Navigation Links
New Melanoma Drug May Extend Survival
Date:6/25/2012

MONDAY, June 25 (HealthDay News) -- New research suggests that a new drug does a better job of combating advanced skin cancer in melanoma patients than chemotherapy.

However, patients typically still got worse after only a few months on the drug.

The drug, called dabrafenib, blocks a signaling protein and is used to treat melanomas with a specific genetic mutation. About half of melanoma patients have this mutation.

In a phase 3 trial funded by the drug's maker, GlaxoSmithKline, an international group of researchers led by Dr. Axel Hauschild of the Schleswig-Holstein University Hospital in Kiel, Germany, gave dabrafenib or the most common existing treatment, dacarbazine (DTIC-Dome), to 250 patients with spreading or inoperable melanoma. About half responded partially (47 percent) or fully (3 percent) to dabrafenib; the response rate among the dacarbazine group was just 6 percent.

Those who took the new drug survived for an average of 5.1 months without getting worse; 2.7 percent of those treated with the existing drug did the same.

The study authors report that the new drug had few side effects, and those related to the skin appeared to be less severe than in patients on a similar drug called vemurafenib (Zelboraf). That drug is now available in the United States.

It's not clear if the drug will affect overall survival rates. "This trial is good news for our patients with metastatic melanoma. Competition in the field is appreciated since it accelerates new clinical trials, particularly in the combinational setting," Hauschild said in a news release from The Lancet, which published the study online June 25.

"This trial is a major step forward in the run for an improvement of the survival for this disease, which was thought to be untreatable for decades," he added.

Dr. Vernon K. Sondak, chair of the department of cutaneous oncology at the Moffitt Cancer Center in Tampa, said treatmen
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Surgery Rates Rising for Non-Melanoma Skin Cancer: Study
2. Moffitt Cancer Center researchers working at frontiers of melanoma research
3. Women More Likely to Survive Melanoma Than Men: Study
4. Scientists Map Melanomas Genome
5. Two-Drug Combo May Be Safe for Melanoma Treatment
6. Melanoma a Big Threat to Older Men
7. Fish shed light on human melanoma
8. LA BioMed investigators, Drs. Kevin Bruhn and Noah Craft, develop novel treatment for melanoma
9. Healthy Behaviors Extend Life After Cancer, Experts Say
10. Exercise and a healthy diet of fruits and vegetables extends life expectancy in women in their 70s
11. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Melanoma Drug May Extend Survival
(Date:10/22/2014)... On October 22, CBS will air ... diseases both fictional and real. The Charles E ... committed to advocacy and philanthropy in the battle against ... opportunity to impart truth and clarity about this misunderstood ... many misconceptions about Morgellons Disease (MD) and ...
(Date:10/22/2014)... Springfield, Va. (PRWEB) October 22, 2014 For ... way to make money; it’s an extension of her life’s ... her latest venture as the owner of FirstLight HomeCare, make ... , “It’s important to me that my work makes a ... always harbored an entrepreneurial spirit, so after much research, I ...
(Date:10/22/2014)... Shriners Hospitals for Children® and UK HealthCare have ... of Shriners Hospitals for Children - Lexington from 1900 ... of Kentucky Albert B. Chandler Hospital. The new facility ... operated by Shriners Hospitals for Children, and designed to ... families well into the future. , “The quality care ...
(Date:10/22/2014)... 22, 2014 With the Affordable Care Act ... by the American Institutes for Research (AIR) finds that three ... use health insurance, but 42 percent say they are not ... before signing up for coverage. , The AIR survey found ... percent able to calculate correctly how much they owe for ...
(Date:10/22/2014)... Healthcare professionals who are looking ... at home or on-the-go via laptops, tablets or ... new, premium Seminar-on-Demand CE courses. The new courses ... 2,000 hours of CE course offerings, allowing ... With such a diverse library, there’s something for ...
Breaking Medicine News(10 mins):Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 2Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 3Health News:Dr. Iris Hunter to Host Grand Opening of FirstLight HomeCare Tomorrow 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 3Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 2Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 3Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 4Health News:Top Provider of Continuing Education at Home Releases 20 New Online Courses 2
... FRIDAY, May 27 (HealthDay News) -- Youngsters who do not ... to be overweight, a new study has found. ... in body mass index (BMI) and a significant drop in ... also found lower BMIs resulted from differences in fat mass ...
... The American Society for Radiation Oncology (ASTRO) Annual ... with 2011 Hermes Creative Awards from the Association of ... year in a row that ASTRO has received Hermes ... for creative professionals involved in the concept, writing and ...
... -- People living in an area of the southeastern ... at greater risk for cognitive decline, or reduced brain ... suggests. The Stroke Belt states -- known to ... rest of the country -- include Alabama, Arkansas, Georgia, ...
... 26, 2011) Dr. Joseph P. Kerwin is a recipient of ... "influential contributions to space biomedical research and space medicine." Kerwin, a ... first U.S. medical doctor to travel in space when the Skylab ... member of the first crew to live aboard the Skylab space ...
... 2011Folic acid supplements given to pregnant and breast-feeding rats ... by 64 per cent, a new study has found. ... gastroenterologist at St. Michael,s Hospital, adds to the growing ... pregnancy and lactation can increase or decrease the development ...
... (HealthDay News) -- The ability to read minds has long ... fiction, but new research suggests it could one day become ... say they have found a way to identify the type ... "It,s a bit like unlocking a scrambled television channel. Before, ...
Cached Medicine News:Health News:More Sleep May Cut Kids' Risk of Obesity 2Health News:U.S. Southeast 'Stroke Belt' Also Shows Higher Rates of Cognitive Decline 2Health News:America's first doctor in space honored by Baylor College of Medicine 2Health News:Folic acid given to mother rats protects offspring from colon cancer 2Health News:Scientists Appear One Step Closer to Reading Minds 2
(Date:10/22/2014)... , Oct. 22, 2014 Moms are ... health trackers for themselves and their kids, according to ... Report: Health & Fitness Go Mobile for Moms, the ... Series. BabyCenter, the number 1 pregnancy and parenting web ... that 55 percent of moms surveyed say they can,t ...
(Date:10/22/2014)...  With a vision to ensure safety and ... Pharmaceutical and Biotech manufacturer selects and implements the ... to protect their animal health brand.  ... Photo - http://photos.prnewswire.com/prnh/20141021/153439 ... by the Xyntek and Antares solution is an ...
(Date:10/22/2014)... 2014 Influenza will affect as many as 200,000 ... the United States as high as 49,000 people.  ... is from person to person in respiratory droplets of coughs ... of death, but kills much fewer people each year than ... human fluids including sweat, saliva, blood and other bodily fluids. ...
Breaking Medicine Technology:BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 2BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 3BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 4Xyntek and Antares Serialization Solution Protects Pets Too! 2WholeHealth Products is proud to be releasing its Influenza A and B combo test, on the heels of the announcing of its phase 2 completion of the Rapid Ebola Test 2
... Awarepoint Corporation announced today that CEO Jay Deady will ... Healthcare Innovation Summit on April 14, 10:30 a.m. – ... York. Joining Deady on the panel will be Harry Greenspun, ... Safavi, M.D., vice president and global lead of the Cisco ...
... Encision Inc. (Pink Sheets: ECIA ) ... intensive topics of discussion in recent publications, most notably ...  The potential complications from laparoscopic surgery are highlighted in ... recent California case.  The issue focuses on safer abdominal ...
Cached Medicine Technology:Awarepoint CEO Jay Deady to Serve as Panelist at IBF's Digital Healthcare Innovation Summit 2Awarepoint CEO Jay Deady to Serve as Panelist at IBF's Digital Healthcare Innovation Summit 3Stray Energy Burns Become a "Hot Topic" in Recent Publications 2Stray Energy Burns Become a "Hot Topic" in Recent Publications 3
... optimize the accuracy and precision of Finnpipettes. ... widely recognized by customers throughout the world. ... the years and now covers a full ... filter tips, certified pure tips, stepper tips ...
... Finntips have been designed to optimize the ... of our tip products is widely recognized ... range has been extended over the years ... standard and special tips including filter tips, ...
... Eppendorf Style Low Binding, Graduated Pipet Tips ... fit Eppendorf Style Pipettors.Reduces DNA and protein ... packaged completely by automation. RNAse & DNAse ... 96 tips/rack and 10 racks/cs. AVR100 is ...
... Packed conveniently in plastic-wrapped racks of 96 ... useno need to autoclave. Sterilized Diamond Tips ... sterilization and are delivered with a certificate ... Sterilized Diamond Tips are certified free of ...
Medicine Products: