Navigation Links
New Scan 'Sees' Tumors Deep Inside Body
Date:4/2/2008

Imaging technique could help surgeons remove all cancerous tissue

WEDNESDAY, April 2 (HealthDay News) -- Stanford University researchers have developed a new imaging system that illuminates tumors deep inside the body and lets doctors view details 1,000 times smaller than previously possible.

Raman spectroscopy uses tiny nanoparticles injected into the body to serve as beacons for lasers, according to a description the method published in this week's online issue of the Proceedings of the National Academy of Sciences.

When a laser beam outside the body hits them, the specialized particles emit signals that can be converted into a visible indicator of their location in the body. These strong, long-lived signals can simultaneously transmit information about multiple molecular targets.

"Usually we can measure one or two things at a time," senior author Dr. Sanjiv Sam Gambhir, a professor of radiology at Stanford's School of Medicine, said in a prepared statement. "With this, we can now likely see 10, 20, 30 things at once."

The new system utilizes the Raman effect, which occurs when light is shined on an object. The light causes roughly one in 10 million photons to bounce off the object's molecules with an increase or decrease in energy, called Raman scattering. This forms a unique measurable pattern, called a spectral fingerprint, for each type of molecule.

The Stanford research team tested the system on mice, injecting them with various engineered Raman nanoparticles and then viewing the anesthetized mice under a special microscope where they were exposed to laser light. The nanoparticles, for example, would be "tagged" with different pieces of proteins that sought out different tumor molecules.

In these experiments, the team spotted targets 1,000 times smaller than what is viewable with the most precise fluorescence imaging available. Since the Raman effect lasts indefinitely, as long as the particles stay in the body they can work as signals.

Because of these findings, the technique could be useful during tumor surgery on humans by aiding in the removal of even the most microscopic bits of cancerous tissue, the researchers said.

Gambhir's lab is further studying these Raman nanoparticles, including optimizing their size and dosage and evaluating possible toxicity. A clinical trial using gold nanoparticles in humans in conjunction with a colonoscopy to indicate early-stage colorectal cancer is being planned.

More information

The U.S. National Library of Medicine and the National Institutes of Health has more about diagnostic imaging techniques.



-- Kevin McKeever



SOURCE: Stanford University Medical Center, news release, March 31, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Hypnosis for smoking cessation sees strong results
2. Chemmart(R) Sees Instant Results From Launch of New Rewards Program
3. Tumors use enzyme to recruit regulatory T-cells and suppress immune response
4. Study suggests brain tumors need treatment with multiple targeted drugs
5. Bright tumors, dim prospects
6. Genomic profiling of lung tumors helps doctors choose most effective treatment
7. Gene Tests Match Up Lung Tumors, Best Treatment
8. Endoscopic resection is a safe and effective treatment for gastrointestinal smooth muscle tumors
9. New seed therapy helps pinpoint breast tumors with more accuracy
10. Study suggests existing drugs may be useful in treating brain tumors
11. U.S. Oncology Initiates Complete Phase Ib Trial of Brostallicin Combination Therapy in Advanced Solid Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Scan 'Sees' Tumors Deep Inside Body
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/24/2016)... Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... surgery procedures that most people are unfamiliar with. The article goes on to state ... procedures, but also many of these less common operations such as calf and cheek ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Marcy was in a crisis. Her son James, ... out at his family verbally and physically. , “When something upset him, he couldn’t control ... use it. He would throw rocks at my other children and say he was going ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda ... orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including ... accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening ... Talker Award, an essay contest in which patients and their families pay tribute to ... at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Bracket , ... launch its next generation clinical outcomes platform, Bracket eCOA (SM) ... held on June 26 – 30, 2016 in ... first electronic Clinical Outcome Assessment product of its kind to ... #715. Bracket eCOA 6.0 is a flexible platform ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 ... Tomorrow,s Leaders Scholarship is any indication, the future is ... online at www.diabetesscholars.org by the Diabetes Scholars ... in the way of academic and community service excellence. ... program since 2012, and continues to advocate for people ...
(Date:6/23/2016)... 2016 Revolutionary technology includes multi-speaker ... , industry leaders in advanced audiology and hearing aid ... Opn ™, the world,s first internet connected hearing aid ... devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) ... of ,world firsts,: , TwinLink™ - the ...
Breaking Medicine Technology: