Navigation Links
New Prostate Cancer Drug May Hold Promise
Date:4/7/2009

Researchers apply for large-scale testing after 'very promising' early results,,

TUESDAY, April 7 (HealthDay News) -- A new drug with a radically different way of attacking prostate cancer has done well in an initial trial and is ready for larger-scale testing, researchers report.

One standard treatment for the malignancy is to inhibit the activity of androgens, male hormones such as testosterone that help drive tumor growth. Existing anti-androgens try to "shut down the factory" that produces the hormones, but the new drug blocks the receptors for those androgens on the tumor cells, said Dr. Howard I. Scher, chief of the genitourinary oncology service at Memorial Sloan-Kettering Cancer Center in New York City and co-author of a report to be published online by the journal Science.

"There is a lot of interest in the drug, because the preliminary results are very promising," Scher said.

The report in the journal describes the results of the treatment of 30 men with advanced prostate cancer that was not responding to conventional anti-androgen therapy. After treatment with the drug, there were "sustained declines" in blood levels of prostate specific antigen, a biomarker of tumor growth, in 13 of the 30, or 43 percent, which the report called a "promising" result.

The researchers now have data on 114 men given the drug, Scher said. "It showed not only declines in PSA but also regression of the tumor on scans and also that circulating tumor cell counts, another measure of treatment, converted from unfavorable to favorable in a considerable percentage of patients," he said.

Based on those results, Scher said, an application for a large-scale trial has been submitted to the U.S. Food and Drug Administration by Medivation Inc., a California-based biopharmaceutical company that has licensed the drug, now called MDV3100. The hope is that the trial will lead to FDA approval of the drug for clinica
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
2. First biomarker discovered that predicts prostate cancer outcome
3. Frequent Prostate Screens Fail to Improve Aggressive Cancer Diagnoses
4. New male sling procedure helps prostate cancer survivors who suffer from urinary incontinence
5. Us TOO Launches National SEA Blue Campaign for Prostate Cancer Awareness Month
6. Red wine compound shown to prevent prostate cancer
7. Barbershop Talks Cut Black Mens Prostate Cancer Risk
8. Generic prostate drug helps find high-risk cancers early
9. Finasteride unlikely to induce high grade prostate cancers
10. Shrinkage of prostate led to overestimation of cancer risk in trial
11. Prostate Cancer Awareness Week to Screen Thousands
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Prostate Cancer Drug May Hold Promise
(Date:9/1/2015)... ... September 01, 2015 , ... ... managed, stress created from everyday life changes can lead to very serious, life-altering ... support for coping with stress. Herbal supplement manufacturer MediHerb has coupled ...
(Date:9/1/2015)... , ... September 01, 2015 , ... ... to aid colleges and universities across the country in stemming sexual assaults on ... Campus Climate Collaborative (ARC3), a consortium of sexual assault researchers and student affairs ...
(Date:9/1/2015)... London, UK (PRWEB) , ... September 01, 2015 ... ... of a vacuum that creates negative pressure inside a wound to remove exudates, ... market for treatment devices (comprising portable devices, stand-alone devices, disposable devices, and canisters, ...
(Date:9/1/2015)... (PRWEB) , ... September 01, 2015 , ... The Jerry ... at The ACE Club and Green Valley Country Club in Lafayette Hill, PA. Over ... raised more than $13.5 million for programs and services designed to support patients and ...
(Date:9/1/2015)... ... September 01, 2015 , ... Royal River Natural Foods, a locally-owned independent natural ... women for 19 years and found that, among those who had a stroke, people ... report is part of the September 2015 issue of “Natural Insights for Well Being,” ...
Breaking Medicine News(10 mins):Health News:MediHerb Launches New Herbal Supplement to Help with the Challenges of Everyday Life 2Health News:MediHerb Launches New Herbal Supplement to Help with the Challenges of Everyday Life 3Health News:Georgia State, Partners Introduce Climate Survey to Aid in Preventing Campus Sexual Assaults 2Health News:World Negative Pressure Wound Therapy Market Assessed by GlobalData in In-demand Report Published at MarketPublishers.com 2Health News:World Negative Pressure Wound Therapy Market Assessed by GlobalData in In-demand Report Published at MarketPublishers.com 3Health News:The 26th Jerry Segal Classic Returns to Benefit Patients of Magee Rehabilitation Hospital 2Health News:The 26th Jerry Segal Classic Returns to Benefit Patients of Magee Rehabilitation Hospital 3Health News:New Study Finds Multivitamins Extend Life After Stroke, Retailer Reports 2
... national study, patients being treated for a rare ... University Hospital// (NSUH) and Long Island Jewish (LIJ) ... compound, coupled with standard chemotherapy treatments, significantly increases ... acute promyelocytic leukemia, or APL, and participated in ...
... the standard breast cancer therapy drug tamoxifen, to another one ... , Publishing their findings in the online version of The ... Institute, UK, and team, stood for changing treatments tracks to ... as it reduced deaths by 17 percent. ,Their ...
... encouragement to shut those eyes//. ,Scientists from the ... results that may make it worthwhile to have an afternoon ... Trichopoulos, lead researcher, looked at sleep patterns in Mediterranean countries ... Incidence or rates of heart diseases are low in ...
... Calcium and vitamin D supplementation, even over a short time ... bone) in female military// recruits, according to a study. ... of Defense, looked at 5,201 female U.S. Navy recruits during ... Great Lakes Naval Station near Chicago, Ill. ,The ...
... currently underway brings hope of dramatic advances in ... The review reveals that new approaches in breast ... and research on breast cancer vaccines may lead ... treating breast cancer patients. These new tools may ...
... Centre is planning to set up a 200-bed super ... centres with an initial investment of Rs.300 million. ... of the hospital, told IANS: "We are going to ... in Bangladesh with an aim to provide quality and ...
Cached Medicine News:Health News:Arsenic Compound Effective in Treating Rare Leukemia 2Health News:Arsenic Compound Effective in Treating Rare Leukemia 3Health News:New Drug Therapy for Breast Cancer Offers Hope 2Health News:Mid-day Naps Healthy for Your Heart 2Health News:Calcium, Vitamin D Supplements Reduce Stress Fractures in Military Recruits 2Health News:Emerging Research Heralds New Era of Breast Cancer Management 2Health News:Kolkata's Birla Hospital to Foray into Bangladesh 2
(Date:9/1/2015)... UT Southwestern Medical Center President Dr. Daniel K. ... Michael C. Burgess , M.D., and Joe ... st Century Cures Act, bipartisan legislation in support ... the United States Senate. UT ... department chairs, center directors, and leading researchers – joined ...
(Date:9/1/2015)... , Sept. 1, 2015   Alpha Imaging LLC , a ... Cleveland announced today that they have been awarded exclusive ... imaging systems in Michigan.   The new territory supplements Alpha Imaging,s existing ... including Ohio , Indiana , ... Maryland , West Virginia , ...
(Date:9/1/2015)... Taiwan,s GNT Biotech & Medicals ... Taipei on  August 25 th  to ... drug delivery technology that uses nano-scale gold as the ... a joint press conference held by its parent company ... latest edible gold-based food and beverage partners, together with ...
Breaking Medicine Technology:U.S. Rep. Michael C. Burgess, M.D., hosts roundtable at UT Southwestern to discuss pivotal 21st Century Cures Act and future of biomedical science 2U.S. Rep. Michael C. Burgess, M.D., hosts roundtable at UT Southwestern to discuss pivotal 21st Century Cures Act and future of biomedical science 3U.S. Rep. Michael C. Burgess, M.D., hosts roundtable at UT Southwestern to discuss pivotal 21st Century Cures Act and future of biomedical science 4U.S. Rep. Michael C. Burgess, M.D., hosts roundtable at UT Southwestern to discuss pivotal 21st Century Cures Act and future of biomedical science 5Alpha Imaging Expands Shimadzu Territory 2GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 2GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 3GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 4GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 5
... NEW DELHI, October 7 DBMS Consulting announced that ... Suite and Oracle E-Business Suite (EBS) for SIRO Clinpharm, ... OHSA offers fully,automated capabilities in management of clinical trial ... After this implementation, SIRO gains ...
... SAN DIEGO and BASKING RIDGE, N.J., Oct. 7 With ... said today from CTIA WIRELESS I.T. & Entertainment 2009® that ... for its Field Force Manager application that helps address the ... become more productive and efficient. , Designed specifically ...
Cached Medicine Technology:DBMS Consulting Successfully Completes Roll out of Oracle Health Sciences Applications (OHSA) Suite for SIRO Clinpharm 2DBMS Consulting Successfully Completes Roll out of Oracle Health Sciences Applications (OHSA) Suite for SIRO Clinpharm 3Verizon Wireless Offers Home Health Care Industry Custom Mobile Application To Be More Productive 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: