Navigation Links
New Research Finds Genetic Variables Impact Chemotherapy Response, According to Surviving Mesothelioma
Date:7/11/2014

Raleigh, NC (PRWEB) July 11, 2014

Cancer researchers in Slovenia say genetic variations called polymorphisms appear to have a significant impact on how patients respond to treatment with pemetrexed (Alimta), the most popular chemotherapy drug for mesothelioma. Surviving Mesothelioma has the full story. Click here to read the new post now.

Researchers at the University of Ljubljana and the Ljubljana Institute of Oncology tested mesothelioma patients on pemetrexed for different types of polymorphisms. They found that patients with genetic variations in the folate pathway or on certain transporter genes responded differently to pemetrexed than patients without these variations.

According to lead researcher Katja Goricar, a pharmacogeneticist with the Institute of Biochemistry at the University of Ljubljana, “These polymorphisms could serve as potential markers of pemetrexed treatment outcome in patients with malignant pleural mesothelioma.”

The study in Radiology and Oncology linked polymorphisms to longer or shorter survival, as well as liver and gastrointestinal toxicities.

“Without biomarkers for guidance, chemotherapy can be very ‘hit or miss’ in terms of its effectiveness,” says Surviving Mesothelioma Managing Editor Alex Strauss. “This research is encouraging news that mesothelioma treatment will continue to become more targeted and more effective.”

For a better understanding of how genetic differences may effect drug response, see Genetic Variables Impact Mesothelioma Chemotherapy Response, available now on the Surviving Mesothelioma website.

Goricar, K, et al, “Polymorphisms in folate pathway and pemetrexed treatment outcome in patients with malignant pleural mesothelioma”, April 25, 2014, Radiology and Oncology, pp. 163-172, http://www.ncbi.nlm.nih.gov/pubmed/24991206

For nearly ten years, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.

Read the full story at http://www.prweb.com/releases/2014/07/prweb12004532.htm.


'/>"/>
Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Related medicine news :

1. China Car Electric Window Regulator Industry to Grow at CAGR of 10% to 2017 Says a New Research Report at ChinaMarketResearchReports.com
2. Cholesterol Industry 2014 Development Trends in Global & China Regions in a New Research Study Available at DeepResearchReports.com
3. Chinese Blood Product Industry Report 2014-2017 Focuses Plasma Volume & Stations Says A New Research Available at ChinaMarketResearchReports.com
4. Researchers See Link Between Dyslexia, Abuse
5. Mississippi Baby now has detectable HIV, researchers find
6. World interest in research work on the benefits of the Okra plant
7. Wake-up call for more research into cell metabolism
8. Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses
9. BU researchers relate arrests with HIV risk environment
10. UI researchers find early predictor for preeclampsia
11. Advances in mollusk parasite culturing methods drives research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2017)... ... 21, 2017 , ... Hospital M&A activity slowed in the second quarter of ... acquisitions rose to 23 in the second quarter, up 15% from the 20 publicly ... announced deals in the year-ago second quarter. Only four of the transactions disclosed a ...
(Date:7/21/2017)... ... July 21, 2017 , ... ... students improve their chances of acceptance to a residency in a United States ... earned degrees outside the U.S. , According to data released by the ECFMG®, ...
(Date:7/21/2017)... (PRWEB) , ... July 21, 2017 , ... ... anterior cruciate ligament (ACL) offer patients improved quality of life five years after ... Sports Medicine’s Annual Meeting in Toronto, Ontario, Canada. The study followed patients ...
(Date:7/20/2017)... 2017 (PRWEB) , ... July ... ... global provider of enterprise-grade IT operations analytics and application performance monitoring (APM) ... of world’s largest healthcare services providers. , According to Peter Ohrenberger, sales ...
(Date:7/20/2017)... ... July 20, 2017 , ... Doctors on Liens, the leading network ... Horine Chiropractic , directed by Dr. Russell Horine, DC to their exclusive list of ... with Dr. Russell Horine serving as the clinic director and his son Dr. Lee ...
Breaking Medicine News(10 mins):
(Date:7/21/2017)... and RESEARCH TRIANGLE PARK, N.C. , ... UTHR ) announced today that it will ... market opens on Thursday, July 27, 2017. ... teleconference on Thursday, July 27, 2017, at 9:00 a.m. ... with international callers dialing 1-970-315-0533.  A rebroadcast of the ...
(Date:7/19/2017)... , July 19, 2017  Mako Medical Laboratories partnered ... the Military Family Assistance Fund (MFA) to bring 140 ... to visit with their families one last time before ... coordinate the travel and logistics needed for these soldiers. ... soldiers and their families. We just wish we could ...
(Date:7/14/2017)... 13, 2017 It should come as no surprise ... is in the midst of a crippling opioid epidemic. According ... the number of overdose deaths from opiate-based medications has quadrupled, ... a million dead from 2001 to 2015". During this time, ... has similarly quadrupled, drawing a compelling link between prescription and ...
Breaking Medicine Technology: