Navigation Links
New Market Research Study Shows Lung Cancer Treatments Differ Significantly by Both Age and Geography

New Merck KGaA Study Reveals Wide Variations in Therapy Regimens, with Monotherapy Most Common in Elderly Patients and Triplets Most Prevalent in the US

ORLANDO, Fla., June 1 /PRNewswire/ -- There are striking differences in treatment regimens for non-small cell lung cancer (NSCLC) patients, based on both age and geography, according to a new market research study conducted by Merck KGaA, Darmstadt, Germany, presented as a poster on Saturday at the 2009 ASCO (American Society of Clinical Oncology) meeting in Orlando, Florida (Abstract no.: 8053; Poster no.: N15). Performed in conjunction with TNS Healthcare, the representative study shows that among patients with advanced NSCLC, monotherapy is used most often among those 70 or older, while combination therapies are administered most frequently to younger patients. Location also is a key factor in determining therapy choice, with a chemotherapy doublet plus a targeted agent far more common in the US than in Europe.

"While chemotherapy doublets remain the standard regimen for first-line treatment of stage IIIB and IV NSCLC, there are substantial differences among regions in the doublets most often chosen and whether a targeted agent is concurrently administered," says J.F. Vansteenkiste, first author of the poster. "For example, the preferred doublet in Europe is platinum plus gemcitabine, used in 29% of patients. In contrast, in the US and Japan, platinum plus taxanes is predominant, used in more than a quarter of American and more than half of Japanese patients."

"The most extensive use of doublets plus targeted agent is in the US, in contrast with Europe and Japan. Almost half of non-squamous cancer patients younger than 70 are being treated with these combinations in the US. Even among those older than 70, more than a quarter of patients are on chemotherapy doublets plus targeted agent." Randomized phase III studies have shown that adding targeted agents to standard first-line treatments can prolong overall survival.

Almost 5,000 NSCLC Patients Monitored

Merck KGaA already had presented at last year's ASCO a landmark study for Erbitux in combination with standard 1st-line chemotherapy in advanced NSCLC which showed for the first time in 10 years a significant survival benefit in a broad patient population. In the current study Merck KGaA monitored 4,950 patients from May to mid-July 2008 across Western Europe (Spain, Italy, Germany, France and the UK), the US and Japan. TNS Healthcare recruited oncologists in the US, oncologists, radiotherapists and pulmonologists in Europe and pulmonologists and respiratory surgeons in Japan to participate. Physicians who contributed provided information through on-line patient record forms.

About Merck...

Merck is a global pharmaceutical and chemical company with total revenues of euro 7.6 billion in 2008, a history that began in 1668, and a future shaped by 32,700 employees in 60 countries. Its success is characterized by innovations from entrepreneurial employees. Merck's operating activities come under the umbrella of Merck KGaA, in which the Merck family holds an approximately 70% interest and free shareholders own the remaining approximately 30%. In 1917 the U.S. subsidiary Merck & Co. was expropriated and has been an independent company ever since.

About TNS Healthcare...

TNS Healthcare provides market research consulting to the worldwide pharmaceutical, biotech and medical device industries, as well as health-focused ad agencies, media and analysts. It offers globally consistent solutions and custom advisory services to support product introductions; brand, treatment and sales performance optimization; and physician and DTC promotional assessment.

Informing decisions across the life cycle, TNS Healthcare offers action-ready insights for pre- launch landscaping, market and opportunity assessment, segmentation, positioning, message and campaign creation, pricing, forecasting, attitude and awareness measurement and post-launch tracking. It delivers information across stakeholders--including physicians, patients and consumers--to help companies anticipate and impact customers' behaviors. TNS Healthcare provides both qualitative and quantitative offerings, using traditional and on- line methodologies, combining worldwide reach with local expertise.

For more information, visit

SOURCE TNS Healthcare
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Nuvilex Launches Video Marketing Campaign
2. Exclusive Marketplace for Nursing Professionals Launched by Nurses Service Organization
3. Amgens Denosumab and Eli Lillys Forteo/Forsteo Will Drive Robust Annual Growth in the Osteoporosis Drug Market From 2013 to 2018
4. Practice-Reps Brings Sales and Marketing to the Business of Medical Practice Management
5. SAFC(R) & Cherokee Pharmaceuticals(TM) Pool Expertise and Resources With Strategic Partnership For U.S. Market
6. Clearly Contacts Forms Strategic Marketing Alliance with Stockhouse
7. Avantpage Translations Releases White Paper on Capturing The Fastest Growing Healthcare Market In America
8. The Female Health Company Switches to the NASDAQ Stock Market
9. Although the Health Care Market is Recession-Resistant, It Is Not Recession-Immune, According to Millennium Research Groups Medtech Economic Quarterly Publication
10. Astellas Announces New Vice President of Marketing
11. Increasingly Competitive European Dental Implant Market to Reach Over $2.7 Billion by 2013 Despite Unfavorable Economic Conditions
Post Your Comments:
(Date:11/25/2015)... Indianapolis, IN (PRWEB) , ... November 25, 2015 ... ... clean water accessible for all, Water For Empowerment ™ attracts volunteers together ... on clean water by empowering women as key stakeholders in the process. The ...
(Date:11/25/2015)... ... November 25, 2015 , ... Dr. John Pierce, Medical Director ... about hair loss treatment with the Capillus272™ Pro laser therapy cap. FDA cleared for ... and fuller hair, without the need for surgery, prescription pills, or topical foams. ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... people across the country to celebrate their sobriety and show through pictures what ... “before and after” photos this Thanksgiving with the hashtag #FacesOfGratitude on their Facebook, ...
(Date:11/25/2015)... ... 2015 , ... On November 23rd 2015 Cozy Products, a division ... business. Cozy Products explains what this means for business moving forward. , The Tri ... Products business model: to sell personal heaters that reduce energy consumption, are economical and ...
(Date:11/25/2015)... ... November 25, 2015 , ... In an ongoing Clinical Study conducted by ... Chicago, IL, UV Angel is evaluating the efficacy of its product and its disinfection ... (totaling 30 beds) from May 2014 through October 2015 at a 360-bed, acute-care, academic ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... --> --> Juntendo University ... contrast weighting of MRI for patients with Multiple Sclerosis ... agreement with SyntheticMR in order to use SyMRI in clinical ... to generate multiple contrast images from a single scan and ... making it possible to both fine tune images and recreate ...
(Date:11/26/2015)... DUBLIN , November 26, 2015 /PRNewswire/ ... the addition of the "2016 Future ... Drugs of Abuse Testing Market: Supplier Shares, ... report to their offering. --> ... of the "2016 Future Horizons and ...
(Date:11/26/2015)... Nov. 26, 2015 Research and Markets ( ... "Advanced Wound Care Market by Type (Dressings, Therapy Devices, ... (In-Patient Facility, Out-Patient Facility), and Geography - Global Forecast ... --> --> The purpose ... and forecast of the global advanced wound care market. ...
Breaking Medicine Technology: