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New Mesothelioma Treatment Shows Promise
Date:3/22/2010

Non-toxic vaccine clinical trial, funded by the Mesothelioma Applied Research Foundation, publishes successful results for mesothelioma treatment.

(PRWEB) March 22, 2010 -- A new dendritic cell-based immunotherapy has been demonstrated in clinical trial to be well-tolerated and capable of inducing an immunological response against mesothelioma cells in patients.

In the study, funded by the Mesothelioma Applied Research Foundation and just published in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine, researchers administered three vaccinations of clinical-grade autologous dendritic cells to ten pleural mesothelioma patients. Distinct immunological responses, with moderate fever as the only side-effect, and with no evidence of autoimmunity or severe toxicities, mark an important milestone in mesothelioma research.

“For the past several years, aggressive chemotherapy has been utilized as an often effective, but difficult-to-tolerate, drug regimen for mesothelioma treatment. The prospect of adding to our arsenal other effective, but less toxic and better-tolerated, treatments will broaden greatly our ability to treat patients,” says Mary Hesdorffer, NP, Medical Liaison for the Mesothelioma Applied Research Foundation.

Joachim G. Aerts, a co-author of the research study and pulmonary physician at Erasmus Medical
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