Navigation Links
New Method to Reveal Alzheimer's Marker Shows Promise
Date:4/17/2012

TUESDAY, April 17 (HealthDay News) -- New research adds to the growing pile of scientific strategies aimed at revealing beta-amyloid (protein) plaques, the brain-clogging fragments that have been associated with Alzheimer's disease.

In a study funded by Bayer Healthcare Berlin, researchers report that they were able to use a drug and PET scans to successfully detect plaques in the brains of patients whose Alzheimer's was confirmed after death.

More than 200 patients near death -- including some with apparent Alzheimer's disease -- underwent the PET scans. They received doses of the drug florbetaben, which was used as a "tracer" to allow the PET scans to detect the plaques.

Thirty-one patients died and had autopsies to confirm that they had Alzheimer's disease. The researchers determined that one way of interpreting the PET scan results correctly pinpointed Alzheimer's disease 100 percent of the time and correctly ruled it out 92 percent of the time.

"These results confirm that florbetaben is able to detect beta-amyloid plaques in the brain during life with great accuracy and is a suitable biomarker," study author Dr. Marwan Sabbagh, director of Banner Sun Health Research Institute in Sun City, Ariz., said in an American Academy of Neurology news release.

"This is an easy, noninvasive way to assist an Alzheimer's diagnosis at an early stage. Also exciting is the possibility of using florbetaben as a tool in future therapeutic clinical research studies where therapy goals focus on reducing levels of beta-amyloid in the brain," Sabbagh added.

Dr. William Jagust, a professor of neuroscience at the University of California, Berkeley's Helen Wills Neuroscience Institute, said several companies are developing ways to detect beta-amyloid plaques. "It's a very important development in our field," he said. "The big practical question is how much is this going to cost -- it may cost $2,000 or more to get a scan -- and whether it is worth it considering what we can do for such patients."

There's no cure for Alzheimer's and no way to reverse it, although drugs are available to treat symptoms. Still, Jagust said, detecting beta-amyloids may be helpful as a way to determine whether experimental drugs actually work.

The study is slated for presentation at the American Academy of Neurology's annual meeting, which starts April 21 in New Orleans.

The data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

For more about Alzheimer's disease, try the U.S. National Library of Medicine.

--Randy Dotinga

SOURCES: William Jagust, M.D., professor, neuroscience, Helen Wills Neuroscience Institute, University of California, Berkeley; presentation, American Academy of Neurology annual meeting (April 21-28, 2012), New Orleans; AAN news release


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Nonsurgical Method to Measure Brain Pressure Shows Promise
2. Lung cancers detected by CT screening grow as fast as those found with traditional methods
3. 1 more player on the pitch thanks to a new training method
4. Natural method for clearing cellular debris provides new targets for lupus treatment
5. Wayne State research reveals improved method for paramedics to stop prolonged seizures
6. New method makes it easier to treat prostate and pancreatic cancer
7. Study finds pregnant women with prior cesarean choose the delivery method preferred by their doctor
8. New Scoring Method May Help Predict Stroke Outcome
9. A new screening method for prostate cancer
10. Researchers discover method to unravel malarias genetic secrets
11. Experts urge BMI method for calculating weight in kids with eating disorders
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Method to Reveal Alzheimer's Marker Shows Promise
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... Pixel Film ... Pro X. , "Film editors can give their videos a whole new perspective by ... Austin - CEO of Pixel Film Studios. , ProSlice Levels contains over 30 ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the ... AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in ... topics including advance care planning, healthcare costs and patient and family engagement. , ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... First ... United States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell ... facility Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, whether ... latter, setting the bar too high can result in disappointment, perhaps even self-loathing. However, ... their goal. , Research from PsychTests.com reveals that behind the tendency ...
(Date:6/24/2016)... PASADENA, CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. ... he would lash out at his family verbally and physically. , “When something upset him, ... table, he would use it. He would throw rocks at my other children and say ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016  Arkis BioSciences, a leading innovator in ... durable cerebrospinal fluid treatments, today announced it has ... is led by Innova Memphis, followed by Angel ... investors.  Arkis, new financing will accelerate the commercialization ... release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Dialysis Devices Global Market - Forecast to 2022" report ... is the treatment method for the patients with kidney failure, ... and excess fluid from the patient,s blood and thus the ... sodium, potassium and chloride in balance. Increasing ...
(Date:6/23/2016)... Research and Markets has announced ... Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality ... - Global Forecast to 2021" report to their ... global pharmaceutical excipients market is projected to reach USD ... in the forecast period 2016 to 2021. ...
Breaking Medicine Technology: