging system that illuminates tumors deep inside the body and lets doctors view details 1,000 times smaller than previously possible.

Raman spectroscopy uses tiny nanoparticles injected into the body to serve as beacons for lasers, according to a description the method published in this week's online issue of the Proceedings of the National Academy of Sciences.

When a laser beam outside the body hits them, the specialized particles emit signals that can be converted into a visible indicator of their location in the body. These strong, long-lived signals can simultaneously transmit information about multiple molecular targets.

"Usually we can measure one or two things at a time," senior author Dr. Sanjiv Sam Gambhir, a professor of radiology at Stanford's School of Medicine, said in a prepared statement. "With this, we can now likely see 10, 20, 30 things at once."

The new system utilizes the Raman effect, which occurs when light is shined on an object. The light causes roughly one in 10 million photons to bounce off the object's molecules with an increase or decrease in energy, called Raman scattering. This forms a unique measurable pattern, called a spectral fingerprint, for each type of molecule.

The Stanford research team tested the system on mice, injecting them with various engineered Raman nanoparticles and then viewing the anesthetized mice under a special microscope where they were exposed to laser light. The nanoparticles, for example, would be "tagged" with different pieces of proteins that sought out different tumor molecules.

In these experiments, the team spotted targets 1,000 times smaller than what is viewable with the most precise fluorescence imaging available. Since the Raman effect lasts indefinitely, as long as the particles stay in the body they can work as signals.

Because of these findings, the technique could be useful during tumor surgery on humans by aiding in the removal of even the most microscopic bits of cancerous tissue, the researchers said.

Gambhir's lab is further studying these Raman nanoparticles, including optimizing their size and dosage and evaluating possible toxicity. A clinical trial using gold nanoparticles in humans in conjunction with a colonoscopy to indicate early-stage colorectal cancer is being planned.

More information

The U.S. National Library of Medicine and the National Institutes of Health has more about diagnostic imaging techniques.



-- Kevin McKeever



SOURCE: Stanford University Medical Center, news release, March 31, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Hypnosis for smoking cessation sees strong results
2. Chemmart(R) Sees Instant Results From Launch of New Rewards Program
3. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
4. Study suggests brain tumors need treatment with multiple targeted drugs
5. Bright tumors, dim prospects
6. Genomic profiling of lung tumors helps doctors choose most effective treatment
7. Gene Tests Match Up Lung Tumors, Best Treatment
8. Endoscopic resection is a safe and effective treatment for gastrointestinal smooth muscle tumors
9. New seed therapy helps pinpoint breast tumors with more accuracy
10. Study suggests existing drugs may be useful in treating brain tumors
11. U.S. Oncology Initiates Complete Phase Ib Trial of Brostallicin Combination Therapy in Advanced Solid Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Scan 'Sees' Tumors Deep Inside Body
(Date:5/2/2016)... , ... May 02, 2016 , ... ... a residential inpatient rehabilitation center can find some useful information in a new ... in Central Michigan. This video, which can be viewed on the Serenity Recovery ...
(Date:5/2/2016)... ... 2016 , ... Beanfields, PBC, makers of Beanfields Bean and ... at University of Colorado in Boulder to create new advertising campaigns. , Adjunct ... School of Journalism, who selected Beanfields as the brand on which to focus ...
(Date:5/2/2016)... Texas (PRWEB) , ... May 02, 2016 , ... In ... will offer an incentive to people who share their fitness journey on social ... and premium first aid products, will award a $100 product voucher each week during ...
(Date:5/2/2016)... ... 2016 , ... East Los Angeles dentist , Dr. Ramin Assili, is ... to receive any dental extraction treatment for $40 off the regular price. This promotion ... the lower price, patients can more easily afford extractions to eliminate teeth that are ...
(Date:5/2/2016)... ... ... Dr. Rassouli, dentist in Orange County, CA comments on the ... was published in the “Journal of the American Geriatrics Society,” more than a third ... Alzheimer’s disease. The study found that dental problems may increase the risk of heart ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... 2016 Treato , the ... announced today that it has been named a Cool ... in Life Sciences, 2016, Stephen Davies , ... focuses on life-science- oriented analytics, algorithms and smart machine ... doctors, confirm medication ingestion, and analyze unstructured information.   ...
(Date:4/28/2016)... Dr. Vivek Ahuja , ... Ste phen Schmidt ... of cloud-based software solutions for life sciences, today announced key new ... wealth of insight to a growing business.  This will bolster the ... George Phillips joined ArisGlobal in the position of Vice President ...
(Date:4/28/2016)... N.J. , April 28, 2016   Acsis ... today announced that leading IT market research and advisory ... " in the IDC MarketScape: Worldwide Pharmaceutical Track and ... 2016).  The report provides an assessment of the capabilities ... track and trace software market. Logo - ...
Breaking Medicine Technology: