Navigation Links
New Proteins That Help HIV Grow Identified
Date:1/10/2008

Finding could lead to treatments for when antiviral drugs fail

THURSDAY, Jan. 10 (HealthDay News) -- Harvard researchers have identified almost 300 human proteins that help HIV propagate, creating hope for new treatments to combat the virus that causes AIDS.

Using a technique called RNA interference to screen thousands of genes, the team identified 273 human proteins, according to the study published online Jan. 10 in Science Express. These proteins could provide a way to help people with HIV when the virus develops resistance to current antiviral drugs.

"Antiviral drugs are currently doing a good job of keeping people alive, but these therapeutics all suffer from the same problem, which is that you can get resistance, so we decided to take a different approach centered on the human proteins exploited by the virus. The virus would not be able to mutate to overcome drugs that interact with these proteins," senior author Stephen Elledge, a professor in Harvard Medical School's department of genetics, said in a prepared statement.

The expanded list of proteins gives future researchers "a hypothesis generation machine," he said.

"Scientists can look at the list, predict why HIV needs a particular protein, and then test their hypothesis," Elledge explained.

He noted that immune cells -- which are targeted by HIV -- contain high concentrations of many of the 273 proteins.

"We're closing in on a systems level understanding of HIV, which opens new therapeutic avenues. We might be able to tweak various parts of the system to disrupt (HIV) propagation without making our own cells sick," Elledge said.

More information

The U.S. Centers for Disease Control and Prevention has more about HIV/AIDS.



-- Robert Preidt

<
'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Scientists get first look at how water lubricates proteins
2. 2 proteins may be survival markers in some breast cancers
3. Immune Proteins Warn of Early Lung Cancer
4. Loss of gene leads to protein splicing and buildup of toxic proteins in neurons
5. Heat shock proteins are co-opted for cancer
6. Penn study finds pro-death proteins required to regulate healthy immune function
7. Smallpox vaccine alternative identified
8. Domestic violence identified as stressor associated with smoking
9. Stem Cell Institute Correct in Rejecting Applications Over Conflicts of Interest; Institutions, Board Members Involved Must Be Identified, Consumer Advocates Say
10. Pheromones identified that trigger aggression between male mice
11. Genes identified that protect against heart damage from chemotherapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Proteins That Help HIV Grow Identified
(Date:7/13/2014)... According to the Kidney Disease Solution book review ... guide on what to do to eliminate the root ... in its review that readers can easily learn what foods ... kidney health. Vkool also informs in its Kidney Disease Solution ... kidney functions naturally. The book consists of a collection of ...
(Date:7/13/2014)... 13, 2014 A Xarelto lawsuit ... LLC to provide consumers with the most current information ... of the blood-thinning medication, as well as the ... courts around the country. The law firm is now ... suffered from life-threatening internal bleeding and related complications while ...
(Date:7/13/2014)... WA (PRWEB) July 13, 2014 ... Woolcott, who commented, “As a parent of a special ... underserved need in the Seattle community for contemporary special ... provide an important alternative to students and families in ... best practices and environment for special education. We welcome ...
(Date:7/13/2014)... Arbor, MI (PRWEB) July 13, 2014 If ... learning program he has just launched at http://www.HealthYourself101.com ... of visceral obesity. , Power has set out to ... its ill effects that’s actually – dare we say it? ... “The program,” says Power, “aims to engage the remote learner ...
(Date:7/13/2014)... July 13, 2014 According to the ... this is a comprehensive guide that features a series ... with KP (keratosis pilaris). This guide consists of ... Is Keratosis Pilaris? ,     Chapter 2: What Cause ... If I Have KP? ,     Chapter 4: Keratosis ...
Breaking Medicine News(10 mins):Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 2Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 3Health News:Xeralto Lawsuit Page Launched By Wright & Schulte LLC To Provide Information On Potential For Xarelto Bleeding Side Effects, Growing Litigation 2Health News:Xeralto Lawsuit Page Launched By Wright & Schulte LLC To Provide Information On Potential For Xarelto Bleeding Side Effects, Growing Litigation 3Health News:Xeralto Lawsuit Page Launched By Wright & Schulte LLC To Provide Information On Potential For Xarelto Bleeding Side Effects, Growing Litigation 4Health News:New Private School, Emerald City School, Founded in Downtown Seattle Now Accepting 1st to 6th Grade Students Who Learn Differently 2Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 2Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 3Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 4Health News:Living With KP Book Review Exposes Jennifer Richards' Keratosis Pilaris Guide – Vkool.com 2Health News:Living With KP Book Review Exposes Jennifer Richards' Keratosis Pilaris Guide – Vkool.com 3
... Italy, May 29th, 2008 - Children who can read and ... individual sounds within words may still be poor spellers. ... Cortex, Elizabeth Eglinton and Marian Annett, at the School of ... spellers is more likely to be right-handed than other poor ...
... Educates Consumers about Urinary Health, CROMWELL, Conn., May 29 ... (UTIs) are the second most common type,of infection in the ... year. One-third of women will be diagnosed with a UTI ... get at least one in their lifetime.(2),However, many women do ...
... Up To Three Times as Many Calories as,Hand-Held, ... Nintendo Wii, are quickly becoming the most coveted gaming,systems ... to,be helpful in encouraging youth to exercise, as profiled ... of the American College of,Sports Medicine (ACSM)., One ...
... to Remain Stable or Improve in 83% of Patients ... ... Novadaq(R) Technologies Inc.,(TSX: NDQ), a developer of real-time medical imaging and ... Hospital in Milan, Italy reported independent 12-month follow-up data,on patients treated ...
... Human immune response in wildland firefighters study to be presented ... American College ... Montana Center for Work,Physiology and Exercise Metabolism (Montana WPEM) will ... American College of Sports,Medicine, showing that wildland firefighters who consumed ...
... TOKYO, May 29 ALOKA announced today new ... the 20th Congress of,European Federation of Societies for ... 3rd of June 2008, in Timisoara, Romania. The ... excellent image quality,with comprehensive functions. High image quality ...
Cached Medicine News:Health News:AZO Answers the Burning Question: What's Up Down There? 2Health News:AZO Answers the Burning Question: What's Up Down There? 3Health News:AZO Answers the Burning Question: What's Up Down There? 4Health News:Kids' Energy Expenditure High in Active Video Games 2Health News:Novadaq Updates on OPTTX Data Reported at Euroretina 2Health News:Novadaq Updates on OPTTX Data Reported at Euroretina 3Health News:Novadaq Updates on OPTTX Data Reported at Euroretina 4Health News:Montana Center for Work Physiology and Exercise Metabolism Presents Firefighter Health Study 2Health News:ALOKA to Unveil a New Compact 'ProSound' Diagnostic Ultrasound System 2
(Date:7/10/2014)... SAN DIEGO , July 10, 2014  RESMED INC. ... report its fourth quarter and fiscal year ended June 30, ... York Stock Exchange market close. A press release with ResMed,s ... and the company will host a webcast to discuss operating ... scheduled to begin at 1:30 p.m. US Pacific Time and ...
(Date:7/10/2014)... 2014  Valeant Pharmaceuticals International, Inc. (NYSE: ... completed the sale to Galderma of all rights to ... by Valeant for $1.4 billion in cash, pursuant to ... completed its acquisition of Galderma. "We ... to a company that is firmly committed to the ...
(Date:7/10/2014)... July 10, 2014   LabStyle Innovations Corp ... today announced the appointment of Professor Richard ... its Board of Directors. Prof. Stone ... experience to LabStyle as an entrepreneur, venture capitalist ... corporate governance expert. He currently serves on the ...
Breaking Medicine Technology:ResMed To Announce Fourth Quarter And Fiscal Year-End 2014 Results 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 4
... 29, 2012 Specialty Silicone Fabricators (SSF), a ... device community, inaugurated its state-of-the-art 102,000 square-foot facility ... efficiency, the facility joins all Paso Robles departments, ... facilities in Tustin, Calif. and Elk Rapids, Mich. ...
... Health Specialty Solutions today launched PathWare™ Decision Transaction ... easier for payors and physicians to work together ... cost of caring for patients with complex diseases ... of Cardinal Health Specialty Solutions, flagship service offerings ...
Cached Medicine Technology:Specialty Silicone Fabricators Inaugurates New State-of-the-Art Facility in Paso Robles 2Cardinal Health Specialty Solutions Launches PathWare™ Decision Support Transaction Solutions 2Cardinal Health Specialty Solutions Launches PathWare™ Decision Support Transaction Solutions 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: