Navigation Links
New Prostate Cancer Biomarker Discovered

Finding also might apply in other types of cancer, researcher says

THURSDAY, June 18 (HealthDay News) -- A new marker for advanced prostate cancer and metastasis, or spread, of the disease has been identified by U.S. researchers.

Their analysis of prostate tissue from men with localized prostate cancer revealed that the men had significantly decreased levels of a stromal protein called caveolin-1. The researchers also found that the protein was not present in tumor tissue from men with metastatic prostate cancer.

Lower levels of caveolin-1 were associated with a high Gleason score, which is one of the most important predictors of poor clinical outcome among prostate cancer patients, according to the study, which appears online in advance of publication in the August print issue of Cell Cycle.

"We previously showed that the absence of stromal caveolin-1 is also associated with advanced tumor stage, early recurrence and metastasis of breast cancer," Dr. Michael Lisanti, a professor in the departments of cancer biology, medical oncology, and biochemistry and molecular biology at Jefferson Medical College at Thomas Jefferson University in Philadelphia, said in a university news release.

"Now we have identified [the protein's] similar prognostic value in prostate cancer," Lisanti added. "It is possible that this biomarker may be universal and could be widely applicable as a prognostic indicator for other cancer types as well."

More information

The American Cancer Society has more about prostate cancer.

-- Robert Preidt

SOURCE: Thomas Jefferson University, news release, June 16, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Organization Announces End Prostate Cancer Tour
2. Prostate Cancer Patient Receives First RapidArc Radiotherapy Treatment at Major Danish Hospital
3. Dad Offers Personal Father's Day Message on Importance of Prostate Cancer Screenings
4. Consumer Reports Best Buy Drug for Enlarged Prostate Could Save Consumers Nearly $3,000 a Year
5. New approach for treating recurrent prostate cancer on the horizon
6. Prostate Cancer Active Surveillance Protocol Clinical Trial Conducted by NorthShore University HealthSystem
7. Decision tool for prostate cancer patients helps men customize treatment in anxious time
8. Kimberly-Clark Teams Up With Sports Legends to Launch The Depend Campaign to End Prostate Cancer
9. Prostate cancer test improves prediction of disease course
10. Longer Hormone Treatment May Improve Prostate Cancer Outlook
11. Hormone therapy may confer more aggressive properties to prostate tumors
Post Your Comments:
Related Image:
New Prostate Cancer Biomarker Discovered
(Date:11/25/2015)... ... ... In an ongoing Clinical Study conducted by an independent physician, Andrew Gostine, ... evaluating the efficacy of its product and its disinfection protocol. This study is taking ... 2014 through October 2015 at a 360-bed, acute-care, academic medical center located in Chicago, ...
(Date:11/25/2015)... ... November 25, 2015 , ... In ... nation’s Periwinkle Pioneers, individuals and groups responsible for advancing care for pulmonary hypertension ... Pioneers, nominated by the public, will receive special recognition throughout 2016 as part ...
(Date:11/25/2015)... ... 25, 2015 , ... Many people know of the common symptoms of low ... dry skin. But many people who find their cholesterol levels and weight are creeping ... thyroid, especially if they don’t have any of the other symptoms. , Thyroid hormone ...
(Date:11/25/2015)... ... November 25, 2015 , ... Bunion ... in an early celebration of the early holiday shopping season. Starting Wednesday November ... (normally $33.95 ea). Black Friday promotional pricing is in addition to any automatic ...
(Date:11/24/2015)... ... ... New patients who wish to seek treatment for missing teeth can now ... Mississauga, ON practice. Dr. Williams has been providing dental service for over 34 years, ... teeth can lead to a variety of complications if they are not replaced quickly, ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... 2015  Thanks to a donor with a personal ... Center,s Sister Diane Grassilli Center for Women,s Health now ... San Francisco . Fred ... with a gift of $617,320 that allowed the Center ... Tomosynthesis and Whole Breast Ultrasound. Tomosynthesis, three-dimensional (3-D) mammography ...
(Date:11/24/2015)... Nov. 24, 2015 /PRNewswire/ - ESSA Pharma Inc. ("ESSA" ... announced today that the first patient has been enrolled ... a treatment for metastatic castration-resistant prostate cancer ("mCRPC"). ... --> the United States ... Phase 1/2 clinical trial, ESSA intends to demonstrate the ...
(Date:11/24/2015)... PUNE, India , November 24, 2015 ... new market research report "Spine Biologics Market by Product Type ... Type (Anterior Cervical Discectomy and Fusion, Posterior Lumbar Interbody Fusion), ... by MarketsandMarkets, the global market was valued at $1.90 Billion ... 2020, at a CAGR of 4.4% during the forecast period ...
Breaking Medicine Technology: