Navigation Links
New Piece of Alzheimer's Puzzle Identified
Date:12/2/2010

THURSDAY, Dec. 2 (HealthDay News) -- A problem in the lining of blood vessels may play a role in the development of Alzheimer's disease, according to a new study.

The condition, called endothelial dysfunction, involves a loss of nitric oxide in the endothelium, the layer of cells that line blood vessels. Nitric oxide is crucial to the widening of blood vessels (vasodilation) that improves blood flow and the delivery of oxygen and nutrients to tissues.

Previous research has linked endothelial dysfunction to cardiovascular disease.

In this new study, researchers from the Mayo Clinic in Rochester, Minn., found that endothelial dysfunction increases production of proteins that provide the raw material for the amyloid plaques seen in the brains of people with Alzheimer's disease.

The findings are published in the Dec. 2 online edition of the journal Circulation Research.

"On the cardiovascular side, we've known for some time that preservation of healthy endothelium is critical to prevent major cardiovascular events. Now it seems this may have important implications for cognitive impairment," senior author Dr. Zvonimir S. Katusic, a professor of anesthesiology and pharmacology at the Mayo Clinic, said in an American Heart Association news release.

He said the study may help explain how exercise benefits cardiovascular and brain health. Previous research has shown that exercise can delay or prevent cognitive impairment.

"There is a lot of literature showing that every time you exercise, you stimulate the endothelium to produce more nitric oxide. What we have identified in this paper may help explain the reported (cognitive) benefit of exercise," Katusic said.

More information

For more about exercise and brain health, visit the U.S. National Library of Medicine.

-- Robert Preidt

SOURCE: American Heart Association, news release, Dec. 2, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Secret to healing chronic wounds might lie in tiny pieces of silent RNA
2. Is it safe for endoscopic piecemeal mucosal resection in treating large sessile colorectal polyps?
3. Lung cancer patients are the centerpiece for Northwestern medicine quality of care study
4. A century-old puzzle comes together: Scientists ID potential protein trigger in lung disease sarcoidosis
5. Experts Optimistic About Solving Puzzle of Alzheimers
6. Tumor mechanism identified
7. Damaged protein identified as early diagnostic biomarker for Alzheimers disease in healthy adults
8. Meat Might Be Behind Many Unidentified Allergic Reactions
9. Predisposing factors for conversion of mild cognitive impairment to AD identified
10. Salmonella Tennessee Identified in a Processed Food Ingredient
11. Gene Mutations Identified for Charcot-Marie-Tooth Syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Piece of Alzheimer's Puzzle Identified
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual ... in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon ... fun run is geared towards children of all ages; it is a non-competitive, non-timed ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... will be giving viewers the lowdown on sciatica in a new episode of ... that focuses on current events and innovation and investigates each subject in-depth with ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the ... save lost souls in the Philippines. “The Journey: From the Mountains to the Mission ... of the Bible. She has taught all ages and currently teaches a class of ...
(Date:10/12/2017)... ... October 12, 2017 , ... First ... compliance program management, will showcase a range of technology and learning solutions at ... (NCAL) Convention and Expo to be held October 14–18, 2017 at the Mandalay ...
(Date:10/12/2017)... Orleans, LA (PRWEB) , ... October 12, 2017 , ... ... centers in the U.S., announced today its plans to open a flagship location in ... will occupy the former Rooms To Go store next to Office Depot in the ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... NEW YORK , Sept. 27, 2017  DarioHealth Corp. ... big data solutions, today announced that its MyDario product is expected to ... TV listings for when The Dr. Oz Show airs in your area: ... The nine-time Emmy award-winning, ... ...
(Date:9/23/2017)... -- Janssen Biotech, Inc. (Janssen) announced today that it ... Food and Drug Administration (FDA) for the Biologics License ... of moderately to severely active rheumatoid arthritis (RA). The ... to further evaluate the safety of sirukumab in the ... "We are disappointed by ...
(Date:9/19/2017)... medical device company developing a non-invasive, robotically assisted, platform therapy that uses pulsed sound energy ... ... Jim Bertolina, PhD ... Tom Tefft ... executive Josh Stopek , PhD, who has led R&D and business development teams at ...
Breaking Medicine Technology: