Navigation Links
New MS drug proves effective where others have failed
Date:10/31/2012

e nerve fibre, resulting in physical and cognitive disabilities. The results of a second phase III clinical trial (CARE MS I) also examined the effectiveness of alemtuzumab against the drug interferon beta-1a but in 581 drug-nave patients.

It found that alemtuzumab reduced the number of attacks experienced by people with relapsing-remitting MS by 55 per cent over and above that achieved by interferon beta-1a. Over a two year period, 78 per cent of patients on alemtuzumab compared to 59 per cent of patients on interferon remained relapse free. The proportion of patients experiencing worsening of disability on this trial was slightly lower after alemtuzumab than interferon beta-1a, but this result was not statistically significant.

For both studies, the principal side-effect of treatment with alemtuzumab was the development of other autoimmune diseases. During the trials, roughly 20 per cent of patients developed thyroid autoimmunity and 1 per cent developed an immune thrombocytopenia. Previous work has shown that up to 30 per cent of patients may develop autoimmune thyroid disease over time.

Laboratory work of the Cambridge research team, led by Dr Coles, is investigating how to detect people who are susceptible to these side-effects (funded by the Freemasons' Grand Charity and the Multiple Sclerosis Society in the UK). Additionally, they are currently recruiting for a trial of alemtuzumab in combination with a novel drug to reduce the risk of autoimmune diseases developing as a side-effect of taking alemtuzumab, funded by the Moulton Charitable Foundation and the Medical Research Council (MRC). Both Professor Alastair Compston and Dr Alasdair Coles are supported by the NIHR Biomedical Research Centre, Cambridge.

"Although alemtuzumab causes potentially serious side-effects, these can be identified and treated provided a monitoring schedule is carefully followed. Additionally, we think that we can identify which patients are at risk of auto
'/>"/>

Contact: Genevieve Maul
Genevieve.maul@admin.cam.ac.uk
44-012-237-65542
University of Cambridge
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Clinical insight improves treatment with new lung cancer drug
2. Normalizing tumor blood vessels improves delivery of only the smallest nanomedicines
3. Chemotherapy proves life-saving for some leukemia patients who fail induction therapy
4. Exercise improves quality of life during breast cancer treatment
5. Early treatment improves outcomes in rare, often undiagnosed form of encephalitis
6. NYUCNs Dr. Laura Wagner: Study finds accreditation improves safety culture at nursing homes
7. Cone beam CT proves better for visualizing some causes of hearing loss at half the radiation dose
8. Brief training program improves resident physicians empathy with patients
9. FDA Approves Generic Versions of Plavix
10. A nurse practitioner-driven palliative care intervention improves cancer patients quality of life
11. Oxytocin improves brain function in children with autism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2015)... (PRWEB) , ... August 29, 2015 , ... Brands like ... with zero standard shipping costs. , “Before, a threshold of $49.00 was required ... select brands and items qualify for free standard shipping for customers regardless of the ...
(Date:8/29/2015)... , ... August 29, 2015 , ... The popular television ... Earl Jones, recently announced that it will be devoting an entire short segment to ... millions of people around the globe on a daily basis, but recent advancements in ...
(Date:8/28/2015)... Columbus, Ohio (PRWEB) , ... August 28, 2015 ... ... Saturday’s Imagine No Malaria Day at the Zoo to celebrate children helping children, ... people and their congregations throughout West Ohio have contributed to the United Methodist ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... Understanding the FDA’s Position and Best Practices for Compliance, **Presented by FDAnews ... This workshop, chaired by internationally renowned expert Fubin Wu, has been specifically ...
(Date:8/28/2015)... ... 28, 2015 , ... Saint Petersburg, FL —Pocket Protein™, a ... carbs, sugar, gluten, lactose or caffeine in a convenient 2 oz. pouch that ... Editor’s Choice Awards. , Five consumer packaged goods (CPG) products were selected by ...
Breaking Medicine News(10 mins):Health News:TheBeautyPlace.com Discounts Shipping on Select Brands 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 3Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 2Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 3Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 4Health News:FDAnews Announces — Software and Cybersecurity Risk Management for Medical Devices: Understanding the FDA’s Position and Best Practices for Compliance, Oct. 14-15 5Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 2Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 3
... panic among poultry farmers in Uttar Pradesh after reports got ... Aligarh Farm. Official confirmation is still awaited. ,UP ... are being given antibiotics and vitamins. Samples from the dead ... a lab in Izzatnagar and the Veterinary University, Mathura, although ...
... manufactured TGN-1412, has now admitted that the drug had ... of the six who were admitted to the intensive ... drug administration are recovering, according to official reports. ... Northwick Park Hospital in Harrow, London. Two of the ...
... Australian government has recently started, ads campaigning the need for ... a couch potato all day long//, but the mothers of ... are so. In a medical survey conducted by the government ... or chubby the mothers failed to accept it saying that ...
... of nine more cases of the deadly H5N1 strain of ... by the country's veterinary authorities, two days after nine tufted ... that the ducks were found in the South of the ... Aeroe. ,Authorities in Denmark also confirmed that following ...
... is 24-years-old is one among the first British patients to ... a special device is placed to help her overcome stammering. ... Lieckfeldt said the device would be fitted in her inner ... research that stammerers are helped by speaking in unison with ...
... the cards that will be a landmark on the EM ... project which will come up// in two phases that will ... cancer patients. Bangalore and Ahmedabad will follow suit with ... Foundation chairman, had a meeting with the chief minister to ...
Cached Medicine News:Health News:Drug Company Admits Knowledge Of Side Effects In Monkeys 2
(Date:8/28/2015)... , Aug. 28, 2015 ... has announced the addition of the "Investigation ... to their offering. Developed by AstraZeneca ... is an important drug for the treatment of ... 2000, quetiapine was listed in the Catalogue of ...
(Date:8/28/2015)... DUBLIN , Aug. 28, 2015 ... ) has announced the addition of the ... report to their offering. Developed by ... selective prostaglandin receptor agonist which effectively reduces intraocular ... by FDA, latanoprost (under the trade name of ...
(Date:8/28/2015)... KONG , August 28, 2015 ... in collaboration with one of the leading academics in ... (current world record holder in life extension for model ... insights into biology of aging and age-related diseases, primarily, around ... The work has just been published as "Stability analysis of ...
Breaking Medicine Technology:China Quetiapine Market Investigation Report 2010-2019 2China Latanoprost Market Investigation Report 2015-2019 2Gero: Physics Meets Biology to Help Defeat Aging 2Gero: Physics Meets Biology to Help Defeat Aging 3
... At the end of 2009, the vaccine industry raised ... business media were occupied by various kinds of news ... successfully landed on the Nasdaq, then Simcere, a pharmaceutical ... announced a 50.8% stake in Ealong Biotech and took ...
... EAST HANOVER, N.J., Oct. 16 Novartis announced today ... safety profile of once-yearly Reclast® (zoledronic acid) injection in ... 1,200 women was presented this weekend at the annual ... Research (ASBMR) in Toronto, ON, Canada. The ...
Cached Medicine Technology:Vaccine Leaders All Over the World Talking About China Vaccine Opportunities at VacChina 2010 -- the No.1 China Focused Vaccine Partnering Forum 2Long-Term Data Show Novartis Once-Yearly Reclast Preserves Bone Mass and Provides Fracture Protection in Postmenopausal Osteoporosis 2Long-Term Data Show Novartis Once-Yearly Reclast Preserves Bone Mass and Provides Fracture Protection in Postmenopausal Osteoporosis 3Long-Term Data Show Novartis Once-Yearly Reclast Preserves Bone Mass and Provides Fracture Protection in Postmenopausal Osteoporosis 4Long-Term Data Show Novartis Once-Yearly Reclast Preserves Bone Mass and Provides Fracture Protection in Postmenopausal Osteoporosis 5Long-Term Data Show Novartis Once-Yearly Reclast Preserves Bone Mass and Provides Fracture Protection in Postmenopausal Osteoporosis 6
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: