Navigation Links
New Research Finds Genetic Variables Impact Chemotherapy Response, According to Surviving Mesothelioma
Date:7/11/2014

Raleigh, NC (PRWEB) July 11, 2014

Cancer researchers in Slovenia say genetic variations called polymorphisms appear to have a significant impact on how patients respond to treatment with pemetrexed (Alimta), the most popular chemotherapy drug for mesothelioma. Surviving Mesothelioma has the full story. Click here to read the new post now.

Researchers at the University of Ljubljana and the Ljubljana Institute of Oncology tested mesothelioma patients on pemetrexed for different types of polymorphisms. They found that patients with genetic variations in the folate pathway or on certain transporter genes responded differently to pemetrexed than patients without these variations.

According to lead researcher Katja Goricar, a pharmacogeneticist with the Institute of Biochemistry at the University of Ljubljana, “These polymorphisms could serve as potential markers of pemetrexed treatment outcome in patients with malignant pleural mesothelioma.”

The study in Radiology and Oncology linked polymorphisms to longer or shorter survival, as well as liver and gastrointestinal toxicities.

“Without biomarkers for guidance, chemotherapy can be very ‘hit or miss’ in terms of its effectiveness,” says Surviving Mesothelioma Managing Editor Alex Strauss. “This research is encouraging news that mesothelioma treatment will continue to become more targeted and more effective.”

For a better understanding of how genetic differences may effect drug response, see Genetic Variables Impact Mesothelioma Chemotherapy Response, available now on the Surviving Mesothelioma website.

Goricar, K, et al, “Polymorphisms in folate pathway and pemetrexed treatment outcome in patients with malignant pleural mesothelioma”, April 25, 2014, Radiology and Oncology, pp. 163-172, http://www.ncbi.nlm.nih.gov/pubmed/24991206

For nearly ten years, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.

Read the full story at http://www.prweb.com/releases/2014/07/prweb12004532.htm.


'/>"/>
Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Related medicine news :

1. China Car Electric Window Regulator Industry to Grow at CAGR of 10% to 2017 Says a New Research Report at ChinaMarketResearchReports.com
2. Cholesterol Industry 2014 Development Trends in Global & China Regions in a New Research Study Available at DeepResearchReports.com
3. Chinese Blood Product Industry Report 2014-2017 Focuses Plasma Volume & Stations Says A New Research Available at ChinaMarketResearchReports.com
4. Researchers See Link Between Dyslexia, Abuse
5. Mississippi Baby now has detectable HIV, researchers find
6. World interest in research work on the benefits of the Okra plant
7. Wake-up call for more research into cell metabolism
8. Fox Chase researchers recommend updating the staging criteria for breast cancer diagnoses
9. BU researchers relate arrests with HIV risk environment
10. UI researchers find early predictor for preeclampsia
11. Advances in mollusk parasite culturing methods drives research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... February 12, 2016 , ... As a former television executive, owner Tal Rabinowitz ... no time to decompress, Rabinowitz found herself drawn to a casual meditation class while ... on her life, implementing a 20-minute-per-day meditation practice with her team. After her tenure ...
(Date:2/12/2016)... ... February 12, 2016 , ... Itopia, a leader in cloud ... Clarity Intelligence Platform (CIP) into Cielo®, a discovery, migration and cloud orchestration engine. ... their small and medium business (SMB) clients. , In recent years, ...
(Date:2/12/2016)... ... February 12, 2016 , ... The Jones Agency, a ... across eastern Texas, is launching a cooperative charity drive with the Tarrant Area Food ... more than 50,000 individuals and families in need, the Tarrant County Food Bank offers ...
(Date:2/12/2016)... ... 12, 2016 , ... Donor Network West, the organ procurement organization that heals ... with San Ramon Regional Medical Center. Under the collaboration, the first of its kind, ... accommodate a more certain time frame for donor families for the recovery of organs. ...
(Date:2/12/2016)... NY (PRWEB) , ... February 12, 2016 , ... ... of “Revolutionizing Cancer Care.” , The print component of “Revolutionizing Cancer ... Dallas, Pittsburgh/Cleveland, New York, Washington DC/Baltimore, and Seattle, with a circulation of approximately ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... 2016  This month,s issue of the Journal ... an in-depth look at various causes and consequences associated with rising ... spending, which has generated significant public outrage and calls ... Laura E. Happe , PharmD, MPH. --> ... MPH. --> In 2014 prescription drug spending ...
(Date:2/12/2016)... -- Innophos Holdings, Inc. (NASDAQ: IPHS ), a leading international ... it will host a live conference call on Tuesday, February ... quarter and full year 2015 results. ... quarter and full year results will be issued on Monday, ... --> --> The conference call can be ...
(Date:2/12/2016)... , Feb. 12, 2016   HeartWare International, Inc ... call and webcast to discuss its financial results for ... on Thursday, February 25, 2016 at 8:00 a.m. ET. ... to the conference call and webcast.  On the conference ... results, highlights from the fourth quarter and business outlook.   ...
Breaking Medicine Technology: