Navigation Links
New Method to Reveal Alzheimer's Marker Shows Promise
Date:4/17/2012

TUESDAY, April 17 (HealthDay News) -- New research adds to the growing pile of scientific strategies aimed at revealing beta-amyloid (protein) plaques, the brain-clogging fragments that have been associated with Alzheimer's disease.

In a study funded by Bayer Healthcare Berlin, researchers report that they were able to use a drug and PET scans to successfully detect plaques in the brains of patients whose Alzheimer's was confirmed after death.

More than 200 patients near death -- including some with apparent Alzheimer's disease -- underwent the PET scans. They received doses of the drug florbetaben, which was used as a "tracer" to allow the PET scans to detect the plaques.

Thirty-one patients died and had autopsies to confirm that they had Alzheimer's disease. The researchers determined that one way of interpreting the PET scan results correctly pinpointed Alzheimer's disease 100 percent of the time and correctly ruled it out 92 percent of the time.

"These results confirm that florbetaben is able to detect beta-amyloid plaques in the brain during life with great accuracy and is a suitable biomarker," study author Dr. Marwan Sabbagh, director of Banner Sun Health Research Institute in Sun City, Ariz., said in an American Academy of Neurology news release.

"This is an easy, noninvasive way to assist an Alzheimer's diagnosis at an early stage. Also exciting is the possibility of using florbetaben as a tool in future therapeutic clinical research studies where therapy goals focus on reducing levels of beta-amyloid in the brain," Sabbagh added.

Dr. William Jagust, a professor of neuroscience at the University of California, Berkeley's Helen Wills Neuroscience Institute, said several companies are developing ways to detect beta-amyloid plaques. "It's a very important development in our field," he said. "The big practical question is how much is this going to cost -- it may cost $2,000 or more to get a scan -- and whether it is worth it considering what we can do for such patients."

There's no cure for Alzheimer's and no way to reverse it, although drugs are available to treat symptoms. Still, Jagust said, detecting beta-amyloids may be helpful as a way to determine whether experimental drugs actually work.

The study is slated for presentation at the American Academy of Neurology's annual meeting, which starts April 21 in New Orleans.

The data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

For more about Alzheimer's disease, try the U.S. National Library of Medicine.

--Randy Dotinga

SOURCES: William Jagust, M.D., professor, neuroscience, Helen Wills Neuroscience Institute, University of California, Berkeley; presentation, American Academy of Neurology annual meeting (April 21-28, 2012), New Orleans; AAN news release


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Nonsurgical Method to Measure Brain Pressure Shows Promise
2. Lung cancers detected by CT screening grow as fast as those found with traditional methods
3. 1 more player on the pitch thanks to a new training method
4. Natural method for clearing cellular debris provides new targets for lupus treatment
5. Wayne State research reveals improved method for paramedics to stop prolonged seizures
6. New method makes it easier to treat prostate and pancreatic cancer
7. Study finds pregnant women with prior cesarean choose the delivery method preferred by their doctor
8. New Scoring Method May Help Predict Stroke Outcome
9. A new screening method for prostate cancer
10. Researchers discover method to unravel malarias genetic secrets
11. Experts urge BMI method for calculating weight in kids with eating disorders
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Method to Reveal Alzheimer's Marker Shows Promise
(Date:2/10/2016)... ... 2016 , ... United Benefit Advisors (UBA), the nation’s leading ... its growing list of Partner Firms. S.S. Nesbitt is headquartered in Birmingham, ... and in between. , Harnessing the experience and insights of the agency’s team ...
(Date:2/10/2016)... ... 2016 , ... Pediatric therapists are challenged to use evidence ... the Goal Attainment Scale (GAS) captures 20% more change in outcomes than other ... the Goal Attainment Scale, Education Resources Inc. is offering a course focused on ...
(Date:2/10/2016)... MA (PRWEB) , ... February 10, 2016 , ... ... their revolutionary, biocompatible columns and accessories. These PEEK-lined stainless steel (PLS) columns combine ... provide a solution that ensures the integrity of biological samples while operating at ...
(Date:2/10/2016)... ... February 10, 2016 , ... Anxiety of older Americans ... start of Medicare Part D a decade ago, according to The Senior Citizens ... adults on how they are coping with rapidly rising costs. “The implications are ...
(Date:2/10/2016)... ... February 09, 2016 , ... Traumatic Brian Injury is ... may be one of many possible sources: sports, car accidents, falls, work accidents, ... Mastering Rehab Solutions for the Complexities of Concussions is designed for ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... , February 10, 2016 Puerto Rico ... Puerto Rico Healthcare and Life Sciences Report 2016 ... page Puerto Rico Healthcare and Life Sciences Report 2016 ... into the fifth largest territory in the world for pharma ... device and diagnostics manufacturing, and more universities per square mile ...
(Date:2/10/2016)... , Feb. 10, 2016 Convergence ... confluence of various technologies that results in ... unavailable. These opportunities create a cyclical system ... turn, drives the development of new technologies. ... characterized by technology convergences, which are constantly ...
(Date:2/10/2016)... PRINCETON, New Jersey and OR AKIVA, ... Regentis Biomaterials Ltd., a leader ... of its Series D investment round on February 5, ... Haisco Pharmaceutical Group ("Haisco"), a leading Chinese pharmaceutical ... Medica Partners, SCP Vitalife Partners, Generali Financial Holdings and ...
Breaking Medicine Technology: