Navigation Links
New Market Research Study Shows Lung Cancer Treatments Differ Significantly by Both Age and Geography

New Merck KGaA Study Reveals Wide Variations in Therapy Regimens, with Monotherapy Most Common in Elderly Patients and Triplets Most Prevalent in the US

ORLANDO, Fla., June 1 /PRNewswire/ -- There are striking differences in treatment regimens for non-small cell lung cancer (NSCLC) patients, based on both age and geography, according to a new market research study conducted by Merck KGaA, Darmstadt, Germany, presented as a poster on Saturday at the 2009 ASCO (American Society of Clinical Oncology) meeting in Orlando, Florida (Abstract no.: 8053; Poster no.: N15). Performed in conjunction with TNS Healthcare, the representative study shows that among patients with advanced NSCLC, monotherapy is used most often among those 70 or older, while combination therapies are administered most frequently to younger patients. Location also is a key factor in determining therapy choice, with a chemotherapy doublet plus a targeted agent far more common in the US than in Europe.

"While chemotherapy doublets remain the standard regimen for first-line treatment of stage IIIB and IV NSCLC, there are substantial differences among regions in the doublets most often chosen and whether a targeted agent is concurrently administered," says J.F. Vansteenkiste, first author of the poster. "For example, the preferred doublet in Europe is platinum plus gemcitabine, used in 29% of patients. In contrast, in the US and Japan, platinum plus taxanes is predominant, used in more than a quarter of American and more than half of Japanese patients."

"The most extensive use of doublets plus targeted agent is in the US, in contrast with Europe and Japan. Almost half of non-squamous cancer patients younger than 70 are being treated with these combinations in the US. Even among those older than 70, more than a quarter of patients are on chemotherapy doublets plus targeted agent." Randomized phase III studies have shown that adding targeted agents to standard first-line treatments can prolong overall survival.

Almost 5,000 NSCLC Patients Monitored

Merck KGaA already had presented at last year's ASCO a landmark study for Erbitux in combination with standard 1st-line chemotherapy in advanced NSCLC which showed for the first time in 10 years a significant survival benefit in a broad patient population. In the current study Merck KGaA monitored 4,950 patients from May to mid-July 2008 across Western Europe (Spain, Italy, Germany, France and the UK), the US and Japan. TNS Healthcare recruited oncologists in the US, oncologists, radiotherapists and pulmonologists in Europe and pulmonologists and respiratory surgeons in Japan to participate. Physicians who contributed provided information through on-line patient record forms.

About Merck...

Merck is a global pharmaceutical and chemical company with total revenues of euro 7.6 billion in 2008, a history that began in 1668, and a future shaped by 32,700 employees in 60 countries. Its success is characterized by innovations from entrepreneurial employees. Merck's operating activities come under the umbrella of Merck KGaA, in which the Merck family holds an approximately 70% interest and free shareholders own the remaining approximately 30%. In 1917 the U.S. subsidiary Merck & Co. was expropriated and has been an independent company ever since.

About TNS Healthcare...

TNS Healthcare provides market research consulting to the worldwide pharmaceutical, biotech and medical device industries, as well as health-focused ad agencies, media and analysts. It offers globally consistent solutions and custom advisory services to support product introductions; brand, treatment and sales performance optimization; and physician and DTC promotional assessment.

Informing decisions across the life cycle, TNS Healthcare offers action-ready insights for pre- launch landscaping, market and opportunity assessment, segmentation, positioning, message and campaign creation, pricing, forecasting, attitude and awareness measurement and post-launch tracking. It delivers information across stakeholders--including physicians, patients and consumers--to help companies anticipate and impact customers' behaviors. TNS Healthcare provides both qualitative and quantitative offerings, using traditional and on- line methodologies, combining worldwide reach with local expertise.

For more information, visit

SOURCE TNS Healthcare
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Nuvilex Launches Video Marketing Campaign
2. Exclusive Marketplace for Nursing Professionals Launched by Nurses Service Organization
3. Amgens Denosumab and Eli Lillys Forteo/Forsteo Will Drive Robust Annual Growth in the Osteoporosis Drug Market From 2013 to 2018
4. Practice-Reps Brings Sales and Marketing to the Business of Medical Practice Management
5. SAFC(R) & Cherokee Pharmaceuticals(TM) Pool Expertise and Resources With Strategic Partnership For U.S. Market
6. Clearly Contacts Forms Strategic Marketing Alliance with Stockhouse
7. Avantpage Translations Releases White Paper on Capturing The Fastest Growing Healthcare Market In America
8. The Female Health Company Switches to the NASDAQ Stock Market
9. Although the Health Care Market is Recession-Resistant, It Is Not Recession-Immune, According to Millennium Research Groups Medtech Economic Quarterly Publication
10. Astellas Announces New Vice President of Marketing
11. Increasingly Competitive European Dental Implant Market to Reach Over $2.7 Billion by 2013 Despite Unfavorable Economic Conditions
Post Your Comments:
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder ... of ElderCounsel, a national organization of elder law and special needs planning attorneys. “Membership ... rules. It also provides a forum to network with elder law attorneys nationwide,” said ...
(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids this ... by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited about ... ages; it is a non-competitive, non-timed event, which is all about having fun and ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian history ... The Brink” is the creation of published author, William Nowers. Captain Nowers and ... WWII veteran, he spent thirty years in the Navy. Following his career as ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( ), one ... an innovative new design of the shoulder pad. The shoulder pad provides optimal ... controlling your pain while using cold therapy. By utilizing ice and water that is ...
(Date:10/12/2017)... PA (PRWEB) , ... October 12, 2017 , ... ... is the recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B ... York City on October 11, 2017. , The annual award competition recognizes editorial and ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... , Oct. 10, 2017  NDS received FDA 510(k) clearance ... a medical-grade battery-powered display stand specifically designed for endoscopy environments. An ... technology into a clinical solution to support the improvement of patient ... Innovative Design ... Wireless Solution ...
(Date:10/4/2017)... Centers for Disease Control and Prevention (CDC), influenza vaccination should take ... communities across Massachusetts , Connecticut , ... through the end of the month. *Some exclusions apply ... ... by the end of October, according to the Centers for Disease Control ...
(Date:10/2/2017)... , Oct. 2, 2017 Halo Labs announces the European ... system called the HORIZON at MIBio 2017 in Cambridge, ... and visible particulate matter in biopharmaceutical samples with unprecedented speed and ... the novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
Breaking Medicine Technology: