Navigation Links
New Research Finds Genetic Variables Impact Chemotherapy Response, According to Surviving Mesothelioma
Date:7/11/2014

Raleigh, NC (PRWEB) July 11, 2014

Cancer researchers in Slovenia say genetic variations called polymorphisms appear to have a significant impact on how patients respond to treatment with pemetrexed (Alimta), the most popular chemotherapy drug for mesothelioma. Surviving Mesothelioma has the full story. Click here to read the new post now.

Researchers at the University of Ljubljana and the Ljubljana Institute of Oncology tested mesothelioma patients on pemetrexed for different types of polymorphisms. They found that patients with genetic variations in the folate pathway or on certain transporter genes responded differently to pemetrexed than patients without these variations.

According to lead researcher Katja Goricar, a pharmacogeneticist with the Institute of Biochemistry at the University of Ljubljana, “These polymorphisms could serve as potential markers of pemetrexed treatment outcome in patients with malignant pleural mesothelioma.”

The study in Radiology and Oncology linked polymorphisms to longer or shorter survival, as well as liver and gastrointestinal toxicities.

“Without biomarkers for guidance, chemotherapy can be very ‘hit or miss’ in terms of its effectiveness,” says Surviving Mesothelioma Managing Editor Alex Strauss. “This research is encouraging news that mesothelioma treatment will continue to become more targeted and more effective.”

For a better understanding of how genetic differences may effect drug response, see Genetic Variables Impact Mesothelioma Chemotherapy Response, available now on the Surviving Mesothelioma website.

Goricar, K, et al, “Polymorphisms in folate pathway and pemetrexed treatment outcome in patients with malignant pleural mesothelioma”, April 25, 2014, Radiology and Oncology, pp. 163-172, http://www.ncbi.nlm.nih.gov/pubmed/24991206

For nearly ten years, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.

Read the full story at http://www.prweb.com/releases/2014/07/prweb12004532.htm.


'/>"/>
Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Related medicine news :

1. China Car Electric Window Regulator Industry to Grow at CAGR of 10% to 2017 Says a New Research Report at ChinaMarketResearchReports.com
2. Cholesterol Industry 2014 Development Trends in Global & China Regions in a New Research Study Available at DeepResearchReports.com
3. Chinese Blood Product Industry Report 2014-2017 Focuses Plasma Volume & Stations Says A New Research Available at ChinaMarketResearchReports.com
4. Researchers See Link Between Dyslexia, Abuse
5. Mississippi Baby now has detectable HIV, researchers find
6. World interest in research work on the benefits of the Okra plant
7. Wake-up call for more research into cell metabolism
8. Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses
9. BU researchers relate arrests with HIV risk environment
10. UI researchers find early predictor for preeclampsia
11. Advances in mollusk parasite culturing methods drives research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are recognized ... this recognition are considered among the top 2 percent of lawyers practicing within the ... this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, Burt ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, ... minimum wage raise to $12 an hour by 2020 and then adjusting it yearly to ... value of the minimum wage, assure the wage floor does not erode again, and make ...
(Date:6/24/2016)... New York, NY (PRWEB) , ... June 24, ... ... lifestyle publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as ... believes that “the most beautiful women in the world, and the most handsome ...
(Date:6/24/2016)... ... 2016 , ... National recruitment firm Slone Partners is pleased to ... genomics experience, as Vice President of North American Capital Sales at HTG Molecular ... the sales team in the commercialization of the HTG EdgeSeq system and associated reagents ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on the ... announced that patient enrollment in its ongoing randomized ... has exceeded 50% of its 24-patient target. Capricor ... the third quarter of 2016, and to report ...
(Date:6/23/2016)... RIDGE, Ill. and INDIANAPOLIS ... of students receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship ... The 2016 scholarship winners, announced today online at ... to let type 1 diabetes stand in the way ... Diabetes has supported the Foundation,s scholarship program since 2012, ...
(Date:6/23/2016)... Pa. , June 23, 2016 The ... in an outpatient dialysis facility.  Treatments are usually 3 ... 6 hours per visit, including travel time, equipment preparation ... a patient, but especially grueling for patients who are ... of a skilled nursing and rehabilitation centers for some ...
Breaking Medicine Technology: