Navigation Links
New MS drug proves effective where others have failed
Date:10/31/2012

e nerve fibre, resulting in physical and cognitive disabilities. The results of a second phase III clinical trial (CARE MS I) also examined the effectiveness of alemtuzumab against the drug interferon beta-1a but in 581 drug-nave patients.

It found that alemtuzumab reduced the number of attacks experienced by people with relapsing-remitting MS by 55 per cent over and above that achieved by interferon beta-1a. Over a two year period, 78 per cent of patients on alemtuzumab compared to 59 per cent of patients on interferon remained relapse free. The proportion of patients experiencing worsening of disability on this trial was slightly lower after alemtuzumab than interferon beta-1a, but this result was not statistically significant.

For both studies, the principal side-effect of treatment with alemtuzumab was the development of other autoimmune diseases. During the trials, roughly 20 per cent of patients developed thyroid autoimmunity and 1 per cent developed an immune thrombocytopenia. Previous work has shown that up to 30 per cent of patients may develop autoimmune thyroid disease over time.

Laboratory work of the Cambridge research team, led by Dr Coles, is investigating how to detect people who are susceptible to these side-effects (funded by the Freemasons' Grand Charity and the Multiple Sclerosis Society in the UK). Additionally, they are currently recruiting for a trial of alemtuzumab in combination with a novel drug to reduce the risk of autoimmune diseases developing as a side-effect of taking alemtuzumab, funded by the Moulton Charitable Foundation and the Medical Research Council (MRC). Both Professor Alastair Compston and Dr Alasdair Coles are supported by the NIHR Biomedical Research Centre, Cambridge.

"Although alemtuzumab causes potentially serious side-effects, these can be identified and treated provided a monitoring schedule is carefully followed. Additionally, we think that we can identify which patients are at risk of auto
'/>"/>

Contact: Genevieve Maul
Genevieve.maul@admin.cam.ac.uk
44-012-237-65542
University of Cambridge
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Clinical insight improves treatment with new lung cancer drug
2. Normalizing tumor blood vessels improves delivery of only the smallest nanomedicines
3. Chemotherapy proves life-saving for some leukemia patients who fail induction therapy
4. Exercise improves quality of life during breast cancer treatment
5. Early treatment improves outcomes in rare, often undiagnosed form of encephalitis
6. NYUCNs Dr. Laura Wagner: Study finds accreditation improves safety culture at nursing homes
7. Cone beam CT proves better for visualizing some causes of hearing loss at half the radiation dose
8. Brief training program improves resident physicians empathy with patients
9. FDA Approves Generic Versions of Plavix
10. A nurse practitioner-driven palliative care intervention improves cancer patients quality of life
11. Oxytocin improves brain function in children with autism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/1/2015)... Garden City, NY (PRWEB) June 02, 2015 ... honors Lourinda Willey as a 2015-2016 ... Circle. She is recognized with this prestigious distinction for ... is the nation’s leading networking organization exclusively for professional ... operating Local Chapters. , "I’m pleased to present Lourinda ...
(Date:6/1/2015)... NY (PRWEB) June 02, 2015 ... Kathy Everette-Gaines as a 2015-2016 inductee into its ... recognized with this prestigious distinction for leadership in ... exclusively for professional women, boasting more than 700,000 ... “I’m pleased to welcome Kathy into this exceptional ...
(Date:6/1/2015)... Garden City, NY (PRWEB) June 02, 2015 ... honors Lenita F. Cornett, DSL, LSSBB (C), ... Inductee into its VIP Woman of the Year Circle. ... in the military. NAPW is the nation's leading networking ... members and over 200 operating Local Chapters. , “I'm ...
(Date:6/1/2015)... Carson Energy also announced they have selected AdvantaIRA ... Trust, LLC is the country’s largest self-directed IRA administrator. ... using IRA’s does 2 things:, 1. It gives investors ... there current cash position will not allow for participation. ... and their investors to be able to participate in ...
(Date:6/1/2015)... New York (PRWEB) June 01, 2015 ... http://www.testosteronelawsuithub.com/ ) has amended the Case Management Order ... AndroGel testosterone gel. The Amended Order which was ... Illinois on May 29, 2015, directs the parties to ... by August 10, 2015 that outlines parameters and the ...
Breaking Medicine News(10 mins):Health News:National Association of Professional Women Inducts Lourinda Willey, Owner and Principal of Lourinda R. Willey LLC, Into its VIP Professional Woman of the Year Circle 2Health News:The National Association of Professional Women Inducts Kathy Everette-Gaines, Community Relations Coordinator, Into its VIP Professional Woman of the Year Circle 2Health News:National Association of Professional Women Inducts Lenita F. Cornett, First Sergeant of the US Military, Into its VIP Professional Woman of the Year Circle 2Health News:Carson Energy Brings Oil Wells To IRAs 2Health News:Testosterone Lawsuit News: Federal Court Amends Order Governing AndroGel Bellwether Trial Selection 2Health News:Testosterone Lawsuit News: Federal Court Amends Order Governing AndroGel Bellwether Trial Selection 3Health News:Testosterone Lawsuit News: Federal Court Amends Order Governing AndroGel Bellwether Trial Selection 4
... Patricia Raymond offers tips on controlling your flatulence , ... ... is normal and necessary. In fact, the average person passes gas ... three liters daily). However, every body behaves differently and some experience ...
... program provides clients unparalleled live support services for http://www.appointment-plus.com ... ... Scottsdale, AZ (PRWEB) October 8, 2008 -- Appointment-Plus, the ... software client base by bucking trends. In a time ...
... today the extension of its existing strategic alliance with Nano-Terra, Inc., ... ... Germany (Business Wire EON) October 7, 2008 -- The original ... innovative, nanotechnology-based products and solutions based on Merck,s materials. , , ...
... IPRO, one of the,nation,s leading quality ... Liability Company (LLC) that will assume all ... with managed care,organizations (MCOs). The new entity, ... in New York State., (Logo: ...
... CHADD, the nation,s,largest organization serving people ... Annual,International Conference on AD/HD November 12-15 ... some of the leading experts speaking ... adults, clinicians, professionals, and,educators. To view ...
... Getting out of bed sooner helped quality of life after ... The best medicine for intensive care unit (ICU) patients may ... as they,re able, a new report says. , Based ... School of Medicine researchers concluded that the routine use of ...
Cached Medicine News:Health News:Managing Gas Isn't Rocket Science 2Health News:Managing Gas Isn't Rocket Science 3Health News:Appointment-Plus Continues Innovation With Technical Support Program 2Health News: Merck KGaA and Nano-Terra Announce Extension of Nanotechnology Solutions Alliance 2Health News: Merck KGaA and Nano-Terra Announce Extension of Nanotechnology Solutions Alliance 3Health News:IPRO Spins Off Managed Care Review Affiliate 2Health News:Early Mobility Best for ICU Patients 2
(Date:6/1/2015)... June 1, 2015 Researchers from University Hospitals ... Reserve University School of Medicine will present data from ... novel combination treatment for cancer patients with advanced solid ... small cell lung cancer (SCLC), at the 51 st ... in Chicago . ...
(Date:6/1/2015)... LAVAL, QC , June 1, 2015 /CNW Telbec/ -  ... Laval and known under the « Équilibre, ... third quarter Ended on March 31, 2015. All dollar amounts ... Revenues for the third quarter of fiscal year 2015 ... % compared to revenues of $ 3,823,151 for the quarter ...
(Date:6/1/2015)... Women who took vitamin D and calcium supplements ... did not take the supplements, according to a study published ... of the European Menopause and Andropause Society. ... of the Women,s Health Initiative , one of the ... causes of death, disability and impaired quality of life in ...
Breaking Medicine Technology:UH Case Medical Center Experts to Present Data at 51st ASCO Annual Meeting 2UH Case Medical Center Experts to Present Data at 51st ASCO Annual Meeting 3Third Quarter results - Fiscal 2015 - Ergoresearch reports its results for the quarter ended March 31, 2015 2Third Quarter results - Fiscal 2015 - Ergoresearch reports its results for the quarter ended March 31, 2015 3Third Quarter results - Fiscal 2015 - Ergoresearch reports its results for the quarter ended March 31, 2015 4Vitamin D and Calcium Supplements Do Not Improve Menopausal Symptoms 2Vitamin D and Calcium Supplements Do Not Improve Menopausal Symptoms 3Vitamin D and Calcium Supplements Do Not Improve Menopausal Symptoms 4
... 17, 2010 The Medical Device practice at,MarketsandMarkets is pleased to announce ... India , China (BRIC) 2010 - 2015. , ... Browse in-depth TOC on Diagnostic ... (BRIC) 2010 - 2015 Market Report. Early buyers will receive 10%,customization of ...
... June 16 Tomorrow, the Food and Drug Administration (FDA) will hold a hearing ... an emergency contraceptive, or a new "Plan B." , ... http://photos.prnewswire.com/prnh/20080930/FRCLOGO ) , , , ... , , ...
Cached Medicine Technology:Diagnostic Imaging Markets in Brazil, Russia, India, China (BRIC) 2010 - 2015: MarketsandMarkets 2Diagnostic Imaging Markets in Brazil, Russia, India, China (BRIC) 2010 - 2015: MarketsandMarkets 3Diagnostic Imaging Markets in Brazil, Russia, India, China (BRIC) 2010 - 2015: MarketsandMarkets 4FRC Urges FDA to Reject New Abortion Drug Falsely Labeled as an Emergency Contraceptive 2
The proximally modular S-ROM Total Hip System provides custom capability at non-custom prices and is competitive with conventional porous coated systems....
Quatroloc Revision Hip System...
Severe revision options for the knee and hip...
Severe revision options for the knee and hip...
Medicine Products: