Navigation Links
New Piece of Alzheimer's Puzzle Identified

THURSDAY, Dec. 2 (HealthDay News) -- A problem in the lining of blood vessels may play a role in the development of Alzheimer's disease, according to a new study.

The condition, called endothelial dysfunction, involves a loss of nitric oxide in the endothelium, the layer of cells that line blood vessels. Nitric oxide is crucial to the widening of blood vessels (vasodilation) that improves blood flow and the delivery of oxygen and nutrients to tissues.

Previous research has linked endothelial dysfunction to cardiovascular disease.

In this new study, researchers from the Mayo Clinic in Rochester, Minn., found that endothelial dysfunction increases production of proteins that provide the raw material for the amyloid plaques seen in the brains of people with Alzheimer's disease.

The findings are published in the Dec. 2 online edition of the journal Circulation Research.

"On the cardiovascular side, we've known for some time that preservation of healthy endothelium is critical to prevent major cardiovascular events. Now it seems this may have important implications for cognitive impairment," senior author Dr. Zvonimir S. Katusic, a professor of anesthesiology and pharmacology at the Mayo Clinic, said in an American Heart Association news release.

He said the study may help explain how exercise benefits cardiovascular and brain health. Previous research has shown that exercise can delay or prevent cognitive impairment.

"There is a lot of literature showing that every time you exercise, you stimulate the endothelium to produce more nitric oxide. What we have identified in this paper may help explain the reported (cognitive) benefit of exercise," Katusic said.

More information

For more about exercise and brain health, visit the U.S. National Library of Medicine.

-- Robert Preidt

SOURCE: American Heart Association, news release, Dec. 2, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Secret to healing chronic wounds might lie in tiny pieces of silent RNA
2. Is it safe for endoscopic piecemeal mucosal resection in treating large sessile colorectal polyps?
3. Lung cancer patients are the centerpiece for Northwestern medicine quality of care study
4. A century-old puzzle comes together: Scientists ID potential protein trigger in lung disease sarcoidosis
5. Experts Optimistic About Solving Puzzle of Alzheimers
6. Tumor mechanism identified
7. Damaged protein identified as early diagnostic biomarker for Alzheimers disease in healthy adults
8. Meat Might Be Behind Many Unidentified Allergic Reactions
9. Predisposing factors for conversion of mild cognitive impairment to AD identified
10. Salmonella Tennessee Identified in a Processed Food Ingredient
11. Gene Mutations Identified for Charcot-Marie-Tooth Syndrome
Post Your Comments:
Related Image:
New Piece of Alzheimer's Puzzle Identified
(Date:11/30/2015)... ... 30, 2015 , ... Brenntag Specialties, Inc. (BSI) has been ... Nutraceutical Specialties products into oral solid dosage in the over the counter vitamin ... pleased to announce our expanded distribution agreement with ASI.” said Steve Brauer, President ...
(Date:11/30/2015)... Santa Rosa, Calif. (PRWEB) , ... November 30, ... ... Health Management and Analytics for the last 15 years, announced today that Michigan-based ... , A provider of care for over 45 years, FHC was awarded the ...
(Date:11/30/2015)... ... November 30, 2015 , ... An inventor from Charlottesville, Va., ... womb. "My last baby had high blood pressure due to loud noises," she said, ... their babies from noise pollution as well as radio waves and microwaves." , The ...
(Date:11/30/2015)... ... November 30, 2015 , ... In an interview with Andy Mitchell ... top ophthalmologist on Long Island’s east end. During the broadcast, entitled “Eyes: the Window ... treatment of glaucoma and cataracts, and how a visit with his grandmother to her ...
(Date:11/30/2015)... ... 30, 2015 , ... Since its inception, Seniors Guide has ... assisted living and all other retirement options. Support for issues surrounding the senior ... a top priority. , So it’s no surprise that every November, Seniors ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... India , November 30, 2015 ... --> adds ... trends for 2010 - 2015 with ... for a range of deal types, ... and strategic alliances. ...
(Date:11/30/2015)... 30, 2015  PTS Diagnostics, the U.S.-based manufacturer of ... analyzers, A1CNow ® systems, and PTS Detect™ cotinine ... patents that will propel the company into the mHealth ... Europe . The technology is a system ... on smartphones and tablets, and uses test strip technology ...
(Date:11/30/2015)... iCAD, Inc. (Nasdaq: ICAD ) ... solutions for advanced image analysis and workflow tools ... Radiological Society of North American (RSNA) 2015 Annual ... November 29 to December 4, 2015. The company ... automated breast density assessment solution, PowerLook® Advanced Mammography ...
Breaking Medicine Technology: