Navigation Links
New Piece of Alzheimer's Puzzle Identified
Date:12/2/2010

THURSDAY, Dec. 2 (HealthDay News) -- A problem in the lining of blood vessels may play a role in the development of Alzheimer's disease, according to a new study.

The condition, called endothelial dysfunction, involves a loss of nitric oxide in the endothelium, the layer of cells that line blood vessels. Nitric oxide is crucial to the widening of blood vessels (vasodilation) that improves blood flow and the delivery of oxygen and nutrients to tissues.

Previous research has linked endothelial dysfunction to cardiovascular disease.

In this new study, researchers from the Mayo Clinic in Rochester, Minn., found that endothelial dysfunction increases production of proteins that provide the raw material for the amyloid plaques seen in the brains of people with Alzheimer's disease.

The findings are published in the Dec. 2 online edition of the journal Circulation Research.

"On the cardiovascular side, we've known for some time that preservation of healthy endothelium is critical to prevent major cardiovascular events. Now it seems this may have important implications for cognitive impairment," senior author Dr. Zvonimir S. Katusic, a professor of anesthesiology and pharmacology at the Mayo Clinic, said in an American Heart Association news release.

He said the study may help explain how exercise benefits cardiovascular and brain health. Previous research has shown that exercise can delay or prevent cognitive impairment.

"There is a lot of literature showing that every time you exercise, you stimulate the endothelium to produce more nitric oxide. What we have identified in this paper may help explain the reported (cognitive) benefit of exercise," Katusic said.

More information

For more about exercise and brain health, visit the U.S. National Library of Medicine.

-- Robert Preidt

SOURCE: American Heart Association, news release, Dec. 2, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Secret to healing chronic wounds might lie in tiny pieces of silent RNA
2. Is it safe for endoscopic piecemeal mucosal resection in treating large sessile colorectal polyps?
3. Lung cancer patients are the centerpiece for Northwestern medicine quality of care study
4. A century-old puzzle comes together: Scientists ID potential protein trigger in lung disease sarcoidosis
5. Experts Optimistic About Solving Puzzle of Alzheimers
6. Tumor mechanism identified
7. Damaged protein identified as early diagnostic biomarker for Alzheimers disease in healthy adults
8. Meat Might Be Behind Many Unidentified Allergic Reactions
9. Predisposing factors for conversion of mild cognitive impairment to AD identified
10. Salmonella Tennessee Identified in a Processed Food Ingredient
11. Gene Mutations Identified for Charcot-Marie-Tooth Syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Piece of Alzheimer's Puzzle Identified
(Date:5/26/2016)... ... May 26, 2016 , ... There are nearly 14.5 million ... million cancer survivors worldwide. On Sunday, June 5, 2016, communities around the world will ... Survivors Day®. , National Cancer Survivors Day® is an annual worldwide Celebration of ...
(Date:5/26/2016)... , ... May 26, 2016 , ... In an effort to provide hair restoration information ... both Snapchat users and those who do not use the app. Dr. Mohebi, the founder ... page, Dr. Mohebi Live . , Dr. Mohebi says, “The positive response to ...
(Date:5/26/2016)... ... May 26, 2016 , ... North Cypress Medical ... at Blackhorse Golf Club in Cypress. With the help of community partners, the event ... empowers, and renews hope for wounded service members and their families through health, wellness, ...
(Date:5/26/2016)... ... May 26, 2016 , ... Power Systems, a leading developer ... Instructor Certification Course in Stoughton, Massachusetts. The course was led by Power Systems’ ... 8 hour interactive course to qualify participants as certified PowerWave trainers. , ...
(Date:5/26/2016)... ... ... The introduction of our professional athletes coincides with the company’s new campaign: “LOOK ... are proud to introduce Meghan Klingenberg, defender and World Champion with the US Women’s ... Los Angeles who was a second round selection in the 2012 NFL draft. We ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... -- Open Access Journal Focusing on ... Elsevier , a world-leading provider of scientific, technical ... launch of Clinical Neurophysiology Practice ... clinical practice issues in clinical neurophysiology. The journal will ... and didactic reviews. It is an official journal of ...
(Date:5/23/2016)... , May 23, 2016 ... Handling Equipment Market by Product (Wheelchair, Scooters, Medical ... (Bariatric Care, Critical Care, Wound), Accessories (Lifting, Transfer) ... to 2021", published by MarketsandMarkets, the patient handling ... Billion by 2021 at a CAGR of 10.5% ...
(Date:5/23/2016)... ALBANY, New York , May 23, 2016 /PRNewswire/ ... new market report titled, " Exocrine Pancreatic Insufficiency Market ... Forecast 2013 - 2023 ." According to the report, ... at a CAGR of 8.3% from 2015 to 2023 ... pancreatic insufficiency (EPI) is a condition characterized by the ...
Breaking Medicine Technology: