Navigation Links
New Piece of Alzheimer's Puzzle Identified
Date:12/2/2010

THURSDAY, Dec. 2 (HealthDay News) -- A problem in the lining of blood vessels may play a role in the development of Alzheimer's disease, according to a new study.

The condition, called endothelial dysfunction, involves a loss of nitric oxide in the endothelium, the layer of cells that line blood vessels. Nitric oxide is crucial to the widening of blood vessels (vasodilation) that improves blood flow and the delivery of oxygen and nutrients to tissues.

Previous research has linked endothelial dysfunction to cardiovascular disease.

In this new study, researchers from the Mayo Clinic in Rochester, Minn., found that endothelial dysfunction increases production of proteins that provide the raw material for the amyloid plaques seen in the brains of people with Alzheimer's disease.

The findings are published in the Dec. 2 online edition of the journal Circulation Research.

"On the cardiovascular side, we've known for some time that preservation of healthy endothelium is critical to prevent major cardiovascular events. Now it seems this may have important implications for cognitive impairment," senior author Dr. Zvonimir S. Katusic, a professor of anesthesiology and pharmacology at the Mayo Clinic, said in an American Heart Association news release.

He said the study may help explain how exercise benefits cardiovascular and brain health. Previous research has shown that exercise can delay or prevent cognitive impairment.

"There is a lot of literature showing that every time you exercise, you stimulate the endothelium to produce more nitric oxide. What we have identified in this paper may help explain the reported (cognitive) benefit of exercise," Katusic said.

More information

For more about exercise and brain health, visit the U.S. National Library of Medicine.

-- Robert Preidt

SOURCE: American Heart Association, news release, Dec. 2, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Secret to healing chronic wounds might lie in tiny pieces of silent RNA
2. Is it safe for endoscopic piecemeal mucosal resection in treating large sessile colorectal polyps?
3. Lung cancer patients are the centerpiece for Northwestern medicine quality of care study
4. A century-old puzzle comes together: Scientists ID potential protein trigger in lung disease sarcoidosis
5. Experts Optimistic About Solving Puzzle of Alzheimers
6. Tumor mechanism identified
7. Damaged protein identified as early diagnostic biomarker for Alzheimers disease in healthy adults
8. Meat Might Be Behind Many Unidentified Allergic Reactions
9. Predisposing factors for conversion of mild cognitive impairment to AD identified
10. Salmonella Tennessee Identified in a Processed Food Ingredient
11. Gene Mutations Identified for Charcot-Marie-Tooth Syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Piece of Alzheimer's Puzzle Identified
(Date:2/9/2016)... ... February 09, 2016 , ... Shark Finds and Kevin Harrington, and the Product Managers ... , GRIP-DRY is a newly patented product that has solved some of the basic problems ... and early morning dew or right after a rain shower, might understand the struggle of ...
(Date:2/8/2016)... ... February 08, 2016 , ... CURE Media Group , the nation’s ... Multiple Myeloma Heroes Awards event , which will annually honor individuals making heroic ... with MM. The MM Heroes Awards nomination process is officially open through ...
(Date:2/8/2016)... ... February 08, 2016 , ... Brenntag Specialties, Inc.(BSI) , ... Food & Beverage and Dietary Supplement market segments across the ... USA geographies east of the Rocky Mountains since 2012. Consistent performance in ...
(Date:2/8/2016)... ... 08, 2016 , ... Stephanie Hebert Insurance Agency, serving families ... new charity campaign. As part of their ongoing community involvement program, funds are ... that children deserve a voice, and in the spirit of neighbors helping neighbors ...
(Date:2/8/2016)... Angeles, CA (PRWEB) , ... February 08, 2016 , ... A man who has struggled ... of Freedom Laser Therapy , was determined to find solutions to his problems – ... of Inventors Digest is ready to introduce his breakthrough inventions to the world ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... , Feb. 8, 2016 CBG ... the PW Series Solvent Recycling Systems, specifically designed ... full integration with new and existing vapor degreasers, ... produces consistently-fresh solvent through continuous recycling and recovers ... --> --> Precision parts ...
(Date:2/8/2016)... 2016 --> ... "Ablation Technologies Market by Product (Radiofrequency, Ultrasound, Irreversible Electroporation, ... Surgery, Ophthalmology, Gynecology) - Global Forecasts to 2020", published ... the forecast period of 2015 to 2020. The market ... CAGR of 10.5% from 2015 to 2020. ...
(Date:2/8/2016)... EAST NORRITON, Pa. , Feb. 8, 2016 ... acquisition of November Research Group (NRG),s pharmacovigilance ... of pharmacovigilance system-related consulting services and an Oracle ... regulatory compliance services to Life Sciences companies. ... acquisition strengthens and expands HighPoint,s life sciences capabilities ...
Breaking Medicine Technology: