Navigation Links
New STELARA data show inhibition of joint destruction in active psoriatic arthritis
Date:10/28/2013

San Diego, October 28, 2013 -- New findings from two integrated Phase 3 Janssen Research & Development, LLC (Janssen)-sponsored studies showed treatment with STELARA (ustekinumab) resulted in significantly greater inhibition of structural damage in patients with active psoriatic arthritis compared with placebo. Pre-specified integrated analyses from the PSUMMIT I and II trials showed treatment with either STELARA 45 mg or 90 mg resulted in significantly less change from baseline at week 24 in total psoriatic arthritis modified van der Heijde-Sharp (vdH-S) scores compared with placebo. STELARA-treated patients from the combined data analysis of both trials demonstrated continued inhibition through one year and through two years according to findings from the PSUMMIT I trial. These results are being presented during the 2013 Annual Meeting of the American College of Rheumatology (ACR). STELARA recently received approval from the U.S. Food and Drug Administration (FDA) and approval from the European Commission for the treatment of signs and symptoms in adult patients with active psoriatic arthritis.

"Data from the integrated analysis of the Phase 3 clinical program show the efficacy of the interleukin-12/23 antibody STELARA in inhibiting the progression of structural damage in patients with active psoriatic arthritis," said Iain B. McInnes, PhD, FRCP, Professor of Medicine, and Director of the Institute of Infection, Immunity, and Inflammation, University of Glasgow, Scotland, lead study investigator. "These new findings are significant since impeding further joint damage is an important part of the long-term management of this chronic inflammatory disease."

According to a pre-specified integrated analysis of the two Phase 3 Multicenter, Randomised, Double-blind, Placebo-controlled trials of Ustekinumab, a Fully Human anti-IL-12/23p40 Monoclonal Antibody, Administered Subcutaneously, in Subjects with Active Psoriatic Arthritis (PSUMMIT I
'/>"/>

Contact: Brian Kenney
BKenney1@its.jnj.com
215-628-7010
Tonic Life Communications USA
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Alzheimer's Pilot Study Proposed for Ustekinumab (Stelara)
2. Specific inhibition of autophagy may represent a new concept for treatment of kidney cancer
3. Treating drug resistant cancer through targeted inhibition of sphingosine kinase
4. Novel test identifies patients most likely to benefit from ALK inhibition therapy
5. Neurological Wellness Center's Novel Neuro-Inflammation Inhibition Procedure that Induces Rapid Recovery from Alzheimer's, Stroke and Brain Injury is Now Being Taught in a Newly Released Video
6. Epoxide hydrolase inhibition and Thiazolidinediones: A therapy for cardiometabolic syndrome
7. Joint-Replacement Failure Rate Higher for Smokers: Studies
8. Soy-based S-equol supplement reduces hot flash frequency, muscle & joint pain in US women
9. Obesity, Diabetes May Raise Complications After Joint Replacement
10. Oxford University Press acquires joint ownership of Journal of Surgical Case Reports
11. Joint Replacement Boosts Heart Attack Risk Right After Surgery: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... , ... August 28, 2015 ... ... for Medical Devices:, Understanding the FDA’s Position and Best Practices for Compliance, ... http://www.fdanews.com/cybersecuritymd , This workshop, chaired by internationally renowned expert Fubin Wu, ...
(Date:8/28/2015)... ... August 28, 2015 , ... On May 30th, 2015, Best Drug Rehabilitation, ... the “Music With A Mission” benefit concert in Mendon, IL. Held in the Show ... money to support music education programs in the underfunded local school districts of Mendon ...
(Date:8/28/2015)... , ... August 28, 2015 , ... “ Frequentz ” ... at the latest and coolest applications on the market for iOS, Android, and Windows. ... shared with viewers how this software allows businesses to track product movement from beginning ...
(Date:8/28/2015)... ... 28, 2015 , ... Medical Solutions, one of the nation’s largest travel nurse ... Healthcare by Modern Healthcare and will be honored at an awards dinner in ... the Best Places to Work in Healthcare program recognizes outstanding employers in the healthcare ...
(Date:8/28/2015)... (PRWEB) , ... August 28, 2015 , ... Dr. Gregory ... such as radiating pain resulting in shoulder pain, hip pain, neck pain, ... in Civil Engineering from the University of Illinois, and then went on to earn ...
Breaking Medicine News(10 mins):Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 2Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 3Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 4Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 5Health News:New Video Released on "Music With A Mission" Benefit Concert Headlining Artist Cadillac Three & Best Drug Rehabilitation 2Health News:Track Product Movement from Beginning to End with Frequentz 2Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 2Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 3Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 2Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 3
... smoke, eating habits and sleep patterns as potential causes, , , ... be the only risks that firefighters face. They also appear ... to have prematurely narrowed arteries, increasing their risk for strokes ... fact, 22 percent of a group of 77 firefighters studied ...
... March 13 North Carolina students interested in earning the doctor ... Conferences sponsored by College Foundation of North Carolina and the N.C. ... around the state:, , ... University (Greenville, NC) - 10:00 a.m. - ...
... is more difficult to recognize and treat epilepsy in ... of Deutsches rzteblatt International ( Dtsch Arztebl ... the Epilepsy Center of Johannes Gutenberg University in Mainz, ... the therapeutic options. , It is often not ...
... beneficial, but physicians need to be prudent when ... Thomas A. D,Amico, MD, of Duke Comprehensive Cancer ... controversies of minimally invasive alternatives as well as ... NCCN 14th Annual Conference. HOLLYWOOD, Fla., March 13 ...
... are roadblocks to smartest decision, report says , , FRIDAY, ... staggering choices of drug plans available through Medicare don,t ... report says. , The report found that the more ... let people pick the best value for their individual ...
... CRANBURY, N.J., March 13 Palatin Technologies, Inc. (NYSE ... will present at the Cowen and Company 29th Annual ... Copley Place on Thursday, March 19, 2009 at 11:05 ... Palatin Technologies, will provide an update on the Company,s ...
Cached Medicine News:Health News:Firefighters Have Narrower-Than-Normal Arteries, Study Finds 2Health News:Firefighters Have Narrower-Than-Normal Arteries, Study Finds 3Health News:Optometry Career Conferences Set for Five N.C. Campuses in March 2Health News:Is Smaller Better? Minimally Invasive Oncologic Surgery Options Discussed at NCCN Conference 2Health News:Is Smaller Better? Minimally Invasive Oncologic Surgery Options Discussed at NCCN Conference 3Health News:Is Smaller Better? Minimally Invasive Oncologic Surgery Options Discussed at NCCN Conference 4Health News:Many Seniors Not Selecting Lowest Cost Medicare Drug Plans 2Health News:Many Seniors Not Selecting Lowest Cost Medicare Drug Plans 3Health News:Palatin Technologies to Present at Cowen Annual Health Care Conference on March 19, 2009 2
(Date:8/27/2015)... , Aug. 27, 2015 ieCrowd™ today ... the commercial development of the company,s supplemental oxygen ... Oxygen device, being developed by ieCrowd,s subsidiary Smart ... patient,s changing demand for oxygen based on level ... (k) submission for the Smart Oxygen device would ...
(Date:8/27/2015)... Lilly and Company (NYSE: LLY ) will attend ... 17, 2015. Sue Mahony , Ph.D., senior vice ... Gaynor , M.D., senior vice president of product development ... a fireside chat at 3:30 p.m., Eastern Daylight Time. ... available on the "Webcasts & Presentations" section of Lilly,s ...
(Date:8/27/2015)... , Aug. 27, 2015   Women Grow , the ... industry, is partnering with the Cannabis World Congress & ... to produce 15 business-focused educational sessions. CWCBExpo in LA ... Los Angeles Convention Center in Los ... on the West Coast for the marijuana industry. ...
Breaking Medicine Technology:Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 2Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 3Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 4Lilly to Participate in Morgan Stanley Global Healthcare Conference 2Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 2Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 3Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 4
... April 6, 2012 The 99 Cents Only Stores is ... campaign by promoting to the broader LA community the ... carried regularly in 99 Cents Only Stores. In the ... and the American Red Cross are urging the Los ...
... 6, 2012 Ameritox(SM), the nation,s leader in pain ... Inc. (Operation UNITE), the organizers of the inaugural National ... national forum to address the prescription drug abuse epidemic. ... Florida. "As the nation,s leader in ...
Cached Medicine Technology:99 Cents Only Stores Partners with the Red Cross to Help Local Residents Prepare for the Big One 2Ameritox Commends Operation UNITE on Its Inaugural National Rx Drug Abuse Summit 2Ameritox Commends Operation UNITE on Its Inaugural National Rx Drug Abuse Summit 3
... in the field of point of diagnostics pathology, ... a back-up instrument in routine pathology laboratories. With ... for the cover, the CM1100 can be transported ... transformer, it can be run on a car ...
... the world's smallest cryostat! It is a small, ... handwheel or lever operation. The compact chamber ensures ... decontaminating agents. An insulated cover is used to ... to reduce frosting when the unit is not ...
The HM 550 series is a uniquely progressive concept for use with frozen specimens of all types. User applications define module selection and make even serial sectioning enjoyable....
... The HM 560 Cryo-Star - a ... been incorporated which offer the users ... optionally motorized cryostat with retraction that ... independent specimen and knife cooling. This ...
Medicine Products: