Navigation Links
New Method to Reveal Alzheimer's Marker Shows Promise
Date:4/17/2012

TUESDAY, April 17 (HealthDay News) -- New research adds to the growing pile of scientific strategies aimed at revealing beta-amyloid (protein) plaques, the brain-clogging fragments that have been associated with Alzheimer's disease.

In a study funded by Bayer Healthcare Berlin, researchers report that they were able to use a drug and PET scans to successfully detect plaques in the brains of patients whose Alzheimer's was confirmed after death.

More than 200 patients near death -- including some with apparent Alzheimer's disease -- underwent the PET scans. They received doses of the drug florbetaben, which was used as a "tracer" to allow the PET scans to detect the plaques.

Thirty-one patients died and had autopsies to confirm that they had Alzheimer's disease. The researchers determined that one way of interpreting the PET scan results correctly pinpointed Alzheimer's disease 100 percent of the time and correctly ruled it out 92 percent of the time.

"These results confirm that florbetaben is able to detect beta-amyloid plaques in the brain during life with great accuracy and is a suitable biomarker," study author Dr. Marwan Sabbagh, director of Banner Sun Health Research Institute in Sun City, Ariz., said in an American Academy of Neurology news release.

"This is an easy, noninvasive way to assist an Alzheimer's diagnosis at an early stage. Also exciting is the possibility of using florbetaben as a tool in future therapeutic clinical research studies where therapy goals focus on reducing levels of beta-amyloid in the brain," Sabbagh added.

Dr. William Jagust, a professor of neuroscience at the University of California, Berkeley's Helen Wills Neuroscience Institute, said several companies are developing ways to detect beta-amyloid plaques. "It's a very important development in our field," he said. "The big practical question is how much is this going to cost -- it may cost $2,000 or more to get a scan -- and whether it is worth it considering what we can do for such patients."

There's no cure for Alzheimer's and no way to reverse it, although drugs are available to treat symptoms. Still, Jagust said, detecting beta-amyloids may be helpful as a way to determine whether experimental drugs actually work.

The study is slated for presentation at the American Academy of Neurology's annual meeting, which starts April 21 in New Orleans.

The data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

For more about Alzheimer's disease, try the U.S. National Library of Medicine.

--Randy Dotinga

SOURCES: William Jagust, M.D., professor, neuroscience, Helen Wills Neuroscience Institute, University of California, Berkeley; presentation, American Academy of Neurology annual meeting (April 21-28, 2012), New Orleans; AAN news release


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Nonsurgical Method to Measure Brain Pressure Shows Promise
2. Lung cancers detected by CT screening grow as fast as those found with traditional methods
3. 1 more player on the pitch thanks to a new training method
4. Natural method for clearing cellular debris provides new targets for lupus treatment
5. Wayne State research reveals improved method for paramedics to stop prolonged seizures
6. New method makes it easier to treat prostate and pancreatic cancer
7. Study finds pregnant women with prior cesarean choose the delivery method preferred by their doctor
8. New Scoring Method May Help Predict Stroke Outcome
9. A new screening method for prostate cancer
10. Researchers discover method to unravel malarias genetic secrets
11. Experts urge BMI method for calculating weight in kids with eating disorders
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Method to Reveal Alzheimer's Marker Shows Promise
(Date:5/26/2017)... ... , ... Amir Qureshi, MD is the first physician in Arkansas to implant ... The Nuvectra™ Algovita SCS System has been FDA approved as a treatment option for ... to introduce the most powerful SCS system and the only stretchable lead on the ...
(Date:5/26/2017)... ... May 26, 2017 , ... A new analysis of community health data ... are located in the Midwest. With the average cost of healthcare rising and the ... with both the quality and affordability of where they live. An annual 2017 report ...
(Date:5/26/2017)... ... May 26, 2017 , ... via seating is proud to ... task chair specifically designed for clinical areas. Genie Copper Mesh is a crossover ... Cupron® to provide customers with a game changing chair that is affordably priced,” ...
(Date:5/26/2017)... ... ... After raising nearly $30,000 on Kickstarter , about three-times its original campaign ... crowdfunding price on Indiegogo . , “Along with creating an anti-stress gadget to ... fidget toy to the market that was made of superior quality and wouldn’t break ...
(Date:5/26/2017)... (PRWEB) , ... May 26, 2017 , ... Silver Birch ... community, which is located on more than four acres of land at 5620 Sohl ... , The 103,000 square-foot building includes 125 studio and one-bedroom apartments. Each of ...
Breaking Medicine News(10 mins):
(Date:5/6/2017)... , May 5, 2017   Provista , a proven ... than 200,000 customers, today announced Jim Cunniff as ... of executive and business experience to Provista, including most recently ... in California . He assumed his new ... is a great fit for Provista," says Jody Hatcher ...
(Date:5/4/2017)... Tenn. , May 4, 2017  A ... Infection Control, Ultraviolet-C light as a ... Tru-D SmartUVC,s ability to reduce bioburden on anesthesia ... bioburden reduction on high-touch, complex medical equipment surfaces ... surgical infections. "This study further validates ...
(Date:5/4/2017)... May 4, 2017  A new tight-tolerance microextrusion ... other highly-engineered materials, is being launched by Natvar, ... been developed in recent years to service a ... surgical applications. More expensive materials such as glass ... tubing due to their ability to consistently hold ...
Breaking Medicine Technology: